Substitution-Inert Polynuclear Platinum Complexes as Metalloshielding Agents for Heparan Sulfate

Antiangiogenic platinum through glycan targeting

(2017) Erica J. Peterson et al.   Chemical Science

Exploring Bacterial Heparinase II Activities with Defined Substrates

(2015) Lisa Bohlmann et al.   CHEMBIOCHEM

Multi-platinum anti-cancer agents. Substitution-inert compounds for tumor selectivity and new targets

(2015) N. P. Farrell   CHEMICAL SOCIETY REVIEWS

Solution studies on DNA interactions of substitution-inert platinum complexes mediated via the phosphate clamp

(2015) Y. Qu et al.   DALTON TRANSACTIONS

Heparin/Heparan Sulfate Proteoglycans Glycomic Interactome in Angiogenesis: Biological Implications and Therapeutical Use

(2015) Paola Chiodelli et al.   MOLECULES

The potential of heparanase as a therapeutic target in cancer

(2014) Claudio Pisano et al.   BIOCHEMICAL PHARMACOLOGY

A new approach to glycan targeting: enzyme inhibition by oligosaccharide metalloshielding

(2014) John B. Mangrum et al.   CHEMICAL COMMUNICATIONS

Nucleolar Targeting by Platinum: p53-Independent Apoptosis Follows rRNA Inhibition, Cell-Cycle Arrest, and DNA Compaction

(2014) Erica J. Peterson et al.   MOLECULAR PHARMACEUTICS

The phosphate clamp: sequence selective nucleic acid binding profiles and conformational induction of endonuclease inhibition by cationic Triplatin complexes

(2014) Andreea Prisecaru et al.   NUCLEIC ACIDS RESEARCH

1H NMR spectroscopic studies establish that heparanase is a retaining glycosidase

(2013) Jennifer C. Wilson et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cooperative Heparin-Mediated Oligomerization of Fibroblast Growth Factor-1 (FGF1) Precedes Recruitment of FGFR2 to Ternary Complexes

(2013) Alan Brown et al.   BIOPHYSICAL JOURNAL

Complete Mass Spectral Characterization of a Synthetic Ultralow-Molecular-Weight Heparin Using Collision-Induced Dissociation

(2012) Muchena J. Kailemia et al.   ANALYTICAL CHEMISTRY

Discovery of PG545: A Highly Potent and Simultaneous Inhibitor of Angiogenesis, Tumor Growth, and Metastasis

(2012) Vito Ferro et al.   JOURNAL OF MEDICINAL CHEMISTRY

Heparan Sulfate Proteoglycan-Mediated Entry Pathway for Charged Tri-Platinum Compounds: Differential Cellular Accumulation Mechanisms for Platinum

(2012) Heveline Silva et al.   MOLECULAR PHARMACEUTICS

SST0001, a Chemically Modified Heparin, Inhibits Myeloma Growth and Angiogenesis via Disruption of the Heparanase/Syndecan-1 Axis

(2011) Joseph P. Ritchie et al.   CLINICAL CANCER RESEARCH

Drug transporters of platinum-based anticancer agents and their clinical significance

(2011) Herman Burger et al.   DRUG RESISTANCE UPDATES

Influence of Heparin Mimetics on Assembly of the FGF·FGFR4 Signaling Complex

(2010) Krishna Saxena et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A [polycation:heparin] complex releases growth factors with enhanced bioactivity

(2010) Hunghao Chu et al.   JOURNAL OF CONTROLLED RELEASE

Copper Transporters and the Cellular Pharmacology of the Platinum-Containing Cancer Drugs

(2010) S. B. Howell et al.   MOLECULAR PHARMACOLOGY

Development of a colorimetric assay for heparanase activity suitable for kinetic analysis and inhibitor screening

(2009) Edward Hammond et al.   ANALYTICAL BIOCHEMISTRY

Analysis of Cooperativity by Isothermal Titration Calorimetry

(2009) Alan Brown   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Role of Cellular Accumulation in Determining Sensitivity to Platinum-Based Chemotherapy

(2007) Matthew D. Hall et al.   Annual Review of Pharmacology and Toxicology