The Anticancer Potential of Peroxisome Proliferator-Activated Receptor Antagonists
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Title
The Anticancer Potential of Peroxisome Proliferator-Activated Receptor Antagonists
Authors
Keywords
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Journal
ChemMedChem
Volume 13, Issue 3, Pages 209-219
Publisher
Wiley
Online
2017-12-25
DOI
10.1002/cmdc.201700703
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- (2015) Ulises D. Orlando et al. Oncotarget
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- (2014) P.-L. Yao et al. MOLECULAR CANCER THERAPEUTICS
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- (2014) Bogna Grygiel-Górniak Nutrition Journal
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- (2014) Martina I. Lefterova et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
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- Inhibition of PPARα Induces Cell Cycle Arrest and Apoptosis, and Synergizes with Glycolysis Inhibition in Kidney Cancer Cells
- (2013) Omran Abu Aboud et al. PLoS One
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- (2012) A. Neumann et al. DIABETOLOGIA
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- (2012) D E Spaner et al. LEUKEMIA
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- (2008) Yekaterina Y Zaytseva et al. Molecular Cancer
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