Protecting-Group-Free Amidation of Amino Acids using Lewis Acid Catalysts

Mechanistic insights into boron-catalysed direct amidation reactions

(2018) Sergey Arkhipenko et al.   Chemical Science

Unique physicochemical and catalytic properties dictated by the B3NO2 ring system

(2017) Hidetoshi Noda et al.   Nature Chemistry

Borate esters: Simple catalysts for the sustainable synthesis of complex amides

(2017) Marco T. Sabatini et al.   Science Advances

On the design of complex drug candidate syntheses in the pharmaceutical industry

(2017) Martin D. Eastgate et al.   Nature Reviews Chemistry

Direct amidation of unprotected amino acids using B(OCH2CF3)3

(2016) Rachel M. Lanigan et al.   CHEMICAL COMMUNICATIONS

Comparing Amide-Forming Reactions Using Green Chemistry Metrics in an Undergraduate Organic Laboratory

(2016) Michael W. Fennie et al.   JOURNAL OF CHEMICAL EDUCATION

The application of design of experiments (DoE) reaction optimisation and solvent selection in the development of new synthetic chemistry

(2016) Paul M. Murray et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Large-Scale Applications of Amide Coupling Reagents for the Synthesis of Pharmaceuticals

(2016) Joshua R. Dunetz et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Boronic acid–DMAPO cooperative catalysis for dehydrative condensation between carboxylic acids and amines

(2016) Kazuaki Ishihara et al.   Chemical Science

A multigram-scale lower E-factor procedure for MIBA-catalyzed direct amidation and its application to the coupling of alpha and beta aminoacids

(2015) Solmaz Fatemi et al.   GREEN CHEMISTRY

B(OCH2CF3)3-mediated direct amidation of pharmaceutically relevant building blocks in cyclopentyl methyl ether

(2015) Valerija Karaluka et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A General Method for Imine Formation Using B(OCH2CF3)3

(2015) Jonathan T. Reeves et al.   ORGANIC LETTERS

Development of a Two-Step, Enantioselective Synthesis of an Amino Alcohol Drug Candidate

(2015) Michael A. Schmidt et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Hafnium-Catalyzed Direct Amide Formation at Room Temperature

(2015) Helena Lundberg et al.   ACS Catalysis

Total Synthesis of Tricladins A and B and Identification of Their Absolute Configuration

(2014) He Zhao et al.   JOURNAL OF ORGANIC CHEMISTRY

Recent Developments in Amide Synthesis: Direct Amidation of Carboxylic Acids and Transamidation Reactions

(2013) Rachel M. Lanigan et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Direct Synthesis of Amides from Carboxylic Acids and Amines Using B(OCH2CF3)3

(2013) Rachel M. Lanigan et al.   JOURNAL OF ORGANIC CHEMISTRY

Convenient primary amidation of N-protected phenylglycine and dipeptides without racemization or epimerization

(2013) Takuya Noguchi et al.   TETRAHEDRON LETTERS

Direct Amide Coupling of Non-activated Carboxylic Acids and Amines Catalysed by Zirconium(IV) Chloride

(2012) Helena Lundberg et al.   CHEMISTRY-A EUROPEAN JOURNAL

Direct Amidation of Carboxylic Acids Catalyzed by ortho-Iodo Arylboronic Acids: Catalyst Optimization, Scope, and Preliminary Mechanistic Study Supporting a Peculiar Halogen Acceleration Effect

(2012) Nicolas Gernigon et al.   JOURNAL OF ORGANIC CHEMISTRY

Direct amide formation from unactivated carboxylic acids and amines

(2011) C. Liana Allen et al.   CHEMICAL COMMUNICATIONS

Lacosamide as adjunctive therapy for partial-onset epileptic seizures: a review of the clinical and economic literature

(2011) Steven Simoens   CURRENT MEDICAL RESEARCH AND OPINION

Primary Amino Acid Derivatives: Compounds with Anticonvulsant and Neuropathic Pain Protection Activities

(2011) Amber M. King et al.   JOURNAL OF MEDICINAL CHEMISTRY

Rethinking amide bond synthesis

(2011) Vijaya R. Pattabiraman et al.   NATURE

Borate esters as convenient reagents for direct amidation of carboxylic acids and transamidation of primary amides

(2010) Pavel Starkov et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Direct and Waste-Free Amidations and Cycloadditions by Organocatalytic Activation of Carboxylic Acids at Room Temperature

(2008) Raed M. Al-Zoubi et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Asymmetric Direct Amide Synthesis by Kinetic Amine Resolution: A Chiral Bifunctional Aminoboronic Acid Catalyzed Reaction between a Racemic Amine and an Achiral Carboxylic Acid

(2008) Kenny Arnold et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis and anticonvulsant activities of N-benzyl (2R)-2-acetamido-3-oxysubstituted propionamide derivatives

(2008) Pierre Morieux et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Dehydrative condensation catalyses

(2008) Kazuaki Ishihara   TETRAHEDRON