Mesenchymal stromal cell-derived extracellular vesicles: regenerative and immunomodulatory effects and potential applications in sepsis
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Title
Mesenchymal stromal cell-derived extracellular vesicles: regenerative and immunomodulatory effects and potential applications in sepsis
Authors
Keywords
Mesenchymal stromal (stem) cells, Extracellular vesicles, Exosomes, Mesenchymal stromal cell-derived extracellular vesicles, Sepsis
Journal
CELL AND TISSUE RESEARCH
Volume -, Issue -, Pages -
Publisher
Springer Nature
Online
2018-06-28
DOI
10.1007/s00441-018-2871-5
References
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Note: Only part of the references are listed.- Sepsis: frontiers in supportive care, organisation and research
- (2017) Anders Perner et al. INTENSIVE CARE MEDICINE
- Mesenchymal stem cell–derived extracellular vesicles attenuate kidney inflammation
- (2017) Alfonso Eirin et al. KIDNEY INTERNATIONAL
- hucMSC Exosome-Derived GPX1 Is Required for the Recovery of Hepatic Oxidant Injury
- (2017) Yongmin Yan et al. MOLECULAR THERAPY
- Extracellular vesicle docking at the cellular port: Extracellular vesicle binding and uptake
- (2017) Kinsley C. French et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Exosomal miR-146a Contributes to the Enhanced Therapeutic Efficacy of Interleukin-1β-Primed Mesenchymal Stem Cells Against Sepsis
- (2017) Yuxian Song et al. STEM CELLS
- Human Umbilical Cord Mesenchymal Stromal Cells Improve Survival and Bacterial Clearance in Neonatal Sepsis in Rats
- (2017) Yueniu Zhu et al. STEM CELLS AND DEVELOPMENT
- MicroRNA-17–92 Cluster in Exosomes Enhance Neuroplasticity and Functional Recovery After Stroke in Rats
- (2017) Hongqi Xin et al. STROKE
- White Matter Repair After Extracellular Vesicles Administration in an Experimental Animal Model of Subcortical Stroke
- (2017) Laura Otero-Ortega et al. Scientific Reports
- Adipose-derived mesenchymal stem cells modulate CD14++CD16+ expression on monocytes from sepsis patients in vitro via prostaglandin E2
- (2017) Guanguan Qiu et al. Stem Cell Research & Therapy
- Exosomes derived from human menstrual blood-derived stem cells alleviate fulminant hepatic failure
- (2017) Lu Chen et al. Stem Cell Research & Therapy
- The effects of glomerular and tubular renal progenitors and derived extracellular vesicles on recovery from acute kidney injury
- (2017) Andrea Ranghino et al. Stem Cell Research & Therapy
- Mesenchymal Stem Cell-Derived Extracellular Vesicles as Mediators of Anti-Inflammatory Effects: Endorsement of Macrophage Polarization
- (2017) Claudia Lo Sicco et al. Stem Cells Translational Medicine
- Extracellular Vesicles from Bone Marrow-Derived Mesenchymal Stem Cells Improve Survival from Lethal Hepatic Failure in Mice
- (2017) Hiroaki Haga et al. Stem Cells Translational Medicine
- MSC-derived Extracellular Vesicles Attenuate Immune Responses in Two Autoimmune Murine Models: Type 1 Diabetes and Uveoretinitis
- (2017) Taeko Shigemoto-Kuroda et al. Stem Cell Reports
- Effects of Mesenchymal Stem Cell-Derived Exosomes on Experimental Autoimmune Uveitis
- (2017) Lingling Bai et al. Scientific Reports
- Administration of bone marrow stromal cells in sepsis attenuates sepsis-related coagulopathy
- (2016) Lifei Tan et al. ANNALS OF MEDICINE
- Extracellular Vesicles in Cancer: Cell-to-Cell Mediators of Metastasis
- (2016) Annette Becker et al. CANCER CELL
- MSC surface markers (CD44, CD73, and CD90) can identify human MSC-derived extracellular vesicles by conventional flow cytometry
