Extracellular matrix glycation and receptor for advanced glycation end-products activation: a missing piece in the puzzle of the association between diabetes and cancer

Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer

(2017) Barbara Chiavarina et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Stimulatory effects of advanced glycation endproducts (AGEs) on fibronectin matrix assembly

(2017) Alexandra K. Pastino et al.   MATRIX BIOLOGY

Mechanisms that drive inflammatory tumor microenvironment, tumor heterogeneity, and metastatic progression

(2017) Li Yang et al.   SEMINARS IN CANCER BIOLOGY

Extracellular matrix component signaling in cancer

(2016) Hinke A.B. Multhaupt et al.   ADVANCED DRUG DELIVERY REVIEWS

AGEs in human lens capsule promote the TGFβ2-mediated EMT of lens epithelial cells: implications for age-associated fibrosis

(2016) Cibin T. Raghavan et al.   AGING CELL

AGEs trigger autophagy in diabetic skin tissues and fibroblasts

(2016) Kan Sun et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Accumulation of the advanced glycation end product carboxymethyl lysine in breast cancer is positively associated with estrogen receptor expression and unfavorable prognosis in estrogen receptor-negative cases

(2016) Norbert Nass et al.   HISTOCHEMISTRY AND CELL BIOLOGY

Diabetes-associated cardiac fibrosis: Cellular effectors, molecular mechanisms and therapeutic opportunities

(2016) Ilaria Russo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Matrix stiffening promotes a tumor vasculature phenotype

(2016) Francois Bordeleau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type I collagen aging impairs discoidin domain receptor 2-mediated tumor cell growth suppression

(2016) Charles Saby et al.   Oncotarget

Role of receptor for advanced glycation end products in the complication and progression of various types of cancers

(2015) Parth Malik et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Human breast cancer invasion and aggression correlates with ECM stiffening and immune cell infiltration

(2015) I. Acerbi et al.   Integrative Biology

Advanced Glycation End Products (AGE) Potently Induce Autophagy through Activation of RAF Protein Kinase and Nuclear Factor κB (NF-κB)

(2015) Neeharika Verma et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Oncogenic MicroRNAs: Key Players in Malignant Transformation

(2015) Tania Frixa et al.   Cancers

Instructive Roles of Extracellular Matrix on Autophagy

(2014) Thomas Neill et al.   AMERICAN JOURNAL OF PATHOLOGY

3D Traction Stresses Activate Protease-Dependent Invasion of Cancer Cells

(2014) Aereas Aung et al.   BIOPHYSICAL JOURNAL

Does cancer risk increase with HbA1c, independent of diabetes?

(2014) J C de Beer et al.   BRITISH JOURNAL OF CANCER

Advanced glycation endproducts trigger autophagy in cadiomyocyte Via RAGE/PI3K/AKT/mTOR pathway

(2014) Xuwei Hou et al.   Cardiovascular Diabetology

Glycated Collagen Induces α11 Integrin Expression Through TGF-β2 and Smad3

(2014) Ilana Talior-Volodarsky et al.   JOURNAL OF CELLULAR PHYSIOLOGY

AGE-modified basement membrane cooperates with Endo180 to promote epithelial cell invasiveness and decrease prostate cancer survival

(2014) Mercedes Rodriguez-Teja et al.   JOURNAL OF PATHOLOGY

Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression

(2014) Janna K Mouw et al.   NATURE MEDICINE

RAGE, inflammation and oral cancer: Recreating the connexion

(2014) Samapika Routray   ORAL ONCOLOGY

The wound healing, chronic fibrosis, and cancer progression triad

(2014) Brad Rybinski et al.   PHYSIOLOGICAL GENOMICS

Cancer biology in diabetes

(2014) Shi Sen et al.   Journal of Diabetes Investigation

Hyperglycemia as a Risk Factor for Cancer Progression

(2014) Tae Young Ryu et al.   Diabetes & Metabolism Journal

Collective Invasion in Breast Cancer Requires a Conserved Basal Epithelial Program

