Recent Advances in Transition Metal-Catalyzed Asymmetric Radical Reactions

Asymmetric Radical Bicyclization of Allyl Azidoformates via Cobalt(II)-Based Metalloradical Catalysis

(2017) Huiling Jiang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Cu-Catalyzed Intermolecular Trifluoromethylarylation of Styrenes: Enantioselective Arylation of Benzylic Radicals

(2017) Lianqian Wu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Copper-Catalyzed Intermolecular Aminoarylation of Styrenes: Efficient Access to Optical 2,2-Diarylethylamines

(2017) Dinghai Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Asymmetric Reductive Cross-Coupling To Access 1,1-Diarylalkanes

(2017) Kelsey E. Poremba et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Radical Cyclopropanation of Alkenes with In Situ-Generated Donor-Substituted Diazo Reagents via Co(II)-Based Metalloradical Catalysis

(2017) Yong Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Enantioselective Reductive Cross-Coupling of Styrenyl Aziridines

(2017) Brian P. Woods et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Enantioselective Cross-Coupling of N-Hydroxyphthalimide Esters with Vinyl Bromides

(2017) Naoyuki Suzuki et al.   ORGANIC LETTERS

Metalloradical activation of α-formyldiazoacetates for the catalytic asymmetric radical cyclopropanation of alkenes

(2017) Xue Xu et al.   Chemical Science

Catalytic asymmetric radical aminoperfluoroalkylation and aminodifluoromethylation of alkenes to versatile enantioenriched-fluoroalkyl amines

(2017) Jin-Shun Lin et al.   Nature Communications

Total Synthesis of (−)-Daphenylline

(2016) Ryosuke Yamada et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cascade polycyclizations in natural product synthesis

(2016) R. Ardkhean et al.   CHEMICAL SOCIETY REVIEWS

A Rhodium Catalyst Superior to Iridium Congeners for Enantioselective Radical Amination Activated by Visible Light

(2016) Xiaodong Shen et al.   CHEMISTRY-A EUROPEAN JOURNAL

Synthesis of Neurotrophic Seco-prezizaane Sesquiterpenes (1R,10S)-2-Oxo-3,4-dehydroneomajucin, (2S)-Hydroxy-3,4-dehydroneomajucin, and (−)-Jiadifenin

(2016) Xiayun Cheng et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Dual-Catalytic Strategy To Direct Asymmetric Radical Aminotrifluoromethylation of Alkenes

(2016) Jin-Shun Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Copper-Catalyzed Intermolecular Cyanotrifluoromethylation of Alkenes via Radical Process

(2016) Fei Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Decarboxylative Arylation of α-Amino Acids via the Merger of Photoredox and Nickel Catalysis

(2016) Zhiwei Zuo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective organocatalysis using SOMO activation

(2016) Mária Mečiarová et al.   NEW JOURNAL OF CHEMISTRY

Enantioselective synthesis of an ophiobolin sesterterpene via a programmed radical cascade

(2016) Z. G. Brill et al.   SCIENCE

A general, modular method for the catalytic asymmetric synthesis of alkylboronate esters

(2016) J. Schmidt et al.   SCIENCE

Asymmetric copper-catalyzed C-N cross-couplings induced by visible light

(2016) Q. M. Kainz et al.   SCIENCE

Enantioselective cyanation of benzylic C–H bonds via copper-catalyzed radical relay

(2016) Wen Zhang et al.   SCIENCE

Sm(II)-Mediated Electron Transfer to Carboxylic Acid Derivatives: Development of Complexity-Generating Cascades

(2015) Xavier Just-Baringo et al.   ACCOUNTS OF CHEMICAL RESEARCH

Methodologies Limiting or Avoiding Contamination by Organotin Residues in Organic Synthesis

(2015) Erwan Le Grognec et al.   CHEMICAL REVIEWS

Carbon-Centered Radical Addition to C=X Bonds for C−X Bond Formation

(2015) Dong Liu et al.   Chemistry-An Asian Journal

Enantioselective Cross-Coupling of meso-Epoxides with Aryl Halides

(2015) Yang Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoconvergent Negishi Arylations of Racemic Secondary Alkyl Electrophiles: Differentiating between a CF3 and an Alkyl Group

(2015) Yufan Liang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective, Catalytic Trichloromethylation through Visible-Light-Activated Photoredox Catalysis with a Chiral Iridium Complex

(2015) Haohua Huo et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Versatile Enantioselective Synthesis of Functionalized Lactones via Copper-Catalyzed Radical Oxyfunctionalization of Alkenes

(2015) Rong Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Asymmetric Reductive Cross-Coupling between Heteroaryl Iodides and α-Chloronitriles