- (2016) Teresa L. Ramos et al. Cell Communication and Signaling
- Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells During Sepsis by Production of Specialized Proresolving Lipid Mediators*
- (2016) Konstantin Tsoyi et al. CRITICAL CARE MEDICINE
- Hepatoprotective effect of exosomes from human-induced pluripotent stem cell–derived mesenchymal stromal cells against hepatic ischemia-reperfusion injury in rats
- (2016) Kate Nong et al. CYTOTHERAPY
- Angiogenic and anti-inflammatory properties of mesenchymal stem cells from cord blood: soluble factors and extracellular vesicles for cell regeneration
- (2016) Tiziana Montemurro et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Conditioned medium of periodontal ligament mesenchymal stem cells exert anti-inflammatory effects in lipopolysaccharide-activated mouse motoneurons
- (2016) Thangavelu Soundara Rajan et al. EXPERIMENTAL CELL RESEARCH
- Exosomes from iPSCs Delivering siRNA Attenuate Intracellular Adhesion Molecule-1 Expression and Neutrophils Adhesion in Pulmonary Microvascular Endothelial Cells
- (2016) Zhihai Ju et al. INFLAMMATION
- Intravenous transplantation of mesenchymal stromal cells has therapeutic effects in a sepsis mouse model through inhibition of septic natural killer cells
- (2016) Wenhua Liu et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Combination of adipose-derived mesenchymal stem cells (ADMSC) and ADMSC-derived exosomes for protecting kidney from acute ischemia–reperfusion injury
- (2016) Kun-Chen Lin et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3)
- (2016) Mervyn Singer et al. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Exosomes secreted from bone marrow-derived mesenchymal stem cells protect the intestines from experimental necrotizing enterocolitis
- (2016) Terrence M. Rager et al. JOURNAL OF PEDIATRIC SURGERY
- Comprehensive Proteomic Analysis of Mesenchymal Stem Cell Exosomes Reveals Modulation of Angiogenesis via Nuclear Factor-KappaB Signaling
- (2016) Johnathon D. Anderson et al. STEM CELLS
- Extracellular Vesicles in Physiology, Pathology, and Therapy of the Immune and Central Nervous System, with Focus on Extracellular Vesicles Derived from Mesenchymal Stem Cells as Therapeutic Tools
- (2016) Sylwia Koniusz et al. Frontiers in Cellular Neuroscience
- Combined Therapy With Adipose-Derived Mesenchymal Stem Cells and Ciprofloxacin Against Acute Urogenital Organ Damage in Rat Sepsis Syndrome Induced by Intrapelvic Injection of Cecal Bacteria
- (2016) Pei-Hsun Sung et al. Stem Cells Translational Medicine
- Treatment With Human Wharton's Jelly-Derived Mesenchymal Stem Cells Attenuates Sepsis-Induced Kidney Injury, Liver Injury, and Endothelial Dysfunction
- (2016) José M. Cóndor et al. Stem Cells Translational Medicine
- Exosomes Derived fromAkt-Modified Human Umbilical Cord Mesenchymal Stem Cells Improve Cardiac Regeneration and Promote Angiogenesis via Activating Platelet-Derived Growth Factor D
- (2016) Jie Ma et al. Stem Cells Translational Medicine
- Exosome Derived From Human Umbilical Cord Mesenchymal Stem Cell Mediates MiR-181c Attenuating Burn-induced Excessive Inflammation
- (2016) Xiao Li et al. EBioMedicine
- Comparative proteomic analysis of extracellular vesicles isolated from porcine adipose tissue-derived mesenchymal stem/stromal cells
- (2016) Alfonso Eirin et al. Scientific Reports
- Trehalose prevents aggregation of exosomes and cryodamage
- (2016) Steffi Bosch et al. Scientific Reports
- Therapeutic Effects of Human Mesenchymal Stem Cell–derived Microvesicles in Severe Pneumonia in Mice
