De novo tetrahydrobiopterin biosynthesis is impaired in the inflammed striatum of parkin(−/−) mice

Neopterin preconditioning prevents inflammasome activation in mammalian astrocytes

(2018) Roberta de Paula Martins et al.   FREE RADICAL BIOLOGY AND MEDICINE

Time-course of striatal Toll-like receptor expression in neurotoxic, environmental and inflammatory rat models of Parkinson's disease

(2017) Kiah McCabe et al.   JOURNAL OF NEUROIMMUNOLOGY

Cytokine profiling in the prefrontal cortex of Parkinson's Disease and Multiple System Atrophy patients

(2017) Rasmus Rydbirk et al.   NEUROBIOLOGY OF DISEASE

Val66Met BDNF polymorphism is associated with Parkinson's disease cognitive impairment

(2016) Vivian Altmann et al.   NEUROSCIENCE LETTERS

Low BDNF is associated with cognitive impairments in patients with Parkinson’s disease

(2016) Yu Wang et al.   PARKINSONISM & RELATED DISORDERS

Parkin maintains mitochondrial levels of the protective Parkinson’s disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10

(2015) G Bertolin et al.   CELL DEATH AND DIFFERENTIATION

Neopterin as a potential cytoprotective brain molecule

(2015) Karina Ghisoni et al.   JOURNAL OF PSYCHIATRIC RESEARCH

Tissue- and Cell-Specific Mitochondrial Defect in Parkin-Deficient Mice

(2014) Maria Damiano et al.   PLoS One

Tetrahydrobiopterin: biochemistry and pathophysiology

(2013) Ernst R. Werner et al.   BIOCHEMICAL JOURNAL

Parkin-Knockout Mice did not Display Increased Vulnerability to Intranasal Administration of 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

(2013) Aderbal S. Aguiar et al.   NEUROTOXICITY RESEARCH

Bit-by-bit autophagic removal of parkin-labelled mitochondria

(2013) Jin-Yi Yang et al.   Nature Communications

Genetics of Parkinson's Disease

(2013) C. Klein et al.   Cold Spring Harbor Perspectives in Medicine

The axonal transport of mitochondria

(2012) W. M. Saxton et al.   JOURNAL OF CELL SCIENCE

PARIS (ZNF746) Repression of PGC-1α Contributes to Neurodegeneration in Parkinson's Disease

(2011) Joo-Ho Shin et al.   CELL

PINK1 and Parkin Target Miro for Phosphorylation and Degradation to Arrest Mitochondrial Motility

(2011) Xinnan Wang et al.   CELL

Exhaustive analysis of BH4 and dopamine biosynthesis genes in patients with Dopa-responsive dystonia

(2009) F. Clot et al.   BRAIN

Parkin Deficiency Delays Motor Decline and Disease Manifestation in a Mouse Model of Synucleinopathy

(2009) Margot Fournier et al.   PLoS One

Peripheral lipopolysaccharide (LPS) challenge promotes microglial hyperactivity in aged mice that is associated with exaggerated induction of both pro-inflammatory IL-1β and anti-inflammatory IL-10 cytokines

(2008) Christopher J. Henry et al.   BRAIN BEHAVIOR AND IMMUNITY

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY

Parkin Deficiency Increases Vulnerability to Inflammation-Related Nigral Degeneration

(2008) T. C. Frank-Cannon et al.   JOURNAL OF NEUROSCIENCE

Basic Research on Dopamine in Parkinson’s Disease and the Discovery of the Nigrostriatal Dopamine Pathway: The View of an Eyewitness

(2008) Oleh Hornykiewicz   Neurodegenerative Diseases