Article
Polymer Science
Somayeh Sharafi Zamir, Babak Fathi, Abdellah Ajji, Mathieu Robert, Said Elkoun
Summary: The study shows that the addition of grafted starch nanocrystals has a significant impact on the oxygen and water vapor permeability of poly(lactic acid), leading to a reduction in permeability by approximately 70% and 50% respectively. This has the potential to develop PLA nanocomposites for use in food packaging applications.
Review
Materials Science, Composites
Ling Zhou, Kai Ke, Ming-Bo Yang, Wei Yang
Summary: This review summarizes recent research on the chemical modification strategies of cellulose in PLA/cellulose composites over the past five years, focusing on two major classifications: reactions of small molecules modified cellulose and reactions of polymers modified cellulose. The review discusses the relationship between the structure of grafted small molecules/polymers and the mechanical properties of PLA composites, and addresses common problems hindering the development of high-performance PLA/cellulose composites through chemical modification.
COMPOSITES COMMUNICATIONS
(2021)
Article
Materials Science, Composites
Zhongyuan Xie, Mingwei Guo, Zhangyun Chen, Hua Jiang
Summary: The nanocomposite films of poly(lactic acid) (PLA) and palmitoylated cellulose nanocrystals (e-CNCs) were studied. Raman spectra confirmed the formation of hydrogen bonding interactions between PLA and e-CNCs. Incorporating 1.0 wt% of e-CNCs resulted in smaller PLA spherulites, increased PLA crystallinity, and improved dispersibility within the PLA matrix. The nanocomposite exhibited some elasticity and showed enhanced mechanical properties.
POLYMER COMPOSITES
(2023)
Article
Polymer Science
Qianjin Zhu, Kaixin Chang, Liyan Qi, Xinyi Li, Woming Gao, Qinwei Gao
Summary: In this study, PLLA films were surface-modified using different solutions, leading to changes in their structure and properties. The modification with PDLA weakened the crystal structure of the films, while modification with PDLAG increased the stereocomplex (SC) structure and decreased the homogeneous crystal (HC) structure.
Review
Polymer Science
Sixiang Zhai, Qingying Liu, Yuelong Zhao, Hui Sun, Biao Yang, Yunxuan Weng
Summary: This paper summarizes the research progress of modifying polylactic acid with lignin and cellulose in recent years, focusing on the effects of lignin and cellulose on the mechanical properties of polylactic acid composite materials. It is expected that the development of polylactic acid composite materials will be improved in this regard.
Article
Chemistry, Applied
Qian Ren, Wanwan Li, Shijie Cui, Wenyu Ma, Xiuyu Zhu, Minghui Wu, Long Wang, Wenge Zheng, Takeshi Semba, Masahiro Ohshima
Summary: In this study, an innovative PLA/CNF nanocomposite foam with a bimodal cell structure was prepared using a simple one-step depressurization foaming process with supercritical carbon dioxide as the foaming agent. The cell structure of the foam was influenced by the crystallization rate and phase interface. The prepared foam exhibited high expansion ratio, low thermal conductivity, and excellent compression performance, making it suitable for applications in packaging and construction materials.
CARBOHYDRATE POLYMERS
(2023)
Article
Agricultural Engineering
Yuanyuan Yin, Xiuzhi Tian, Xue Jiang, Ping Zhu
Summary: By surface grafting poly(butyl acrylate) (PBA), customized functionalization of cellulose nanocrystals (CNCs) was achieved to improve their thermal stability and compatibility with poly(lactic acid) (PLA). The modified CNCs were uniformly dispersed throughout the PLA matrix, resulting in improved interactions between the CNCs and PLA. Tensile tests showed significant enhancements in tensile strength, elongation, and Young's Modulus with the addition of CNCs.
INDUSTRIAL CROPS AND PRODUCTS
(2022)
Article
Chemistry, Physical
Alessandro Ianiro, Jose Augusto Berrocal, Remco Tuinier, Michael Mayer, Christoph Weder
Summary: This paper presents a theoretical investigation on a new actuator design using anisotropic colloidal particles grafted with stimuli-responsive polymer chains. These artificial muscles combine the osmotic actuation principle of hydrogels with the structural alignment of colloidal liquid crystals for directional motion. The study identifies the solubility, degree of polymerization, salt concentration, and grafting density of the polymer chains as important factors for actuator performance and tunability. Computational results suggest that the proposed material matches or exceeds the performances of natural muscles, providing guidelines for the realization of artificial muscles with predefined actuation properties.
