Nucleophilic β-Carbon Activation of Propionic Acid as a 3-Carbon Synthon by Carbene Organocatalysis

Ferrocene-Based Planar Chiral Imidazopyridinium Salts for Catalysis

(2015) Christopher T. Check et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic carbene-catalyzed enantioselective annulations: a dual activation strategy for a formal [4+2] addition for dihydrocoumarins

(2015) Anna Lee et al.   CHEMICAL COMMUNICATIONS

An NHC-Catalyzed In Situ Activation Strategy to β-Functionalize Saturated Carboxylic Acid: An Enantioselective Formal [3+2] Annulation for Spirocyclic Oxindolo-γ-butyrolactones

(2015) Yuanwei Xie et al.   CHEMISTRY-A EUROPEAN JOURNAL

Stereoselective Lewis base catalyzed formal 1,3-dipolar cycloaddition of azomethine imines with mixed anhydrides

(2015) Lena Hesping et al.   Chemical Science

On the Mechanism of N-Heterocyclic Carbene-Catalyzed Reactions Involving Acyl Azoliums

(2014) Jessada Mahatthananchai et al.   ACCOUNTS OF CHEMICAL RESEARCH

N-Heterocyclic Carbene Catalyzed Activation of Esters: A New Option for Asymmetric Domino Reactions

(2014) Pankaj Chauhan et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Access to Oxoquinoline Heterocycles by N-Heterocyclic Carbene Catalyzed Ester Activation for Selective Reaction with an Enone

(2014) Zhenqian Fu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Cooperative N-Heterocyclic Carbene/Chiral Phosphate Catalysis System for Allenolate Annulations

(2014) Anna Lee et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

β-Functionalization of Carboxylic Anhydrides with β-Alkyl Substituents through Carbene Organocatalysis

(2014) Zhichao Jin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cascade Olefin Isomerization/Intramolecular Diels-Alder Reaction Catalyzed by N-Heterocyclic Carbenes

(2014) Marcin Kowalczyk et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-Heterocyclic Carbene Catalyzed Cyclocondensation of α,β-Unsaturated Carboxylic Acids: Enantioselective Synthesis of Pyrrolidinone and Dihydropyridinone Derivatives

(2014) Xiang-Yu Chen et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Conjugate Umpolung of β,β-Disubstituted Enals by Dual Catalysis with an N-Heterocyclic Carbene and a Brønsted Acid: Facile Construction of Contiguous Quaternary Stereocenters

(2014) Jun-Long Li et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Lewis base functionalisation of carboxylic acids, esters and anhydrides via C1-ammonium or azolium enolates

(2014) Louis C. Morrill et al.   CHEMICAL SOCIETY REVIEWS

Enantioselective All-Carbon (4+2) Annulation by N-Heterocyclic Carbene Catalysis

(2014) Lisa Candish et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioconvergent Synthesis of Functionalized γ-Butyrolactones via (3 + 2)-Annulation

(2014) C. Guy Goodman et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Annulations for Dihydroquinolones by in Situ Generation of Azolium Enolates

(2014) Anna Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

An overview of N-heterocyclic carbenes

(2014) Matthew N. Hopkinson et al.   NATURE

NHC-catalyzed oxidative γ-addition of α,β-unsaturated aldehydes to isatins: a high-efficiency synthesis of spirocyclic oxindole-dihydropyranones

(2014) Rui Liu et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Direct Catalytic Asymmetric Synthesis of N-Heterocycles from Commodity Acid Chlorides by Employing α,β-Unsaturated Acylammonium Salts

(2013) Sreekumar Vellalath et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

N-tert-Butyl Triazolylidenes: Catalysts for the Enantioselective (3+2) Annulation of α,β-Unsaturated Acyl Azoliums

(2013) Lisa Candish et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isothiourea-Mediated One-Pot Synthesis of Functionalized Pyridines

(2013) Daniel G. Stark et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

NHC Organocatalytic Formal LUMO Activation of α,β-Unsaturated Esters for Reaction with Enamides

(2013) Jiajia Cheng et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

1-Thia-4,7-diaza-spiro[4.4]nonane-3,6-dione: A Structural Motif for 5-hydroxytryptamine 6 Receptor Antagonism

(2013) Greg Hostetler et al.   Chemical Biology & Drug Design

Acyl anion free N-heterocyclic carbene organocatalysis

(2013) Sarah J. Ryan et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic Carbene (NHC)-Catalyzed/Lewis Acid Mediated Conjugate Umpolung of Alkynyl Aldehydes for the Synthesis of Butenolides: A Formal [3+2] Annulation

(2013) Jing Qi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Asymmetric Homoenolate Additions to Acyl Phosphonates through Rational Design of a Tailored N-Heterocyclic Carbene Catalyst

(2013) Ki Po Jang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

β-Carbon activation of saturated carboxylic esters through N-heterocyclic carbene organocatalysis

(2013) Zhenqian Fu et al.   Nature Chemistry

Organocatalytic Activation of Alkylacetic Esters as Enolate Precursors to React with α,β-Unsaturated Imines