(2015) Nathaniel T. Kadunce et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Stereoselective radical C–H alkylation with acceptor/acceptor-substituted diazo reagents via Co(ii)-based metalloradical catalysis

(2015) Xin Cui et al.   Chemical Science

Catalytic enantioselective organic transformations via visible light photocatalysis

(2015) Chengfeng Wang et al.   Organic Chemistry Frontiers

Endeavors to Access Molecular Complexity: Strategic Use of Free Radicals in Natural Product Synthesis

(2014) Takehiko Yoshimitsu   CHEMICAL RECORD

Single Electron Transfer in Radical Ion and Radical-Mediated Organic, Materials and Polymer Synthesis

(2014) Na Zhang et al.   CHEMICAL REVIEWS

Cross-Coupling Reactions Using Samarium(II) Iodide

(2014) Michal Szostak et al.   CHEMICAL REVIEWS

Stereoconvergent Arylations and Alkenylations of Unactivated Alkyl Electrophiles: Catalytic Enantioselective Synthesis of Secondary Sulfonamides and Sulfones

(2014) Junwon Choi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Asymmetric Reductive Cross-Coupling Between Vinyl and Benzyl Electrophiles

(2014) Alan H. Cherney et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Negishi Arylations of Propargylic Bromides: A Mechanistic Investigation

(2014) Nathan D. Schley et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric photoredox transition-metal catalysis activated by visible light

(2014) Haohua Huo et al.   NATURE

Recent advances in homogeneous nickel catalysis

(2014) Sarah Z. Tasker et al.   NATURE

Effective Synthesis of ChiralN-Fluoroaryl Aziridines through Enantioselective Aziridination of Alkenes with Fluoroaryl Azides

(2013) Li-Mei Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nickel-Catalyzed Decarbonylative CH Coupling Reactions: A Strategy for Preparing Bis(heteroaryl) Backbones

(2013) Arkaitz Correa et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Enantioselective Functionalization of Radical Intermediates in Redox Catalysis: Copper-Catalyzed Asymmetric Oxytrifluoromethylation of Alkenes

(2013) Rong Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cobalt(II)-Catalyzed Asymmetric Olefin Cyclopropanation with α-Ketodiazoacetates

(2013) Xue Xu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Exo-DigRadical Cascades of Skipped Enediynes: Building a Naphthalene Moiety within a Polycyclic Framework

(2013) Kamalkishore Pati et al.   CHEMISTRY-A EUROPEAN JOURNAL

A Structurally Rigid Bis(amido) Ligand Framework in Low-Coordinate Ni(I), Ni(II), and Ni(III) Analogues Provides Access to a Ni(III) Methyl Complex via Oxidative Addition

(2013) Michael I. Lipschutz et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Carbon–Carbon Bond-Forming Reactions of Unactivated Tertiary Alkyl Halides: Suzuki Arylations

(2013) Susan L. Zultanski et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Reductive Acyl Cross-Coupling: Synthesis of Enantioenriched Acyclic α,α-Disubstituted Ketones

(2013) Alan H. Cherney et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Direct α-Amination of Aldehydes via a Photoredox Mechanism: A Strategy for Asymmetric Amine Fragment Coupling

(2013) Giuseppe Cecere et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel/Bis(oxazoline)-Catalyzed Asymmetric Negishi Arylations of Racemic Secondary Benzylic Electrophiles to Generate Enantioenriched 1,1-Diarylalkanes

(2013) Hien-Quang Do et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Titanium(III)-Catalyzed Reductive Cyclization of Ketonitriles

(2012) Jan Streuff et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Intramolecular Alkoxycyanation and Alkoxyacylation Reactions: New Types of Alkene Difunctionalizations for the Construction of Oxygen Heterocycles

(2012) John P. Wolfe   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Progress in Nickel-Catalyzed Biaryl Coupling

(2012) Junichiro Yamaguchi et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Catalytic Enantioselective Cross-Couplings of Secondary Alkyl Electrophiles with Secondary Alkylmetal Nucleophiles: Negishi Reactions of Racemic Benzylic Bromides with Achiral Alkylzinc Reagents

(2012) Jörg T. Binder et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Enantioselective Cross-Couplings of Racemic Secondary Electrophiles That Bear an Oxygen Leaving Group

(2012) Alexander J. Oelke et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Synthesis of Secondary Nitriles via Stereoconvergent Negishi Arylations and Alkenylations of Racemic α-Bromonitriles

(2012) Junwon Choi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Total Synthesis of (±)-Bisabosqual A

(2012) Christopher W. am Ende et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Coupling Reactions of Alkyl Electrophiles, Including Unactivated Tertiary Halides, To Generate Carbon–Boron Bonds

(2012) Alexander S. Dudnik et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Ni- and Fe-Catalyzed Cross-Coupling Reactions of Phenol Derivatives

