Enhanced metastatic capacity of breast cancer cells after interaction and hybrid formation with mesenchymal stroma/stem cells (MSC)

Cancer stem cell niche models and contribution by mesenchymal stroma/stem cells

(2017) Catharina Melzer et al.   Molecular Cancer

Breast Carcinoma: From Initial Tumor Cell Detachment to Settlement at Secondary Sites

(2017) Catharina Melzer et al.   Biomed Research International

Reduction in Migratory Phenotype in a Metastasized Breast Cancer Cell Line via Downregulation of S100A4 and GRM3

(2017) Andy Chen et al.   Scientific Reports

SCCOHT tumors acquire chemoresistance and protection by interacting mesenchymal stroma/stem cells within the tumor microenvironment

(2016) Anna Otte et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Damage-associated molecular patterns in cancer: a double-edged sword

(2016) C Hernandez et al.   ONCOGENE

Single-cell RNA-seq reveals activation of unique gene groups as a consequence of stem cell-parenchymal cell fusion

(2016) Brian T. Freeman et al.   Scientific Reports

Mesenchymal stem cells generate distinct functional hybrids in vitro via cell fusion or entosis

(2016) Francesco Sottile et al.   Scientific Reports

Massive Clonal Selection and Transiently Contributing Clones During Expansion of Mesenchymal Stem Cell Cultures Revealed by Lentiviral RGB-Barcode Technology

(2016) Anton Selich et al.   Stem Cells Translational Medicine

Cell Fusion Connects Oncogenesis with Tumor Evolution

(2015) Xiaofeng Zhou et al.   AMERICAN JOURNAL OF PATHOLOGY

Apoptosis-induced cancer cell fusion: a mechanism of breast cancer metastasis

(2015) Felicite K. Noubissi et al.   FASEB JOURNAL

Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer

(2015) Xiaofeng Zheng et al.   NATURE

Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

(2015) Kari R. Fischer et al.   NATURE

Human Mesenchymal Stroma/Stem Cells Exchange Membrane Proteins and Alter Functionality During Interaction with Different Tumor Cell Lines

(2015) Yuanyuan Yang et al.   STEM CELLS AND DEVELOPMENT

In vitro and in vivotherapeutic approach for a small cell carcinoma of the ovary hypercalcaemic type using a SCCOHT-1 cellular model

(2014) Anna Otte et al.   Orphanet Journal of Rare Diseases

Tumor Cell Dissemination: Emerging Biological Insights from Animal Models and Cancer Patients

(2013) Yibin Kang et al.   CANCER CELL

The perivascular niche regulates breast tumour dormancy

(2013) Cyrus M. Ghajar et al.   NATURE CELL BIOLOGY

Microenvironmental regulation of tumor progression and metastasis

(2013) Daniela F Quail et al.   NATURE MEDICINE

A Melanoma Brain Metastasis with a Donor-Patient Hybrid Genome following Bone Marrow Transplantation: First Evidence for Fusion in Human Cancer

(2013) Rossitza Lazova et al.   PLoS One

Mesenchymal Stem Cells Directly Interact with Breast Cancer Cells and Promote Tumor Cell Growth In Vitro and In Vivo

(2013) Katharina Mandel et al.   STEM CELLS AND DEVELOPMENT

Genetic basis of cell–cell fusion mechanisms

(2013) Pablo S. Aguilar et al.   TRENDS IN GENETICS

Strange attractors: DAMPs and autophagy link tumor cell death and immunity

(2013) W Hou et al.   Cell Death & Disease

Spontaneous Formation of Tumorigenic Hybrids between Breast Cancer and Multipotent Stromal Cells Is a Source of Tumor Heterogeneity

(2012) Germana Rappa et al.   AMERICAN JOURNAL OF PATHOLOGY

Identification of subpopulations in mesenchymal stem cell-like cultures from human umbilical cord

(2012) Ingrida Majore et al.   Cell Communication and Signaling

Hybrid cells derived from breast epithelial cell/breast cancer cell fusion events show a differential RAF-AKT crosstalk