JOURNAL OF CHEMICAL PHYSICS
(2023)
Article
Materials Science, Paper & Wood
Oleg V. Surov, Marina I. Voronova, Anatoly G. Zakharov
Summary: In this study, methods for synthesizing cellulose nanocrystal (CNC) conjugates with chlorotriazine reactive dyes (RDs) were successfully developed. Characterization using various techniques confirmed the successful covalent bonding of the dyes to the CNC surface, with high colloidal stability observed in aqueous suspensions. Additionally, the CNC-RD conjugates effectively stabilized n-decane emulsions in water, demonstrating their potential in applications such as Pickering emulsions.
Article
Chemistry, Physical
Qian Ren, Minghui Wu, Long Wang, Wenge Zheng, Yuta Hikima, Takeshi Semba, Masahiro Ohshima
Summary: This study proposes a scalable and green foam injection molding technique to produce high-performance PLA foams by adding cellulose nanofibers. The added nanofibers significantly improve the properties of PLA and enhance the foaming ability, resulting in the successful production of PLA foam material with improved performance. This green strategy opens up new possibilities for developing fully-biobased, lightweight and high-performance PLA material.
JOURNAL OF SUPERCRITICAL FLUIDS
(2022)
Article
Materials Science, Paper & Wood
Kazim Kose, Miran Mavlan, Lokman Uzun, Jeffry P. Youngblood
Summary: A novel cyclodextrin-modified nanocomposite adsorbent was successfully synthesized for the removal of cholesterol and low-density lipoprotein. Experimental results demonstrated excellent adsorption performance, with agreement between experimental data and mathematical models.
Article
Food Science & Technology
Sonal S. Karkhanis, Nicole M. Stark, Ronald C. Sabo, Laurent M. Matuana
Summary: The study demonstrated that crackers packaged in PLA/CNC films had a longer shelf-life compared to those packaged in neat PLA films, especially performing better in high-humidity environments.
FOOD PACKAGING AND SHELF LIFE
(2021)
Article
Polymer Science
Somayeh Sharafi Zamir, Babak Fathi, Abdellah Ajji, Mathieu Robert, Said Elkoun
Summary: The effect of lactic acid grafted starch nanocrystals (g-SNCs) on the soil burial degradation rate of Poly (lactic acid) (PLA) was studied. The results showed that the addition of g-SNCs nanoparticles accelerated the degradation rate of PLA. Furthermore, the chemical bonds and material structure of PLA/g-SNCs changed after soil burial.
POLYMER DEGRADATION AND STABILITY
(2022)
Article
Materials Science, Multidisciplinary
Allen C. Chang, M. Bachir Messikh, Maximilian Kaiser, Kenneth R. Carter
Summary: Cellulose nanocrystals were functionalized with semiconducting polyfluorene grafts to create a composite material used as the emissive layer in OLED devices. The grafted polymer material exhibited high polymer loading and a network-like structure, showing blue emission characteristics similar to standard polyfluorene emitters. Excitonic and excimeric emission peaks were found at similar wavelengths in both the composite material OLED and the standard polyfluorene OLED, although differences in emissive intensity were observed.
ACS APPLIED POLYMER MATERIALS
(2021)
Article
Engineering, Multidisciplinary
Yi Zhang, Hao Du, Zhiyuan Qiu, Wentao Liu, Yubo Hu, Chao Wang, Jie Ding
Summary: The utilization of Poly-L-lactic acid (PLLA) as a biodegradable material for biovascular scaffolds (BVS) has been hindered by its lack of active surface functional groups and high hydrophobicity, which impede endothelial cells' attachment and growth. To solve this problem, a polydopamine (PDA) coating technique, commonly used for metal stents, has been adapted. This method promotes EC adhesion and proliferation on PLLA surfaces, while inhibiting macrophage activation and the release of inflammatory factors. The reactive functional groups on the PDA-coated surface also provide a platform for immobilizing therapeutic molecules onto PLLA, enhancing the biocompatibility of PLLA cardiovascular stents.
ALEXANDRIA ENGINEERING JOURNAL
(2023)
Article
Chemistry, Physical
Jinli Qin, Zhaolu Wang, Jie Hu, Yuan Yuan, Ping Liu, Li Cheng, Zhengqing Kong, Ke Liu, Shouke Yan, Jianming Zhang
Summary: The study investigates the impact of ionic liquids (IL) on the liquid crystal self-assembly behavior of cellulose nanocrystals (CNCs). Results demonstrate that CNCs modified with positively charged IL (CNC-IL) can form chiral nematic structures at lower concentrations, showing distinct assembly behavior compared to original CNCs.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Materials Science, Composites
Xiao Wu, Yunxiao Liu, Haipeng Wu, Yongxin Duan, Jianming Zhang
Summary: This study successfully achieved the homogeneous dispersion of CNCs in PLLA by using PVAc modified CNCs, which improved the material's melt processibility and adhesion properties, resulting in significantly enhanced mechanical performance and dimensional stability.