(2013) Lin Hao et al.   ORGANIC LETTERS

Asymmetric Access to the Smallest Enolate Intermediate via Organocatalytic Activation of Acetic Ester

(2013) Shaojin Chen et al.   ORGANIC LETTERS

Organocatalytic Enantioselective γ-Aminoalkylation of Unsaturated Ester: Access to Pipecolic Acid Derivatives

(2013) Jianfeng Xu et al.   ORGANIC LETTERS

N-Heterocyclic Carbene Catalyzed Homoenolate-Addition Reaction of Enals and Nitroalkenes: Asymmetric Synthesis of 5-Carbon-Synthon δ-Nitroesters

(2012) Biswajit Maji et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

An N-Heterocyclic Carbene/Lewis Acid Strategy for the Stereoselective Synthesis of Spirooxindole Lactones

(2012) Julien Dugal-Tessier et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dihydropyridones: Catalytic Asymmetric Synthesis, N- to C-Sulfonyl Transfer, and Derivatizations

(2012) Carmen Simal et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Continuum of Progress: Applications of N-Hetereocyclic Carbene Catalysis in Total Synthesis

(2012) Javier Izquierdo et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Catalytic, enantio- and diastereoselective synthesis of γ-butyrolactones incorporating quaternary stereocentres

(2012) Francesco Manoni et al.   CHEMICAL COMMUNICATIONS

Organocatalytic umpolung: N-heterocyclic carbenes and beyond

(2012) Xavier Bugaut et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic Carbene-Catalyzed Homoenolate Additions with N-Aryl Ketimines as Electrophiles: Efficient Synthesis of Spirocyclic γ-Lactam Oxindoles

(2012) Bo Zhang et al.   CHEMISTRY-A EUROPEAN JOURNAL

N-Heterocyclic Carbene-Catalyzed Ireland–Coates Claisen Rearrangement: Synthesis of Functionalized β-Lactones

(2012) Lisa Candish et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective Activation of Stable Carboxylate Esters as Enolate Equivalents via N-Heterocyclic Carbene Catalysts

(2012) Lin Hao et al.   ORGANIC LETTERS

NHCs in Asymmetric Organocatalysis: Recent Advances in Azolium Enolate Generation and Reactivity

(2012) Andrew Smith et al.   SYNTHESIS-STUTTGART

N-Heterocyclic Carbene-Catalyzed Cyclization of Unsaturated Acyl Chlorides and Ketones

(2011) Li-Tao Shen et al.   ADVANCED SYNTHESIS & CATALYSIS

Employing homoenolates generated by NHC catalysis in carbon–carbon bond-forming reactions: state of the art

(2011) Vijay Nair et al.   CHEMICAL SOCIETY REVIEWS

N-Heterocyclic Carbene-Catalyzed (4 + 2) Cycloaddition/Decarboxylation of Silyl Dienol Ethers with α,β-Unsaturated Acid Fluorides

(2011) Sarah J. Ryan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Organocatalytic Functionalization of Carboxylic Acids: Isothiourea-Catalyzed Asymmetric Intra- and Intermolecular Michael Addition−Lactonizations

(2011) Dorine Belmessieri et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective, Organocatalyzed, Intramolecular Aldol Lactonizations with Keto Acids Leading to Bi- and Tricyclic β-Lactones and Topology-Morphing Transformations

(2010) Carolyn A. Leverett et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Cooperative catalysis by carbenes and Lewis acids in a highly stereoselective route to γ-lactams

(2010) Dustin E. A. Raup et al.   Nature Chemistry

N-Heterocyclic Carbene Catalyzed Transformations of 3-Halopropenals to the Equivalents of β-Acylvinyl Anions

(2010) Yihua Wu et al.   ORGANIC LETTERS

Chiral N-heterocyclic carbene-catalyzed generation of ester enolate equivalents from  , -unsaturated aldehydes for enantioselective Diels-Alder reactions

(2010) J. Kaeobamrung et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Isothiourea-Catalyzed Enantioselective Carboxy Group Transfer

(2009) Caroline Joannesse et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Synthesis of 4′-aryl-2′,3′-dideoxynucleoside analogues

(2009) Artur Jõgi et al.   TETRAHEDRON

Tandem multi-step synthesis of C-carboxyazlactones promoted by N-heterocyclic carbenes

(2008) Craig D. Campbell et al.   CHEMICAL COMMUNICATIONS

Cyclic Ketimines as Superior Electrophiles for NHC-Catalyzed Homoenolate Additions with Broad Scope and Low Catalyst Loadings

(2008) Michael Rommel et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Concise Synthesis of Spirocyclic, Bridged γ-Butyrolactones via Stereospecific, Dyotropic Rearrangements of β-Lactones Involving 1,2-Acyl and δ-Lactone Migrations

(2008) Vikram C. Purohit et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Enantioselective, NHC-Catalyzed Bicyclo-β-Lactam Formation via Direct Annulations of Enals and UnsaturatedN-Sulfonyl Ketimines

(2007) Ming He et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY