A Step into the Future: Applications of Nanoparticle Enzyme Mimics

Glycine-functionalized copper(ii) hydroxide nanoparticles with high intrinsic superoxide dismutase activity

(2017) Karsten Korschelt et al.   Nanoscale

Mitochondria-Targeting Ceria Nanoparticles as Antioxidants for Alzheimer’s Disease

(2016) Hyek Jin Kwon et al.   ACS Nano

Haloperoxidase Mimicry by CeO2−xNanorods Combats Biofouling

(2016) Karoline Herget et al.   ADVANCED MATERIALS

Genetic Optimization of Metalloenzymes: Enhancing Enzymes for Non-Natural Reactions

(2016) Todd K. Hyster et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Self-Assembly of Multi-nanozymes to Mimic an Intracellular Antioxidant Defense System

(2016) Yanyan Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cover Picture: Asymmetric Catalytic Aza-Diels-Alder/Ring-Closing Cascade Reaction Forming Bicyclic Azaheterocycles by Trienamine Catalysis (Chem. Eur. J. 1/2017)

(2016) Yang Li et al.   CHEMISTRY-A EUROPEAN JOURNAL

The nanotechnology of life-inspired systems

(2016) Bartosz A. Grzybowski et al.   Nature Nanotechnology

Molecular catalysis science: Perspective on unifying the fields of catalysis

(2016) Rong Ye et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimalist Protein Engineering of an Aldolase Provokes Unprecedented Substrate Promiscuity

(2016) Deniz Güclü et al.   ACS Catalysis

Intrinsic superoxide dismutase activity of MnO nanoparticles enhances the magnetic resonance imaging contrast

(2016) R. Ragg et al.   Journal of Materials Chemistry B

Hydrothermal vents and prebiotic chemistry: a review

(2016) María Colín-García   Boletin de la Sociedad Geologica Mexicana

Nanozymes in bionanotechnology: from sensing to therapeutics and beyond

(2016) Xiaoyu Wang et al.   Inorganic Chemistry Frontiers

Redox homeostasis protects mitochondria through accelerating ROS conversion to enhance hypoxia resistance in cancer cells

(2016) Pengying Li et al.   Scientific Reports

Drug-induced reactive oxygen species (ROS) rely on cell membrane properties to exert anticancer effects

(2016) Hamid R. Molavian et al.   Scientific Reports

Expanding the Enzyme Universe: Accessing Non-Natural Reactions by Mechanism-Guided Directed Evolution

(2015) Hans Renata et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Vacancy-Engineered Nanoceria: Enzyme Mimetic Hotspots for the Degradation of Nerve Agents

(2015) Amit A. Vernekar et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

White biotechnology: State of the art strategies for the development of biocatalysts for biorefining

(2015) S. Heux et al.   BIOTECHNOLOGY ADVANCES

A Remarkably Efficient MnFe2O4-based Oxidase Nanozyme

(2015) Amit A. Vernekar et al.   Chemistry-An Asian Journal

Solids Go Bio: Inorganic Nanoparticles as Enzyme Mimics

(2015) Ruben Ragg et al.   EUROPEAN JOURNAL OF INORGANIC CHEMISTRY

Supramolecular regulation of bioorthogonal catalysis in cells using nanoparticle-embedded transition metal catalysts

(2015) Gulen Yesilbag Tonga et al.   Nature Chemistry

Untangling the biological effects of cerium oxide nanoparticles: the role of surface valence states

(2015) Gerardo Pulido-Reyes et al.   Scientific Reports

Mysteries of Metals in Metalloenzymes

(2014) Crystal E. Valdez et al.   ACCOUNTS OF CHEMICAL RESEARCH

Catalytically Active Nanomaterials: A Promising Candidate for Artificial Enzymes

(2014) Youhui Lin et al.   ACCOUNTS OF CHEMICAL RESEARCH

Role of Dynamics in Enzyme Catalysis: Substantial versus Semantic Controversies

(2014) Amnon Kohen   ACCOUNTS OF CHEMICAL RESEARCH

Environmentally Benign Sol–Gel Antifouling and Foul-Releasing Coatings

(2014) Michael R. Detty et al.   ACCOUNTS OF CHEMICAL RESEARCH

Molybdenum Trioxide Nanoparticles with Intrinsic Sulfite Oxidase Activity

(2014) Ruben Ragg et al.   ACS Nano

Cerium oxide nanoparticles attenuate monocrotaline induced right ventricular hypertrophy following pulmonary arterial hypertension