COMPOSITES SCIENCE AND TECHNOLOGY
(2022)
Article
Materials Science, Composites
Jin Yin, Jian Hu, Yanchun Han, Yuwei Chen, Jiawei Hu, Zejun Zhang, Shasha Huang, Yongxin Duan, Hao Wu, Jianming Zhang
Summary: Reversible Plasticity Shape Memory (RPSM) polymers based on crosslinked natural rubber (NR) composites were fabricated in this study. The results showed that with the increase of nanofiller content, the elastomer deformation turned to plasticity deformation. The plasticity deformation of composites with high nanofiller loading could be rapidly recovered in hot water. Moreover, the stretch-induced crystals persisted in the stretched high-content composites even when the stress was unloaded.
COMPOSITES SCIENCE AND TECHNOLOGY
(2022)
Article
Materials Science, Composites
Ning Zhang, Yong Pang, Zhaohui Li, Chuanhui Yang, Lu Zong, Hongsheng Yang, Hao Wu, Yongxin Duan, Jianming Zhang
Summary: In this study, biodegradable PVA-based elastomers with excellent solvent barrier property and high elasticity were fabricated. The water-soluble resin PAE was used as a crosslinker to effectively crosslink carboxyl PVA chains. The collaborative triple networks in the prepared PVA composites contribute to their excellent elastomer behavior. Furthermore, these materials demonstrated highly efficient barrier performance against chemical solvents permeation as chemical protective gloves, and showed a high degradation rate.
COMPOSITES SCIENCE AND TECHNOLOGY
(2023)
Article
Chemistry, Physical
Selvaraj Nagarajan, Kuan-Ying Huang, Wei-Tsung Chuang, Jhih-Min Lin, Eamor M. Woo
Summary: Poly(p-dioxanone) (PPDO) is a bioabsorbable material commonly used in biomedical applications, with its crystal morphology dependent on temperature and polymorphism. PPDO can form ringless spherulites (RLS) and ring-banded spherulites (RBS) depending on the temperature, each with different crystal structures. The interior structure of PPDO-RBS consists of horizontal and vertical lamellae, and the growth patterns of ring bands can be customized.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Polymer Science
Hsiao-Hua Li, Selvaraj Nagarajan, Wei-Tsung Chuang, Yi-Wei Tsai, Eamor M. Woo
Summary: A unique composite dendritic spherulite is detected in a specific temperature range, and its assembly and morphology are studied using microscopy techniques and microbeam analysis. The branches in the spherulite originate from a common nucleus with different growth rates. This study provides insights into the mechanisms of crystal plate orientations and transformations.
Article
Chemistry, Physical
Selvaraj Nagarajan, Tzu-Ching Chuang, Wei-Tsung Chuang, Jhih-Min Lin, Eamor M. Woo
Summary: In an unprecedented manner, the formation mechanism of lamellar structure in ring-banded spherulites (RBSs) has been revealed using advanced synchrotron microbeam X-ray diffraction. The presence of periodically banded structure is confirmed through microscopy dissection morphology, and its sequential arrangement and orientation are demonstrated through real-time micrograph comparison. This methodology can be applied to a wide variety of polymers to analyze spherulites displaying periodic self-assembled patterns.
JOURNAL OF PHYSICAL CHEMISTRY C
(2023)
Article
Chemistry, Multidisciplinary
Cheng-En Yang, Selvaraj Nagarajan, Widyantari Rahmayanti, Chean-Cheng Su, Eamor M. Woo
Summary: This study used different model arylate polymers to investigate their crystallization behavior, and found that they all formed periodically banded spherulites with similar characteristics. By dissecting these structures in 3D, the universal mechanisms of crystal-by-crystal self-assembly from the nano- to microscale were revealed, resulting in the formation of final periodic aggregates. Fracture analysis showed that the birefringent-banded poly(decamethylene terephthalate) (PDT) spherulites contained multi-shell spheroid bands composed of perpendicularly intersecting lamellae bundles.
