Gene-panel testing of breast and ovarian cancer patients identifies a recurrent RAD51C duplication

Time to incorporate germline multigene panel testing into breast and ovarian cancer patient care

(2016) Rossella Graffeo et al.   BREAST CANCER RESEARCH AND TREATMENT

Male breast cancer in a multi-gene panel testing cohort: insights and unexpected results

(2016) Mary Pritzlaff et al.   BREAST CANCER RESEARCH AND TREATMENT

Age- and Tumor Subtype–Specific Breast Cancer Risk Estimates for CHEK2*1100delC Carriers

(2016) Marjanka K. Schmidt et al.   JOURNAL OF CLINICAL ONCOLOGY

Patterns of genic intolerance of rare copy number variation in 59,898 human exomes

(2016) Douglas M Ruderfer et al.   NATURE GENETICS

Breast cancer risk and clinical implications for germline PTEN mutation carriers

(2015) Joanne Ngeow et al.   BREAST CANCER RESEARCH AND TREATMENT

CHEK2mutations and the risk of papillary thyroid cancer

(2015) Monika Siołek et al.   INTERNATIONAL JOURNAL OF CANCER

Contribution of Germline Mutations in the RAD51B, RAD51C, and RAD51D Genes to Ovarian Cancer in the Population

(2015) Honglin Song et al.   JOURNAL OF CLINICAL ONCOLOGY

A Systematic Comparison of Traditional and Multigene Panel Testing for Hereditary Breast and Ovarian Cancer Genes in More Than 1000 Patients

(2015) Stephen E. Lincoln et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer

(2015) Susan J. Ramus et al.   JNCI-Journal of the National Cancer Institute

Identification of six new susceptibility loci for invasive epithelial ovarian cancer

(2015) Karoline B Kuchenbaecker et al.   NATURE GENETICS

Genome-wide association analysis of more than 120,000 individuals identifies 15 new susceptibility loci for breast cancer

(2015) Kyriaki Michailidou et al.   NATURE GENETICS

Gene-Panel Sequencing and the Prediction of Breast-Cancer Risk

(2015) Douglas F. Easton et al.   NEW ENGLAND JOURNAL OF MEDICINE

Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer

(2015) Susan J. Ramus et al.   JNCI-Journal of the National Cancer Institute

Hereditary Diffuse Gastric Cancer Syndrome

(2015) Samantha Hansford et al.   JAMA Oncology

Frequency of mutations in individuals with breast cancer referred forBRCA1andBRCA2testing using next-generation sequencing with a 25-gene panel

(2014) Nadine Tung et al.   CANCER

Li-Fraumeni syndrome: cancer risk assessment and clinical management

(2014) Kate A. McBride et al.   Nature Reviews Clinical Oncology

Breast-Cancer Risk in Families with Mutations in PALB2

(2014) Antonis C. Antoniou et al.   NEW ENGLAND JOURNAL OF MEDICINE

Genetic Susceptibility to Triple-Negative Breast Cancer

(2013) K. N. Stevens et al.   CANCER RESEARCH

Cancer Risks for BRCA1 and BRCA2 Mutation Carriers: Results From Prospective Analysis of EMBRACE

(2013) Nasim Mavaddat et al.   JNCI-Journal of the National Cancer Institute

Breast cancer-associated missense mutants of the PALB2 WD40 domain, which directly binds RAD51C, RAD51 and BRCA2, disrupt DNA repair

(2013) J-Y Park et al.   ONCOGENE

A Finnish founder mutation inRAD51D: analysis in breast, ovarian, prostate, and colorectal cancer: Table 1

(2012) Liisa M Pelttari et al.   JOURNAL OF MEDICAL GENETICS

Germline RAD51C mutations confer susceptibility to ovarian cancer

(2012) Chey Loveday et al.   NATURE GENETICS

RAD51C is a susceptibility gene for ovarian cancer

(2011) Liisa M. Pelttari et al.   HUMAN MOLECULAR GENETICS

Describing structural changes by extending HGVS sequence variation nomenclature

(2011) Peter E.M. Taschner et al.   HUMAN MUTATION

Dominant-Negative Features of Mutant TP53 in Germline Carriers Have Limited Impact on Cancer Outcomes

(2011) P. Monti et al.   MOLECULAR CANCER RESEARCH

Germline mutations in RAD51D confer susceptibility to ovarian cancer

(2011) Chey Loveday et al.   NATURE GENETICS

Mutations in 12 genes for inherited ovarian, fallopian tube, and peritoneal carcinoma identified by massively parallel sequencing

(2011) T. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

RAD51 paralogs: Roles in DNA damage signalling, recombinational repair and tumorigenesis

(2011) Natsuko Suwaki et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

High Cancer Risk in Peutz–Jeghers Syndrome: A Systematic Review and Surveillance Recommendations

(2010) M G F van Lier et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

The Genome-wide Patterns of Variation Expose Significant Substructure in a Founder Population

(2008) Eveliina Jakkula et al.   AMERICAN JOURNAL OF HUMAN GENETICS

CHEK2 1100delC and male breast cancer in the Netherlands

(2008) Marijke Wasielewski et al.   BREAST CANCER RESEARCH AND TREATMENT