(2014) Madhukar B. Kolli et al.   BIOMATERIALS

The effect of cerium valence states at cerium oxide nanoparticle surfaces on cell proliferation

(2014) Tamaki Naganuma et al.   BIOMATERIALS

Superoxide Dismutases and Superoxide Reductases

(2014) Yuewei Sheng et al.   CHEMICAL REVIEWS

Protein Design: Toward Functional Metalloenzymes

(2014) Fangting Yu et al.   CHEMICAL REVIEWS

Metalloenzyme design and engineering through strategic modifications of native protein scaffolds

(2014) Igor D Petrik et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Beneficial Effects of Cerium Oxide Nanoparticles in Development of Chondrocyte-Seeded Hydrogel Constructs and Cellular Response to Interleukin Insults

(2014) Sathish Ponnurangam et al.   TISSUE ENGINEERING PART A

An antioxidant nanozyme that uncovers the cytoprotective potential of vanadia nanowires

(2014) Amit A. Vernekar et al.   Nature Communications

Oxidative stress and free radicals in COPD – implications and relevance for treatment

(2014) Wolfgang Domej et al.   International Journal of Chronic Obstructive Pulmonary Disease

Computational Enzyme Design

(2013) Gert Kiss et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bromoperoxidase activity of amavadin dissected: a DFT investigation

(2013) Giuseppe Zampella et al.   CHEMICAL COMMUNICATIONS

Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes

(2013) Hui Wei et al.   CHEMICAL SOCIETY REVIEWS

The molybdenum oxotransferases and related enzymes

(2013) Russ Hille   DALTON TRANSACTIONS

The role of vanadium haloperoxidases in the formation of volatile brominated compounds and their impact on the environment

(2013) Ron Wever et al.   DALTON TRANSACTIONS

Nanoceria: A Rare-Earth Nanoparticle as a Novel Anti-Angiogenic Therapeutic Agent in Ovarian Cancer

(2013) Shailendra Giri et al.   PLoS One

Cerium oxide caged metal chelator: anti-aggregation and anti-oxidation integrated H2O2-responsive controlled drug release for potential Alzheimer's disease treatment

(2013) Meng Li et al.   Chemical Science

Anti-bacterial and in vivo tumor treatment by reactive oxygen species generated by magnetic nanoparticles

(2013) Di Zhang et al.   Journal of Materials Chemistry B

Cerium Oxide Nanoparticles Protect Cardiac Progenitor Cells from Oxidative Stress

(2012) Francesca Pagliari et al.   ACS Nano

Ceria Nanoparticles that can Protect against Ischemic Stroke

(2012) Chi Kyung Kim et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Downregulation of Tumor Growth and Invasion by Redox-Active Nanoparticles

(2012) Lirija Alili et al.   ANTIOXIDANTS & REDOX SIGNALING

Effects of cerium oxide nanoparticles on the growth of keratinocytes, fibroblasts and vascular endothelial cells in cutaneous wound healing

(2012) Srinivasulu Chigurupati et al.   BIOMATERIALS

Alzheimer Mechanisms and Therapeutic Strategies

(2012) Yadong Huang et al.   CELL

Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling

(2012) Paul D. Ray et al.   CELLULAR SIGNALLING

Iron phosphate microflowers as peroxidase mimic and superoxide dismutase mimic for biocatalysis and biosensing

(2012) Wei Wang et al.   CHEMICAL COMMUNICATIONS

Mineral–organic interfacial processes: potential roles in the origins of life

(2012) H. James Cleaves II et al.   CHEMICAL SOCIETY REVIEWS

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Vanadium pentoxide nanoparticles mimic vanadium haloperoxidases and thwart biofilm formation

(2012) Filipe Natalio et al.   Nature Nanotechnology

Magnetoferritin nanoparticles for targeting and visualizing tumour tissues

(2012) Kelong Fan et al.   Nature Nanotechnology

Vanadium bromoperoxidase from Delisea pulchra: enzyme-catalyzed formation of bromofuranone and attendant disruption of quorum sensing