(2012) Cem Özel et al.   Cell Communication and Signaling

Mesenchymal stem cells as all-round supporters in a normal and neoplastic microenvironment

(2012) Ralf Hass et al.   Cell Communication and Signaling

Immunosuppressive Properties of Mesenchymal Stem Cells: Advances and Applications

(2012) M. P. De Miguel et al.   CURRENT MOLECULAR MEDICINE

A tumor-derived population (SCCOHT-1) as cellular model for a small cell ovarian carcinoma of the hypercalcemic type

(2012) ANNA OTTE et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

MFSD2a, the Syncytin-2 receptor, is important for trophoblast fusion

(2012) C. Toufaily et al.   PLACENTA

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Interaction of tumor cells with the microenvironment

(2011) Hendrik Ungefroren et al.   Cell Communication and Signaling

Different populations and sources of human mesenchymal stem cells (MSC): A comparison of adult and neonatal tissue-derived MSC

(2011) Ralf Hass et al.   Cell Communication and Signaling

The MSC: An Injury Drugstore

(2011) Arnold I. Caplan et al.   Cell Stem Cell

PDGF-D Improves Drug Delivery and Efficacy via Vascular Normalization, But Promotes Lymphatic Metastasis by Activating CXCR4 in Breast Cancer

(2011) J. Liu et al.   CLINICAL CANCER RESEARCH

Mesenchymal stem cells and progenitor cells in connective tissue engineering and regenerative medicine: is there a future for transplantation?

(2011) Andres Hilfiker et al.   LANGENBECKS ARCHIVES OF SURGERY

Characterization of hybrid cells derived from spontaneous fusion events between breast epithelial cells exhibiting stem-like characteristics and breast cancer cells

(2010) Thomas Dittmar et al.   CLINICAL & EXPERIMENTAL METASTASIS

TNFα-exposed Bone Marrow-derived Mesenchymal Stem Cells Promote Locomotion of MDA-MB-231 Breast Cancer Cells through Transcriptional Activation of CXCR3 Ligand Chemokines

(2010) Soon Young Shin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interplay of cAMP and MAPK pathways in hCG secretion and fusogenic gene expression in a trophoblast cell line

(2010) M. Delidaki et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Growth and Differentiation Properties of Mesenchymal Stromal Cell Populations Derived from Whole Human Umbilical Cord

(2010) Ingrida Majore et al.   Stem Cell Reviews and Reports

Optimization of Culture Conditions for the Expansion of Umbilical Cord-Derived Mesenchymal Stem or Stromal Cell-Like Cells Using Xeno-Free Culture Conditions

(2010) Tim Hatlapatka et al.   TISSUE ENGINEERING PART C-METHODS

Invasion of Human Breast Cancer Cells In vivo Requires Both Paracrine and Autocrine Loops Involving the Colony-Stimulating Factor-1 Receptor

(2009) A. Patsialou et al.   CANCER RESEARCH

Chemokine (C-C Motif) Ligand 2 Engages CCR2+Stromal Cells of Monocytic Origin to Promote Breast Cancer Metastasis to Lung and Bone

(2009) Xin Lu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Cellular senescence of human mammary epithelial cells (HMEC) is associated with an altered MMP-7/HB-EGF signaling and increased formation of elastin-like structures

(2009) Catharina Bertram et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Increased expression of galectin-1 is associated with human oral squamous cell carcinoma development

(2009) Zhang   ONCOLOGY REPORTS

The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells

(2008) Sendurai A. Mani et al.   CELL

Mesenchymal Stem Cell-Mediated Immunosuppression Occurs via Concerted Action of Chemokines and Nitric Oxide

(2008) Guangwen Ren et al.   Cell Stem Cell

Myoblasts and macrophages share molecular components that contribute to cell–cell fusion

(2008) Kostandin V. Pajcini et al.   JOURNAL OF CELL BIOLOGY

MUC1 Initiates Src-CrkL-Rac1/Cdc42-Mediated Actin Cytoskeletal Protrusive Motility after Ligating Intercellular Adhesion Molecule-1

(2008) Q. Shen et al.   MOLECULAR CANCER RESEARCH