Recent Advances in the Synthesis of Peptoid Macrocycles

Conformational isomerism in cyclic peptoids and its specification

(2017) A. D'Amato et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of biaryl-linked cyclic peptoids

(2017) Alexandra M. Webster et al.   TETRAHEDRON LETTERS

Exploring the links between peptoid antibacterial activity and toxicity

(2017) H. L. Bolt et al.   MedChemComm

Solid-State Conformational Flexibility at Work: Zipping and Unzipping within a Cyclic Peptoid Single Crystal

(2016) Alessandra Meli et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Peptoid Efficacy against Polymicrobial Biofilms Determined by Using Propidium Monoazide-Modified Quantitative PCR

(2016) Yu Luo et al.   CHEMBIOCHEM

Iminosugar-Cyclopeptoid Conjugates Raise Multivalent Effect in Glycosidase Inhibition at Unprecedented High Levels

(2016) Mathieu L. Lepage et al.   CHEMISTRY-A EUROPEAN JOURNAL

Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities

(2016) Nina Bionda et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Biaryl amide compounds reduce the inflammatory response in macrophages by regulating Dectin-1

(2016) Kyeong Eun Hyung et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Biomedical applications of nisin

(2016) J.M. Shin et al.   JOURNAL OF APPLIED MICROBIOLOGY

Cyclization Improves Membrane Permeation by Antimicrobial Peptoids

(2016) Konstantin Andreev et al.   LANGMUIR

Synthesis and complexing properties of cyclic benzylopeptoids – a new family of extended macrocyclic peptoids

(2016) A. Meli et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Enlarging the chemical space of anti-leishmanials: a structure–activity relationship study of peptoids against Leishmania mexicana, a causative agent of cutaneous leishmaniasis

(2016) H. L. Bolt et al.   MedChemComm

Lysine-rich Cyclotides: A New Subclass of Circular Knotted Proteins from Violaceae

(2015) Anjaneya S. Ravipati et al.   ACS Chemical Biology

A Chemical Inhibitor of the Skp2/p300 Interaction that Promotes p53-Mediated Apoptosis

(2015) Misook Oh et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of antibacterial 1,3-diyne-linked peptoids from an Ugi-4CR/Glaser coupling approach

(2015) Martin C N Brauer et al.   Beilstein Journal of Organic Chemistry

The efficacy of trivalent cyclic hexapeptides to induce lipid clustering in PG/PE membranes correlates with their antimicrobial activity

(2015) Sebastian Finger et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Peptide therapeutics: current status and future directions

(2015) Keld Fosgerau et al.   DRUG DISCOVERY TODAY

Synthesis and Antiproliferative Activity Evaluation of the Disulfide-Containing Cyclic Peptide Thiochondrilline C and Derivatives

(2015) Mohana Rao Vippila et al.   JOURNAL OF NATURAL PRODUCTS

Poly(α-Peptoid)s Revisited: Synthesis, Properties, and Use as Biomaterial

(2015) Christian Secker et al.   MACROMOLECULAR BIOSCIENCE

A Facile Strategy for the Construction of Cyclic Peptoids under Microwave Irradiation through a Simple Substitution Reaction

(2015) Prathap Jeya Kaniraj et al.   ORGANIC LETTERS

Targeting DnaN for tuberculosis therapy using novel griselimycins

(2015) A. Kling et al.   SCIENCE

Facile Solid-Phase Parallel Synthesis of Linear and Cyclic Peptoids for Comparative Studies of Biological Activity

(2015) Shinae Park et al.   ACS Combinatorial Science

Covalent Attachment of Cyclic TAT Peptides to GFP Results in Protein Delivery into Live Cells with Immediate Bioavailability

(2014) Nicole Nischan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of the first examples of iminosugar clusters based on cyclopeptoid cores

(2014) Mathieu L Lepage et al.   Beilstein Journal of Organic Chemistry

Macrocyclic arylopeptoids – a novel type of cyclic N-alkylated aromatic oligoamides forming nanotubular assemblies

(2014) Thomas Hjelmgaard et al.   CHEMICAL COMMUNICATIONS

Peptidomimetics via modifications of amino acids and peptide bonds

(2014) Ilker Avan et al.   CHEMICAL SOCIETY REVIEWS

Investigating the Anti-leishmanial Effects of Linear Peptoids

(2014) Gabriela A. Eggimann et al.   ChemMedChem

Orthogonal Protection of Peptides and Peptoids for Cyclization by the Thiol–Ene Reaction and Conjugation

(2014) Xavier Elduque et al.   JOURNAL OF ORGANIC CHEMISTRY

Facile Method To Sequence Cyclic Peptides/Peptoids via One-Pot Ring-Opening/Cleavage Reaction

(2014) Kang Ju Lee et al.   ORGANIC LETTERS

Small Head-to-Tail Macrocyclic α-Peptoids

(2014) Adrian S. Culf et al.   ORGANIC LETTERS

New cyclic RGD peptides: synthesis, characterization, and theoretical activity towards αvβ3 integrin

(2014) Helena Vilaça et al.   TETRAHEDRON

Peptoid nanotubes: an oligomer macrocycle that reversibly sequesters water via single-crystal-to-single-crystal transformations