- (2015) Antoine Monsel et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Endothelial cells suppress monocyte activation through secretion of extracellular vesicles containing antiinflammatory microRNAs
- (2015) M.-S. Njock et al. BLOOD
- Immunoregulatory Effects of Mesenchymal Stem Cell-Derived Extracellular Vesicles on T Lymphocytes
- (2015) Andrea Del Fattore et al. CELL TRANSPLANTATION
- Mesenchymal Stem Cell-Derived Exosomes Improve the Microenvironment of Infarcted Myocardium Contributing to Angiogenesis and Anti-Inflammation
- (2015) Xiaomei Teng et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Exosomes secreted from GATA-4 overexpressing mesenchymal stem cells serve as a reservoir of anti-apoptotic microRNAs for cardioprotection
- (2015) Bin Yu et al. INTERNATIONAL JOURNAL OF CARDIOLOGY
- Effect of exosomes derived from multipluripotent mesenchymal stromal cells on functional recovery and neurovascular plasticity in rats after traumatic brain injury
- (2015) Yanlu Zhang et al. JOURNAL OF NEUROSURGERY
- AKI Recovery Induced by Mesenchymal Stromal Cell-Derived Extracellular Vesicles Carrying MicroRNAs
- (2015) F. Collino et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- LPS-preconditioned mesenchymal stromal cells modify macrophage polarization for resolution of chronic inflammation via exosome-shuttled let-7b
- (2015) Dongdong Ti et al. Journal of Translational Medicine
- Chromatographically isolated CD63+CD81+extracellular vesicles from mesenchymal stromal cells rescue cognitive impairments after TBI
- (2015) Dong-ki Kim et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- TMEM16F is required for phosphatidylserine exposure and microparticle release in activated mouse platelets
- (2015) Toshihiro Fujii et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Extracellular Vesicles Secreted by Bone Marrow- and Adipose Tissue-Derived Mesenchymal Stromal Cells Fail to Suppress Lymphocyte Proliferation
- (2015) Ana Valéria Gouveia de Andrade et al. STEM CELLS AND DEVELOPMENT
- Sepsis induces long-term metabolic and mitochondrial muscle stem cell dysfunction amenable by mesenchymal stem cell therapy
- (2015) P. Rocheteau et al. Nature Communications
- Exosomal miR-223 Contributes to Mesenchymal Stem Cell-Elicited Cardioprotection in Polymicrobial Sepsis
- (2015) Xiaohong Wang et al. Scientific Reports
- Non-cultured dermal-derived mesenchymal cells attenuate sepsis induced by cecal ligation and puncture in mice
- (2015) Yu Wang et al. Scientific Reports
- Combination therapy of menstrual derived mesenchymal stem cells and antibiotics ameliorates survival in sepsis
- (2015) Francisca Alcayaga-Miranda et al. Stem Cell Research & Therapy
- Extracellular Vesicles Improve Post-Stroke Neuroregeneration and Prevent Postischemic Immunosuppression
- (2015) Thorsten R. Doeppner et al. Stem Cells Translational Medicine
- Exosomes Derived from Human Umbilical Cord Mesenchymal Stem Cells Relieve Acute Myocardial Ischemic Injury
- (2015) Yuanyuan Zhao et al. Stem Cells International
- Extracellular Vesicles Derived from Bone Marrow Mesenchymal Stem Cells Protect against Experimental Colitis via Attenuating Colon Inflammation, Oxidative Stress and Apoptosis
- (2015) Jia Yang et al. PLoS One
- Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
- (2014) Marina Colombo et al. Annual Review of Cell and Developmental Biology
- Neutrophil-derived microparticles induce myeloperoxidase-mediated damage of vascular endothelial cells
- (2014) Thassila Pitanga et al. BMC CELL BIOLOGY