Article
Biochemistry & Molecular Biology
Widyantari Rahmayanti, Selvaraj Nagarajan, Ya-Sen Sun, Eamor M. Woo
Summary: This study found that five different aryl polyesters can form ring-banded spherulites with universal characteristics during crystallization. The research explored the correlations between micro/nanocrystal assemblies, grating architectures, and structural iridescent properties. The interior lamellar assembly of arylate polyesters' banded spherulites exhibits periodic birefringence patterns similar to those found in biological structures, resulting in iridescent color.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Chemistry, Multidisciplinary
Min-Han Hao, Selvaraj Nagarajan, Eamor M. Woo
Summary: This study used scanning electron microscopy and synchrotron radiation to analyze the crystal aggregates formed by poly(p-dioxanone) and poly(vinyl alcohol) during crystallization. The results showed that the periodic architectures were formed by alternating flat crystals and fibrils, with an oblique angle between the branches and the flat crystals.
Article
Chemistry, Multidisciplinary
Yunxiao Liu, Hongze Xu, Lijuan Zhou, Jianming Zhang
Summary: By adding a small amount of sodium citrate to an aqueous medium, a highly efficient grafting of bio-derived polyvinyl acetate (PVAc) onto the surface of cellulose nanocrystals (CNCs) was achieved through classical free radical polymerization initiated by cerium ammonium nitrate (CAN). With the increase of SC concentration from 0 to 0.45 mmol L-1, the grafting yields of PVAc on the CNC surface increased from 29.2% to 241.9%. The resulting CNC-PVAc can be fully degraded by soil burial for about 180 days and can be used as a new biodegradable nanofiller or polymer nanocomposite. Moreover, this strategy is applicable to various monomers and different surface groups of CNCs.
Article
Chemistry, Physical
Jinghua Wu, Jin Yin, Jian Hu, Qiran Wang, Hao Zhang, Rui Xin, Shaojuan Wang, Shouke Yan, Jianming Zhang
Summary: Natural rubber (NR) composites with bio-based chitin nanofibers (ChNFs) demonstrate a wide range of mechanical properties, transitioning from rubber to plastic behavior with increasing chitin levels. Mixing NR latex and a modified zwitterionic rigid chitin counterpart can create a constrained 3-dimensional network. When highly anisotropic ChNFs (30 wt%) are incorporated, strain-induced NR crystallization occurs at a lower strain and 3-dimensionally oriented crystallite formations resembling 3D-single crystals are observed for ChNFs content over 5 wt%. This study investigates the structure and morphology of the NR/ChNFs30 composite after strain-induced crystallization, paving the way for the development of novel multifunctional NR/ChNFs composites with shape memory abilities.
Article
Chemistry, Multidisciplinary
Guohui Yang, Xiaofang Zhang, Ruijia Wang, Xu Liu, Jianming Zhang, Lu Zong, Hongsheng Yang
Summary: An ultra-stretchable and elastic graphene aerogel was achieved by constructing a highly crimped and crosslinked graphene network using a microbubble-filled precursor. This conductive aerogel exhibited rubber-like elasticity with near zero Poisson's ratio, as well as temperature-invariant properties from -196.5 degrees C to 300 degrees C. It can function as a highly stretchable but strain-insensitive conductor under extreme environments, which is not possible with polymer-based materials. This work also provides new ideas for constructing inorganic ultra-stretchable materials.
MATERIALS HORIZONS
(2023)
Article
Chemistry, Multidisciplinary
Xiaofang Zhang, Lu Zong, Mingjie Li, Jianming Zhang, Chaoxu Li
Summary: This study demonstrates that graphene patterning can be triggered using a thermal needle and controlled by pre-infiltrating certain materials. Under specific conditions, cascade reduction reaction can be initiated by a low-temperature thermal needle and propagate at high speed. The thermal reduction mechanism also provides insights for high-precision laser writing on graphene substrates.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Multidisciplinary
Yunxiao Liu, Hongxiu Wei, Ziwei Liu, Xinran Liu, Yijie Fang, Min Jiang, Mingjie Li, Lijuan Zhou, Jianming Zhang
Summary: Cellulose nanocrystals (CNCs) have great potential in various industrial applications, but their green synthesis in an energy-efficient way remains challenging. In this study, a green, energy-saving, and high-efficiency method for extracting CNCs is proposed using NaOH granule-activated ammonium persulfate (APS) oxidation. By utilizing the synergistic effects of APS, NaOH, and cellulose raw materials, the decomposition of APS is promoted, resulting in the release of the crystalline part of cellulose sources. The addition of NaOH solid granules enables efficient utilization of the dissolution heat, reducing energy consumption in the CNC isolation process.