(2011) Moriah Sandy et al.   CHEMICAL COMMUNICATIONS

V2O5 nanowires with an intrinsic iodination activity leading to the formation of self-assembled melanin-like biopolymers

(2011) Filipe Natalio et al.   JOURNAL OF MATERIALS CHEMISTRY

The Mitochondria-Targeted Antioxidant MitoQ Prevents Loss of Spatial Memory Retention and Early Neuropathology in a Transgenic Mouse Model of Alzheimer's Disease

(2011) M. J. McManus et al.   JOURNAL OF NEUROSCIENCE

V2O5 Nanowires with an Intrinsic Peroxidase-Like Activity

(2010) Rute André et al.   ADVANCED FUNCTIONAL MATERIALS

Stem Cell Aligned Growth Induced by CeO2 Nanoparticles in PLGA Scaffolds with Improved Bioactivity for Regenerative Medicine

(2010) Corrado Mandoli et al.   ADVANCED FUNCTIONAL MATERIALS

Enzyme Mimics Based Upon Supramolecular Coordination Chemistry

(2010) Michael J. Wiester et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Nanoceria exhibit redox state-dependent catalase mimetic activity

(2010) Talib Pirmohamed et al.   CHEMICAL COMMUNICATIONS

Rare earth oxides as nanoadditives in 3-D nanocomposite scaffolds for bone regeneration

(2010) Ajay S. Karakoti et al.   JOURNAL OF MATERIALS CHEMISTRY

Phosphate ester hydrolysis of biologically relevant molecules by cerium oxide nanoparticles

(2010) Melissa Hirsch Kuchma et al.   Nanomedicine-Nanotechnology Biology and Medicine

Production and role of volatile halogenated compounds from marine algae

(2010) Carsten Paul et al.   NATURAL PRODUCT REPORTS

Alzheimer's Disease

(2010) Henry W. Querfurth et al.   NEW ENGLAND JOURNAL OF MEDICINE

Successful Treatment of Molybdenum Cofactor Deficiency Type A With cPMP

(2010) A. Veldman et al.   PEDIATRICS

Heme-Like Coordination Chemistry Within Nanoporous Molecular Crystals

(2010) C. G. Bezzu et al.   SCIENCE

Oxidase-Like Activity of Polymer-Coated Cerium Oxide Nanoparticles

(2009) Atul Asati et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Alzheimer's Disease: From Pathology to Therapeutic Approaches

(2009) Roland Jakob-Roetne et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Biomimetic Chemistry of Iron, Nickel, Molybdenum, and Tungsten in Sulfur-Ligated Protein Sites†

(2009) Stanislav Groysman et al.   BIOCHEMISTRY

On the origin of life in the Zinc world. 2. Validation of the hypothesis on the photosynthesizing zinc sulfide edifices as cradles of life on Earth

(2009) Armen Y Mulkidjanian et al.   Biology Direct

Oxidative Stress and Its Role in the Pathogenesis of Ischaemic Stroke

(2009) C. L. Allen et al.   International Journal of Stroke

Reducing Stress on Cells with Apoferritin-Encapsulated Platinum Nanoparticles

(2009) Lianbing Zhang et al.   NANO LETTERS

Mechanistic considerations of halogenating enzymes

(2009) Alison Butler et al.   NATURE

Molybdenum cofactors, enzymes and pathways

(2009) Günter Schwarz et al.   NATURE

Nitric Oxide Links Mitochondrial Fission to Alzheimer's Disease

(2009) B. Westermann   Science Signaling

Photoactivated Biotemplated Nanoparticles as an Enzyme Mimic

(2008) Joseph M. Slocik et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Redox compartmentalization in eukaryotic cells

(2008) Young-Mi Go et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Halogenation Strategies In Natural Product Biosynthesis

(2008) Christopher S. Neumann et al.   CHEMISTRY & BIOLOGY

Manganous Phosphate Acts as a Superoxide Dismutase

(2008) Kevin Barnese et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease

(2008) Heng Du et al.   NATURE MEDICINE

Hydrothermal vents and the origin of life

(2008) William Martin et al.   NATURE REVIEWS MICROBIOLOGY