- Platelet-derived growth factor regulates the secretion of extracellular vesicles by adipose mesenchymal stem cells and enhances their angiogenic potential
- (2014) Tatiana Lopatina et al. Cell Communication and Signaling
- Human mesenchymal stem cell-derived microvesicles modulate T cell response to islet antigen glutamic acid decarboxylase in patients with type 1 diabetes
- (2014) Enrica Favaro et al. DIABETOLOGIA
- MicroRNA and mRNA cargo of extracellular vesicles from porcine adipose tissue-derived mesenchymal stem cells
- (2014) Alfonso Eirin et al. GENE
- Paclitaxel is incorporated by mesenchymal stromal cells and released in exosomes that inhibit in vitro tumor growth: A new approach for drug delivery
- (2014) Luisa Pascucci et al. JOURNAL OF CONTROLLED RELEASE
- MSC-derived exosomes: a novel tool to treat therapy-refractory graft-versus-host disease
- (2014) L Kordelas et al. LEUKEMIA
- Mesenchymal stem cells: immune evasive, not immune privileged
- (2014) James A Ankrum et al. NATURE BIOTECHNOLOGY
- Ischemic Preconditioning Potentiates the Protective Effect of Stem Cells through Secretion of Exosomes by Targeting Mecp2 via miR-22
- (2014) Yuliang Feng et al. PLoS One
- Microvescicles Derived from Mesenchymal Stromal Cells Are Not as Effective as Their Cellular Counterpart in the Ability to Modulate Immune Responses In Vitro
- (2014) Antonella Conforti et al. STEM CELLS AND DEVELOPMENT
- Microvesicles derived from human Wharton’s Jelly mesenchymal stromal cells ameliorate renal ischemia-reperfusion injury in rats by suppressing CX3CL1
- (2014) Xiangyu Zou et al. Stem Cell Research & Therapy
- Mesenchymal stem cell-derived exosomes promote hepatic regeneration in drug-induced liver injury models
- (2014) Cheau Tan et al. Stem Cell Research & Therapy
- Mesenchymal stem cells: mechanisms of potential therapeutic benefit in ARDS and sepsis
- (2014) James Walter et al. Lancet Respiratory Medicine
- Exosomes as Critical Agents of Cardiac Regeneration Triggered by Cell Therapy
- (2014) Ahmed Gamal-Eldin Ibrahim et al. Stem Cell Reports
- Immunomodulatory Potential of Human Adipose Mesenchymal Stem Cells Derived Exosomes on in vitro Stimulated T Cells
- (2014) Rebeca Blazquez et al. Frontiers in Immunology
- A doxorubicin delivery platform using engineered natural membrane vesicle exosomes for targeted tumor therapy
- (2013) Yanhua Tian et al. BIOMATERIALS
- Extracellular vesicles: Exosomes, microvesicles, and friends
- (2013) Graça Raposo et al. JOURNAL OF CELL BIOLOGY
- Extracellular vesicles derived from human bone marrow mesenchymal stem cells promote angiogenesis in a rat myocardial infarction model
- (2013) Suyan Bian et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Mesenchymal Stem Cells Ameliorate Sepsis-associated Acute Kidney Injury in Mice
- (2013) Cong-juan Luo et al. SHOCK
- MiR-133b Promotes Neural Plasticity and Functional Recovery After Treatment of Stroke with Multipotent Mesenchymal Stromal Cells in Rats Via Transfer of Exosome-Enriched Extracellular Particles
- (2013) Hongqi Xin et al. STEM CELLS
- The Toll-like Receptor 3 Ligand, Poly(I:C), Improves Immunosuppressive Function and Therapeutic Effect of Mesenchymal Stem Cells on Sepsis via Inhibiting MiR-143
- (2013) Xiaoyin Zhao et al. STEM CELLS
- Human Mesenchymal Stem Cell Microvesicles for Treatment ofEscherichia coliEndotoxin-Induced Acute Lung Injury in Mice
- (2013) Ying-gang Zhu et al. STEM CELLS
- Mesenchymal Stem Cells Secrete Immunologically Active Exosomes
- (2013) Bin Zhang et al. STEM CELLS AND DEVELOPMENT
- Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro
