IL-33 induces immunosuppressive neutrophils via a type 2 innate lymphoid cell/IL-13/STAT6 axis and protects the liver against injury in LCMV infection-induced viral hepatitis

ILC2s regulate adaptive Th2 cell functions via PD-L1 checkpoint control

(2017) Christian Schwartz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Endogenous IL-33 Deficiency Exacerbates Liver Injury and Increases Hepatic Influx of Neutrophils in Acute Murine Viral Hepatitis

(2017) Virginie Carrière et al.   MEDIATORS OF INFLAMMATION

IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population

(2017) Daniele C. Nascimento et al.   Nature Communications

IL33-mediated ILC2 activation and neutrophil IL5 production in the lung response after severe trauma: A reverse translation study from a human cohort to a mouse trauma model

(2017) Jing Xu et al.   PLOS MEDICINE

Neutrophil heterogeneity: implications for homeostasis and pathogenesis

(2016) C. Silvestre-Roig et al.   BLOOD

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity

(2016) Roger Geiger et al.   CELL

Innate immunity and inflammation

(2016) Tsan Sam Xiao   Cellular & Molecular Immunology

Host Inflammatory Response to Mosquito Bites Enhances the Severity of Arbovirus Infection

(2016) Marieke Pingen et al.   IMMUNITY

Interleukin-33 facilitates neutrophil recruitment and bacterial clearance in S. aureus-caused peritonitis

(2016) Fang Lan et al.   MOLECULAR IMMUNOLOGY

Group 3 innate lymphoid cells regulate neutrophil migration and function in human decidua

(2016) D Croxatto et al.   Mucosal Immunology

Interleukin 33 is a guardian of barriers and a local alarmin

(2016) Nikolas T Martin et al.   NATURE IMMUNOLOGY

Liver Monocytes and Kupffer Cells Remain Transcriptionally Distinct during Chronic Viral Infection

(2016) Martijn D. B. van de Garde et al.   PLoS One

IL-33 promotes innate IFN-γ production and modulates dendritic cell response in LCMV-induced hepatitis in mice

(2015) Yuejin Liang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Immunological aspects of antiviral therapy of chronic hepatitis B virus and hepatitis C virus infections

(2015) Barbara Rehermann et al.   HEPATOLOGY

Interleukin-33 and Interferon-γ Counter-Regulate Group 2 Innate Lymphoid Cell Activation during Immune Perturbation

(2015) Ari B. Molofsky et al.   IMMUNITY

Exogenous interleukin-33 targets myeloid-derived suppressor cells and generates periphery-induced Foxp3+regulatory T cells in skin-transplanted mice

(2015) Tania Gajardo et al.   IMMUNOLOGY

Neutrophils in viral infections: Current concepts and caveats

(2015) I. E. Galani et al.   JOURNAL OF LEUKOCYTE BIOLOGY

IL-17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis

(2015) Seth B. Coffelt et al.   NATURE

The role of tissue resident cells in neutrophil recruitment

(2015) Nancy D. Kim et al.   TRENDS IN IMMUNOLOGY

γδT Cells Drive Myeloid-Derived Suppressor Cell–Mediated CD8+T Cell Exhaustion in Hepatitis B Virus–Induced Immunotolerance

(2014) Xiaohui Kong et al.   JOURNAL OF IMMUNOLOGY

Intrahepatic Innate Lymphoid Cells Secrete IL-17A and IL-17F That Are Crucial for T Cell Priming in Viral Infection

(2014) Z. Jie et al.   JOURNAL OF IMMUNOLOGY

The alarmin IL-33 promotes regulatory T-cell function in the intestine

(2014) Chris Schiering et al.   NATURE

Immune Suppression by Neutrophils in HIV-1 Infection: Role of PD-L1/PD-1 Pathway

(2014) Nathan L. Bowers et al.   PLoS Pathogens

Neutrophils Recruited to Sites of Infection Protect from Virus Challenge by Releasing Neutrophil Extracellular Traps

(2013) Craig N. Jenne et al.   Cell Host & Microbe

Immune suppression by neutrophils and granulocytic myeloid-derived suppressor cells: similarities and differences

(2013) Janesh Pillay et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Chronic but Not Acute Virus Infection Induces Sustained Expansion of Myeloid Suppressor Cell Numbers that Inhibit Viral-Specific T Cell Immunity

(2013) Brian A. Norris et al.   IMMUNITY

IL-33 Induces Nuocytes and Modulates Liver Injury in Viral Hepatitis

(2013) Y. Liang et al.   JOURNAL OF IMMUNOLOGY

IL-4 and IL-13 employ discrete signaling pathways for target gene expression in alternatively activated monocytes/macrophages

(2012) Ashish Bhattacharjee et al.   FREE RADICAL BIOLOGY AND MEDICINE

IL-33 Priming Regulates Multiple Steps of the Neutrophil-Mediated Anti-Candida albicans Response by Modulating TLR and Dectin-1 Signals

(2012) H. T. Le et al.   JOURNAL OF IMMUNOLOGY

Tissue-Specific Neutrophil Recruitment into the Lung, Liver, and Kidney

(2012) Jan Rossaint et al.   Journal of Innate Immunity

Human suppressive neutrophils CD16bright /CD62Ldim exhibit decreased adhesion

(2012) Vera M. Kamp et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The Alarmin Interleukin-33 Drives Protective Antiviral CD8+ T Cell Responses

(2012) W. V. Bonilla et al.   SCIENCE

IL-33 synergizes with TCR and IL-12 signaling to promote the effector function of CD8+T cells

(2011) Qianting Yang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1

(2011) Janesh Pillay et al.   JOURNAL OF CLINICAL INVESTIGATION

Protective role of IL-33/ST2 axis in Con A-induced hepatitis

(2011) Vladislav Volarevic et al.   JOURNAL OF HEPATOLOGY

IL-33 Expands Suppressive CD11b+ Gr-1int and Regulatory T Cells, including ST2L+ Foxp3+ Cells, and Mediates Regulatory T Cell-Dependent Promotion of Cardiac Allograft Survival

(2011) H. R. Turnquist et al.   JOURNAL OF IMMUNOLOGY

IL-33 induces neutrophil migration in rheumatoid arthritis and is a target of anti-TNF therapy

(2010) W. A. Verri et al.   ANNALS OF THE RHEUMATIC DISEASES

Alternatively activated macrophages inhibit T-cell proliferation by Stat6-dependent expression of PD-L2

(2010) S. Huber et al.   BLOOD

Bone marrow myeloid-derived suppressor cells (MDSCs) inhibit graft-versus-host disease (GVHD) via an arginase-1-dependent mechanism that is up-regulated by interleukin-13

(2010) S. L. Highfill et al.   BLOOD

A Paradoxical Role for Neutrophils in the Pathogenesis of West Nile Virus

(2010) Fengwei Bai et al.   JOURNAL OF INFECTIOUS DISEASES

Interleukin-33 attenuates sepsis by enhancing neutrophil influx to the site of infection

(2010) Jose C Alves-Filho et al.   NATURE MEDICINE

Arginase: an emerging key player in the mammalian immune system

(2009) Markus Munder   BRITISH JOURNAL OF PHARMACOLOGY

Reduction in Neutrophil Count During Hepatitis C Treatment: Drug Toxicity or Predictor of Good Response?

(2009) Gerardo Alvarez-Uria et al.   DIGESTIVE DISEASES AND SCIENCES

Local Suppression of T Cell Responses by Arginase-Induced L-Arginine Depletion in Nonhealing Leishmaniasis

(2009) Manuel Modolell et al.   PLoS Neglected Tropical Diseases