(2013) Sidonie B. L. Vollrath et al.   CHEMICAL COMMUNICATIONS

Synthesis, biological activity and resistance to proteolytic digestion of new cyclic dermorphin/deltorphin analogues

(2013) Krzysztof Bańkowski et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Amphiphilic Cyclic Peptoids That Exhibit Antimicrobial Activity by DisruptingStaphylococcus aureusMembranes

(2013) Mia L. Huang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Cis–Trans Amide Bond Rotamers in β-Peptoids and Peptoids: Evaluation of Stereoelectronic Effects in Backbone and Side Chains

(2013) Jonas S. Laursen et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis of Boron-Containing Primary Amines

(2013) Sheng-Hsuan Chung et al.   MOLECULES

Gadolinium-binding cyclic hexapeptoids: synthesis and relaxometric properties

(2013) Chiara De Cola et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cyclic α,β-Tetrapeptoids: Sequence-Dependent Cyclization and Conformational Preference

(2013) Cécile Caumes et al.   ORGANIC LETTERS

Antibiotic development challenges: the various mechanisms of action of antimicrobial peptides and of bacterial resistance

(2013) Fernanda Guilhelmelli et al.   Frontiers in Microbiology

Design of Peptide Imaging Agents for Whole-body and Intraoperative Molecular Imaging

(2012) J. A. Moss et al.   CURRENT MEDICINAL CHEMISTRY

Cyclopeptoids: a novel class of phase-transfer catalysts

(2012) Giorgio Della Sala et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Twice tied tight: Enforcing conformational order in bicyclic peptoid oligomers

(2012) Sidonie B. L. Vollrath et al.   Chemical Science

Macrocyclic Peptoid–Peptide Hybrids as Inhibitors of Class I Histone Deacetylases

(2012) Christian A. Olsen et al.   ACS Medicinal Chemistry Letters

Cyclic RGD Functionalized Gold Nanoparticles for Tumor Targeting

(2011) Daniela Arosio et al.   BIOCONJUGATE CHEMISTRY

A Comparison of Linear and Cyclic Peptoid Oligomers as Potent Antimicrobial Agents

(2011) Mia Lace Huang et al.   ChemMedChem

Multicomponent synthesis of acylated short peptoids with antifungal activity against plant pathogens

(2011) Matías D. Galetti et al.   MOLECULAR DIVERSITY

Fast and efficient microwave-assisted synthesis of functionalized peptoids via Ugi reactions

(2011) Angélica de Fátima S. Barreto et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Design and Facile Solid-Phase Synthesis of Conformationally Constrained Bicyclic Peptoids

(2011) Ji Hoon Lee et al.   ORGANIC LETTERS

Ring-Closing Metathesis Approaches for the Solid-Phase Synthesis of Cyclic Peptoids

(2011) Sharaf Nawaz Khan et al.   ORGANIC LETTERS

Thiol-Ene Click Chemistry

(2010) Charles E. Hoyle et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Design, synthesis and antimicrobial properties of non-hemolytic cationic α-cyclopeptoids

(2010) Daniela Comegna et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Towards Design of Novel Antimicrobial Agents: Role of the Conformational Rigidity

(2010) Andrey Ivankin et al.   BIOPHYSICAL JOURNAL

Peptoid origins

(2010) Ronald N. Zuckermann   BIOPOLYMERS

A simple strategy for the construction of combinatorial cyclic peptoid libraries

(2010) Ji Hoon Lee et al.   CHEMICAL COMMUNICATIONS

Peptoid Macrocycles: Making the Rounds with Peptidomimetic Oligomers

(2010) Barney Yoo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Macrocyclic Histone Deacetylase Inhibitors

(2010) Sandra C. Mwakwari et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Peptide-mediated targeted drug delivery

(2010) Sumit Majumdar et al.   MEDICINAL RESEARCH REVIEWS

Multifaceted polo-like kinases: drug targets and antitargets for cancer therapy

(2010) Klaus Strebhardt   NATURE REVIEWS DRUG DISCOVERY

Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group

(2009) Vishal Patil et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Structure–function relationships in peptoids: Recent advances toward deciphering the structural requirements for biological function

(2009) Sarah A. Fowler et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Cell-penetrating and cell-targeting peptides in drug delivery

(2008) Eric Vivès et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Synthesis, structures, and properties of nine-, twelve-, and eighteen-membered N-benzyloxyethyl cyclic α-peptoids

(2008) N. Maulucci et al.   CHEMICAL COMMUNICATIONS

Oligo(N-aryl glycines): A New Twist on Structured Peptoids

(2008) Neel H. Shah et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cyclic β-Peptoids

(2008) Olivier Roy et al.   ORGANIC LETTERS

Design and Synthesis of Macrocyclic Peptomers as Mimics of a Quorum Sensing Signal fromStaphylococcus aureus

(2008) Sarah A. Fowler et al.   ORGANIC LETTERS

Design and Synthesis of Cyclic RGD Pentapeptoids by Consecutive Ugi Reactions

(2007) Otilie E. Vercillo et al.   ORGANIC LETTERS