- (2013) Ying Zhou et al. Stem Cell Research & Therapy
- The changing immune system in sepsis
- (2013) Jonathan S Boomer et al. Virulence
- Mesenchymal stem cell: An efficient mass producer of exosomes for drug delivery
- (2012) Ronne Wee Yeh Yeo et al. ADVANCED DRUG DELIVERY REVIEWS
- Bronchoalveolar lavage fluid exosomes contribute to cytokine and leukotriene production in allergic asthma
- (2012) P. Torregrosa Paredes et al. ALLERGY
- Human mesenchymal stem cells reduce mortality and bacteremia in gram-negative sepsis in mice in part by enhancing the phagocytic activity of blood monocytes
- (2012) Anna Krasnodembskaya et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Exosomes for drug delivery — a novel application for the mesenchymal stem cell
- (2012) Ruenn Chai Lai et al. BIOTECHNOLOGY ADVANCES
- How to replicate the complexity of human sepsis
- (2012) Kent Doi CRITICAL CARE MEDICINE
- Microvesicles derived from mesenchymal stem cells: Potent organelles for induction of tolerogenic signaling
- (2012) Aram Mokarizadeh et al. IMMUNOLOGY LETTERS
- Microvesicles Derived from Mesenchymal Stem Cells Enhance Survival in a Lethal Model of Acute Kidney Injury
- (2012) Stefania Bruno et al. PLoS One
- Transfer of Growth Factor Receptor mRNA Via Exosomes Unravels the Regenerative Effect of Mesenchymal Stem Cells
- (2012) Susanna Tomasoni et al. STEM CELLS AND DEVELOPMENT
- Mesenchymal stem cells enhance survival and bacterial clearance in murineEscherichia colipneumonia
- (2012) Naveen Gupta et al. THORAX
- Female stem cells are superior to males in preserving myocardial function following endotoxemia
- (2011) Mariuxi C. Manukyan et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes
- (2011) A. Montecalvo et al. BLOOD
- The MSC: An Injury Drugstore
- (2011) Arnold I. Caplan et al. Cell Stem Cell
- Intravenous Infusion of Mesenchymal Stem Cells Is Associated With Improved Myocardial Function During Endotoxemia
- (2011) Brent R. Weil et al. SHOCK
- Mesenchymal Stem Cells Reduce Inflammation while Enhancing Bacterial Clearance and Improving Survival in Sepsis
- (2010) Shirley H. J. Mei et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Cell Surface Tetraspanin Tspan8 Contributes to Molecular Pathways of Exosome-Induced Endothelial Cell Activation
- (2010) I. Nazarenko et al. CANCER RESEARCH
- Reactive Bone Marrow Stromal Cells Attenuate Systemic Inflammation via sTNFR1
- (2010) Hiroshi Yagi et al. MOLECULAR THERAPY
- Antibacterial Effect of Human Mesenchymal Stem Cells Is Mediated in Part from Secretion of the Antimicrobial Peptide LL-37
- (2010) Anna Krasnodembskaya et al. STEM CELLS
- Detrimental hemodynamic and inflammatory effects of microparticles originating from septic rats*
- (2009) Satar Mortaza et al. CRITICAL CARE MEDICINE
- Human adult stem cells derived from adipose tissue protect against experimental colitis and sepsis
- (2009) E Gonzalez-Rey et al. GUT
- Mesenchymal Stem Cell-Derived Microvesicles Protect Against Acute Tubular Injury
- (2009) S. Bruno et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Shedding microvesicles: artefacts no more
- (2009) Emanuele Cocucci et al. TRENDS IN CELL BIOLOGY
- Immunomodulation by Mesenchymal Stem Cells: A Potential Therapeutic Strategy for Type 1 Diabetes
- (2008) R. Abdi et al. DIABETES
- Bone marrow stromal cells attenuate sepsis via prostaglandin E2–dependent reprogramming of host macrophages to increase their interleukin-10 production
- (2008) Krisztián Németh et al. NATURE MEDICINE
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