A Chemical Inhibitor of the Skp2/p300 Interaction that Promotes p53-Mediated Apoptosis

A Reversible and Highly Selective Inhibitor of the Proteasomal Ubiquitin Receptor Rpn13 Is Toxic to Multiple Myeloma Cells

(2015) Darci J. Trader et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modulators of Protein–Protein Interactions

(2014) Lech-Gustav Milroy et al.   CHEMICAL REVIEWS

Small-Molecule Inhibitors of Protein-Protein Interactions: Progressing toward the Reality

(2014) Michelle R. Arkin et al.   CHEMISTRY & BIOLOGY

SCF ubiquitin ligase-targeted therapies

(2014) Jeffrey R. Skaar et al.   NATURE REVIEWS DRUG DISCOVERY

Facile Method To Sequence Cyclic Peptides/Peptoids via One-Pot Ring-Opening/Cleavage Reaction

(2014) Kang Ju Lee et al.   ORGANIC LETTERS

Potential pharmacological chaperones targeting cancer-associated MCL-1 and Parkinson disease-associated  -synuclein

(2014) M. Oh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pharmacological Inactivation of Skp2 SCF Ubiquitin Ligase Restricts Cancer Stem Cell Traits and Cancer Progression

(2013) Chia-Hsin Chan et al.   CELL

Screening Bicyclic Peptide Libraries for Protein–Protein Interaction Inhibitors: Discovery of a Tumor Necrosis Factor-α Antagonist

(2013) Wenlong Lian et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Targeting protein–protein interactions as an anticancer strategy

(2013) Andrei A. Ivanov et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Rational Design of Bioactive, Modularly Assembled Aminoglycosides Targeting the RNA that Causes Myotonic Dystrophy Type 1

(2012) Jessica L. Childs-Disney et al.   ACS Chemical Biology

Acetylation-Dependent Regulation of Skp2 Function

(2012) Hiroyuki Inuzuka et al.   CELL

The Skp2-SCF E3 Ligase Regulates Akt Ubiquitination, Glycolysis, Herceptin Sensitivity, and Tumorigenesis

(2012) Chia-Hsin Chan et al.   CELL

Structural Biology and Drug Discovery of Difficult Targets: The Limits of Ligandability

(2012) Sachin Surade et al.   CHEMISTRY & BIOLOGY

Specific Small Molecule Inhibitors of Skp2-Mediated p27 Degradation

(2012) Lily Wu et al.   CHEMISTRY & BIOLOGY

Peptoids: Bio-Inspired Polymers as Potential Pharmaceuticals

(2012) Michelle T. Dohm et al.   CURRENT PHARMACEUTICAL DESIGN

Identification of Candidate IgG Biomarkers for Alzheimer's Disease via Combinatorial Library Screening

(2011) M. Muralidhar Reddy et al.   CELL

Design and Facile Solid-Phase Synthesis of Conformationally Constrained Bicyclic Peptoids

(2011) Ji Hoon Lee et al.   ORGANIC LETTERS

A simple strategy for the construction of combinatorial cyclic peptoid libraries

(2010) Ji Hoon Lee et al.   CHEMICAL COMMUNICATIONS

Peptoid Macrocycles: Making the Rounds with Peptidomimetic Oligomers

(2010) Barney Yoo et al.   CHEMISTRY-A EUROPEAN JOURNAL

Targeting the p27 E3 ligase SCFSkp2 results in p27- and Skp2-mediated cell-cycle arrest and activation of autophagy

(2008) Q. Chen et al.   BLOOD

Oncogenic properties and prognostic implications of the ubiquitin ligase Skp2 in cancer

(2008) Dan D. Hershko   CANCER

Peptoid architectures: elaboration, actuation, and application

(2008) Barney Yoo et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Skp2 Suppresses p53-Dependent Apoptosis by Inhibiting p300

(2008) Mayumi Kitagawa et al.   MOLECULAR CELL