(2012) Tehetena Mesganaw et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Total Synthesis of Carolacton, a Highly Potent Biofilm Inhibitor

(2011) Thomas Schmidt et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium(II)-Catalyzed Alkene Functionalization via Nucleopalladation: Stereochemical Pathways and Enantioselective Catalytic Applications

(2011) Richard I. McDonald et al.   CHEMICAL REVIEWS

Activation of “Inert” Alkenyl/Aryl CO Bond and Its Application in Cross-Coupling Reactions

(2011) Bi-Jie Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

Enantioselective Cyclopropenation of Alkynes with Acceptor/Acceptor-Substituted Diazo Reagents via Co(II)-Based Metalloradical Catalysis

(2011) Xin Cui et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Short Total Synthesis of (±)-Epimeloscine and (±)-Meloscine Enabled by a Cascade Radical Annulation of a Divinylcyclopropane

(2011) Hanmo Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Experimental Evidence for Cobalt(III)-Carbene Radicals: Key Intermediates in Cobalt(II)-Based Metalloradical Cyclopropanation

(2011) Hongjian Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly Asymmetric Intramolecular Cyclopropanation of Acceptor-Substituted Diazoacetates by Co(II)-Based Metalloradical Catalysis: Iterative Approach for Development of New-Generation Catalysts

(2011) Xue Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Exploration of New C−O Electrophiles in Cross-Coupling Reactions

(2010) Da-Gang Yu et al.   ACCOUNTS OF CHEMICAL RESEARCH

Nickel-Catalyzed Cross-Couplings Involving Carbon−Oxygen Bonds

(2010) Brad M. Rosen et al.   CHEMICAL REVIEWS

SmI2-induced reductive cyclizations for the synthesis of cyclic ethers and applications in natural product synthesis

(2010) Tadashi Nakata   CHEMICAL SOCIETY REVIEWS

Enantioselective Alkenylation via Nickel-Catalyzed Cross-Coupling with Organozirconium Reagents

(2010) Sha Lou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel/Bis(oxazoline)-Catalyzed Asymmetric Kumada Reactions of Alkyl Electrophiles: Cross-Couplings of Racemic α-Bromoketones

(2010) Sha Lou et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Asymmetric Suzuki Cross-Couplings of Activated Secondary Alkyl Electrophiles: Arylations of Racemic α-Chloroamides

(2010) Pamela M. Lundin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A General and Efficient Cobalt(II)-Based Catalytic System for Highly Stereoselective Cyclopropanation of Alkenes with α-Cyanodiazoacetates

(2010) Shifa Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Enantioselective Radical Cyclization via Regiodivergent Epoxide Opening

(2010) Andreas Gansäuer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Light-Driven Enantioselective Organocatalysis

(2009) Christiane Müller et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Highly asymmetric cobalt-catalyzed aziridination of alkenes with trichloroethoxysulfonyl azide (TcesN3)

(2009) Velusamy Subbarayan et al.   CHEMICAL COMMUNICATIONS

Enantioselective α-Trifluoromethylation of Aldehydes via Photoredox Organocatalysis

(2009) David A. Nagib et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mechanisms of Mn(OAc)3-based oxidative free-radical additions and cyclizations

(2009) Barry B. Snider   TETRAHEDRON

Catalytic Asymmetric Cross-Couplings of Racemic α-Bromoketones with Arylzinc Reagents

(2008) Pamela M. Lundin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Acceptor/Acceptor-Substituted Diazo Reagents for Carbene Transfers: Cobalt-Catalyzed AsymmetricZ-Cyclopropanation of Alkenes with α-Nitrodiazoacetates

(2008) Shifa Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cobalt-Catalyzed Asymmetric Cyclopropanation with Diazosulfones: Rigidification and Polarization of Ligand Chiral Environment via Hydrogen Bonding and Cyclization

(2008) Shifa Zhu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Catalytic Asymmetric Hiyama Cross-Couplings of Racemic α-Bromo Esters

(2008) Xing Dai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Asymmetric Negishi Cross-Couplings of Secondary Allylic Chlorides with Alkylzincs

(2008) Sunghee Son et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nickel-Catalyzed Asymmetric Cross-Couplings of Racemic Propargylic Halides with Arylzinc Reagents

(2008) Sean W. Smith et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Sustainable Radical Reduction through Catalytic Hydrogen Atom Transfer

(2008) Andreas Gansäuer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Short Synthesis of (−)-Cephalotaxine Using a Radical Cascade

(2008) Tsuyoshi Taniguchi et al.   ORGANIC LETTERS

Merging Photoredox Catalysis with Organocatalysis: The Direct Asymmetric Alkylation of Aldehydes

(2008) D. A. Nicewicz et al.   SCIENCE