Late-Stage Functionalization of Arylacetic Acids by Photoredox-Catalyzed Decarboxylative Carbon-Heteroatom Bond Formation

Organic synthesis provides opportunities to transform drug discovery

(2018) David C. Blakemore et al.   Nature Chemistry

Hypervalent Iodine(III)-Mediated Decarboxylative Ritter-Type Amination Leading to the Production of α-Tertiary Amine Derivatives

(2017) Kensuke Kiyokawa et al.   JOURNAL OF ORGANIC CHEMISTRY

Photoinduced, Copper-Catalyzed Decarboxylative C–N Coupling to Generate Protected Amines: An Alternative to the Curtius Rearrangement

(2017) Wei Zhao et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition-Metal-Free Decarboxylative Iodination: New Routes for Decarboxylative Oxidative Cross-Couplings

(2017) Gregory J. P. Perry et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Room temperature decarboxylative cyanation of carboxylic acids using photoredox catalysis and cyanobenziodoxolones: a divergent mechanism compared to alkynylation

(2017) Franck Le Vaillant et al.   Chemical Science

Photo-induced oxidant-free oxidative C–H/N–H cross-coupling between arenes and azoles

(2017) Linbin Niu et al.   Nature Communications

Visible-Light Photoredox Decarboxylative Couplings

(2017) Yunhe Jin et al.   Asian Journal of Organic Chemistry

Catalytic Dehydrogenative C–H Imidation of Arenes Enabled by Photo-generated Hole Donation to Sulfonimide

(2017) Eri Ito et al.   Chem

Catalytic Carbocation Generation Enabled by the Mesolytic Cleavage of Alkoxyamine Radical Cations

(2016) Qilei Zhu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Copper(i)-catalyzed radical decarboxylative imidation of carboxylic acids with N-fluoroarylsulfonimides

(2016) Zhongxue Fang et al.   CHEMICAL COMMUNICATIONS

Decarboxylative Aminomethylation of Aryl- and Vinylsulfonates through Combined Nickel- and Photoredox-Catalyzed Cross-Coupling

(2016) Lulu Fan et al.   CHEMISTRY-A EUROPEAN JOURNAL

Visible Light-Promoted Decarboxylative Di- and Trifluoromethylthiolation of Alkyl Carboxylic Acids

(2016) Lisa Candish et al.   CHEMISTRY-A EUROPEAN JOURNAL

Catalytic Access to Alkyl Bromides, Chlorides and Iodides via Visible Light-Promoted Decarboxylative Halogenation

(2016) Lisa Candish et al.   CHEMISTRY-A EUROPEAN JOURNAL

Photocatalytic Aminodecarboxylation of Carboxylic Acids

(2016) Simon B. Lang et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Ambient Decarboxylative Arylation of Malonate Half-Esters via Oxidative Catalysis

(2016) Patrick J. Moon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Visible-Light-Mediated Synthesis of Amidyl Radicals: Transition-Metal-Free Hydroamination and N-Arylation Reactions

(2016) Jacob Davies et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Amide-directed photoredox-catalysed C–C bond formation at unactivated sp3 C–H bonds

(2016) John C. K. Chu et al.   NATURE

Metallaphotoredox-catalysed sp3–sp3 cross-coupling of carboxylic acids with alkyl halides

(2016) Craig P. Johnston et al.   NATURE

Catalytic alkylation of remote C–H bonds enabled by proton-coupled electron transfer

(2016) Gilbert J. Choi et al.   NATURE

Asymmetric copper-catalyzed C-N cross-couplings induced by visible light

(2016) Q. M. Kainz et al.   SCIENCE

Donor–Acceptor Fluorophores for Visible-Light-Promoted Organic Synthesis: Photoredox/Ni Dual Catalytic C(sp3)–C(sp2) Cross-Coupling

(2016) Jian Luo et al.   ACS Catalysis

Radical Decarboxylative Functionalizations Enabled by Dual Photoredox Catalysis

(2016) Hanchu Huang et al.   ACS Catalysis

Visible-Light-Induced Decarboxylative Functionalization of Carboxylic Acids and Their Derivatives

(2015) Jun Xuan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Mechanistic Study of Silver-Catalyzed Decarboxylative Fluorination

(2015) Niki R. Patel et al.   JOURNAL OF ORGANIC CHEMISTRY

Bond-Weakening Catalysis: Conjugate Aminations Enabled by the Soft Homolysis of Strong N–H Bonds

(2015) Kyle T. Tarantino et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Decarboxylative Fluorination of Aliphatic Carboxylic Acids via Photoredox Catalysis

(2015) Sandrine Ventre et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Site-selective arene C-H amination via photoredox catalysis

(2015) N. A. Romero et al.   SCIENCE

Visible-light-mediated decarboxylative benzoyloxylation of β-hydroxy amino acids and its application to synthesis of functional 1,2-amino alcohol derivatives

(2015) Shinsuke Inuki et al.   TETRAHEDRON LETTERS

Visible-Light-Mediated Decarboxylation/Oxidative Amidation of α-Keto Acids with Amines under Mild Reaction Conditions Using O2

(2013) Jie Liu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Silver-Catalyzed Decarboxylative Chlorination of Aliphatic Carboxylic Acids

(2012) Zhentao Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Silver-Catalyzed Decarboxylative Fluorination of Aliphatic Carboxylic Acids in Aqueous Solution

(2012) Feng Yin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Transition Metal-Catalyzed Decarboxylative Allylation and Benzylation Reactions

(2011) Jimmie D. Weaver et al.   CHEMICAL REVIEWS

Decarboxylative coupling reactions: a modern strategy for C–C-bond formation

(2011) Nuria Rodríguez et al.   CHEMICAL SOCIETY REVIEWS

Synopsis of Some Recent Tactical Application of Bioisosteres in Drug Design

(2011) Nicholas A. Meanwell   JOURNAL OF MEDICINAL CHEMISTRY

Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality

(2009) Ellen M. Sletten et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The Barton ester free-radical reaction: a brief review of applications

(2009) Maurício F. Saraiva et al.   TETRAHEDRON