(2013) Kevin J. Cheung et al.   CELL

A Mechanical Checkpoint Controls Multicellular Growth through YAP/TAZ Regulation by Actin-Processing Factors

(2013) Mariaceleste Aragona et al.   CELL

Signalling pathways linking integrins with cell cycle progression

(2013) Paulina Moreno-Layseca et al.   MATRIX BIOLOGY

Diabetes mellitus and cancer risk: Review of the epidemiological evidence

(2012) Kentaro Shikata et al.   CANCER SCIENCE

The receptor for advanced glycation end-products: A complex signaling scenario for a promiscuous receptor

(2012) Armando Rojas et al.   CELLULAR SIGNALLING

The extracellular matrix: A dynamic niche in cancer progression

(2012) Pengfei Lu et al.   JOURNAL OF CELL BIOLOGY

Cancer-Related Inflammation

(2012) Juliana Candido et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Matrix rigidity regulates a switch between TGF-β1–induced apoptosis and epithelial–mesenchymal transition

(2012) Jennifer L. Leight et al.   MOLECULAR BIOLOGY OF THE CELL

Rage signalling promotes intestinal tumourigenesis

(2012) J Heijmans et al.   ONCOGENE

The Role of Autophagy in Cancer: Therapeutic Implications

(2011) Z. J. Yang et al.   MOLECULAR CANCER THERAPEUTICS

Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells

(2011) D Kong et al.   ONCOGENE

Transforming growth factor-β and the hallmarks of cancer

(2010) Maozhen Tian et al.   CELLULAR SIGNALLING

Diabetes and Cancer: A consensus report

(2010) E. Giovannucci et al.   DIABETES CARE

The extracellular matrix at a glance

(2010) C. Frantz et al.   JOURNAL OF CELL SCIENCE

Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype

(2010) Robert W. Tilghman et al.   PLoS One

Autophagy and Metabolism

(2010) J. D. Rabinowitz et al.   SCIENCE

Hyperglycemia and Glycation in Diabetic Complications

(2009) Anne Negre-Salvayre et al.   ANTIOXIDANTS & REDOX SIGNALING

Epithelial-mesenchymal transition in cancer development and its clinical significance

(2009) Masaaki Iwatsuki et al.   CANCER SCIENCE

Fueling inflammation at tumor microenvironment: the role of multiligand/rage axis

(2009) A. Rojas et al.   CARCINOGENESIS

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

The receptor RAGE: Bridging inflammation and cancer

(2009) Astrid Riehl et al.   Cell Communication and Signaling

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

The extracellular matrix in development and morphogenesis: A dynamic view

(2009) Tania Rozario et al.   DEVELOPMENTAL BIOLOGY

Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

(2009) Jose Miguel López-Novoa et al.   EMBO Molecular Medicine

Impact of Diabetes Mellitus on Complications and Outcomes of Adjuvant Chemotherapy in Older Patients With Breast Cancer

(2009) Tomasz P. Srokowski et al.   JOURNAL OF CLINICAL ONCOLOGY

Collagen-based cell migration models in vitro and in vivo

(2009) Katarina Wolf et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Collagen density promotes mammary tumor initiation and progression

(2008) Paolo P Provenzano et al.   BMC Medicine

Long-term All-Cause Mortality in Cancer Patients With Preexisting Diabetes Mellitus

(2008) Bethany B. Barone   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Non-enzymatic glycation of type I collagen diminishes collagen-proteoglycan binding and weakens cell adhesion

(2008) Kristin L. Reigle et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The Integrin-coupled Signaling Adaptor p130Cas Suppresses Smad3 Function in Transforming Growth Factor-β Signaling

(2008) Wook Kim et al.   MOLECULAR BIOLOGY OF THE CELL

Cancer-related inflammation

(2008) Alberto Mantovani et al.   NATURE