Journal
FOOD AND AGRICULTURAL IMMUNOLOGY
Volume 26, Issue 5, Pages 682-689Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/09540105.2015.1007448
Keywords
total complement; classical swine fever antibody; immunoglobulin; antibacterial peptide; weaned piglets
Funding
- Changjiang Scholars & Innovative Research Team of Ministry of Education of China Funds [IRTO848]
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The aim of this study was to investigate the effects of dietary antimicrobial peptide (AMP) supplementation on the serum IgG, IgM, IgA, classical swine fever antibody (CSF-Ab), and total complement (CH50) levels in weaned piglets. Ninety weaned piglets were randomly allotted to five groups for 28-day study. Blood samples were collected at 32, 39, 46, and 53 days of age. The results showed that AMP as dietary additive increased the levels of IgG, IgM, IgA, CSF-Ab, CH50 among the whole experimental period, and the effects of AMP supplementation were dose-dependent. The study showed that supplementing weaned piglets diets with AMP enhanced the humoral immune responses of weaned piglets by improving the levels of classical swine fever virus antibody, CH50, and immunoglobulins. We suggest the dosage of AMP was 500 mg/kg.
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