Review
Chemistry, Applied
Xingran Kou, Dongdong Su, Fei Pan, Xiwei Xu, Qingran Meng, Qinfei Ke
Summary: This review provides a systematic discussion of the application of molecular dynamics (MD) simulations in aroma compounds (ACs)/cyclodextrins (CDs) inclusion complexes (ICs). It covers the establishment of the simulation process, parameter selection, model evaluation, and various application cases, summarizing the major achievements and challenges of this method.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Haoyu Yu, Quanbin Zhang, Ammad Ahmad Farooqi, Jing Wang, Yang Yue, Lihua Geng, Ning Wu
Summary: Brown algae are rich in fucoidan, which has been found to have anti-cancer and anti-metastasis effects. Fucoidan inhibits tumor cell growth, proliferation, and metastasis, and also promotes immune responses in the tumor microenvironment.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Liang Dong, Yanan Li, Hailin Cong, Bing Yu, Youqing Shen
Summary: Gene therapy is a revolutionary treatment that requires suitable vectors for protecting and releasing exogenous nucleic acids in target cells. Chitosan, as a non-viral vector, has gained attention due to its good biocompatibility and ability to load large amounts of nucleic acids. This paper summarizes the potential of chitosan and its derivatives as gene delivery vector materials, discusses factors influencing transfection efficiency, performance evaluation, ways to optimize infectious efficiency, and current research development directions. It also provides an outlook on the future prospects of chitosan.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ana Iglesias-Mejuto, Beatriz Magarinos, Tania Ferreira-Goncalves, Ricardo Starbird-Perez, Carmen Alvarez-Lorenzo, Catarina Pinto Reis, Ines Ardao, Carlos A. Garcia-Gonzalez
Summary: This study developed a novel processing strategy to manufacture drug-loaded and personalized aerogels with nanostructures. The aerogels demonstrated bioactivity and antimicrobial effects, promoting bone regeneration and preventing infections in bone tissue engineering.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Zhenxu Shi, Dimei Yang, Yan Zhou, Xinyu Chen, Lin Gan, Jin Huang
Summary: This study proposes a micro-assembly method to improve the photoluminescent properties of crystalline cellulose nanocrystals (CNCs) by organizing them within a sub-micrometer-sized metal-organic framework and coating with TiO2. The TiO2 coating prevents CNC assembly breakdown and allows information to be revealed using screenprinted labels for anti-counterfeiting purposes.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Xuejiao Liu, Bin Fu, Jierong Chen, Zhenyu Sun, Dongdong Zheng, Zhonghua Li, Bing Gu, Ying Zhang, Haojie Lu
Summary: Liver disease is a major cause of global mortality, and identifying biomarkers for diagnosing its progression is crucial for improving outcomes. Targeted mass spectrometry is a powerful tool for verifying biomarker candidates and clinical applications, particularly for glycoproteins translation. However, the limitation of analyzing only one sample per run has become apparent. In this study, a high-throughput intact N-glycopeptides quantification strategy was developed, allowing the validation of 20 samples per run with an average analysis time of 3 minutes per sample. The strategy was applied in a cohort of 461 serum samples and identified a panel of 10 IgG N-glycopeptides that have strong clinical utility in evaluating the severity of liver disease.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Qian Wang, Hao Jiang, Hongli Zhang, Weiqiao Lu, Xiao Wang, Wenfeng Xu, Jia Li, Youjing Lv, Guoyun Li, Chao Cai, Guangli Yu
Summary: This study proposes a novel strategy of antibody-beta-glucan conjugates (AGC) to enhance the antitumor immune response to immune checkpoint blockade (ICB) therapy. AGC demonstrated powerful tumor suppression and promoted interaction between tumor cells and dendritic cells (DCs), thereby enhancing immunotherapeutic benefits.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Chaeyeon Lee, Sojeong Lee, Sang Wook Kang
Summary: The study aims to enhance the properties of porous membranes by addressing the limitations associated with phase separation. By using cellulose acetate and citric acid, the researchers were able to fabricate membranes with improved mechanical strength and thermal stability. The cross-linking effect of citric acid resulted in a more uniform pore structure and higher porosity.
CARBOHYDRATE POLYMERS
(2024)
Review
Chemistry, Applied
Tejaswini Kolipaka, Giriraj Pandey, Noella Abraham, Dadi A. Srinivasarao, Rajeev Singh Raghuvanshi, P. S. Rajinikanth, Vidya Tickoo, Saurabh Srivastava
Summary: This review focuses on the design and application of polysaccharide-based hydrogel wound dressings, highlighting aspects such as biocompatibility, biodegradability, drug entrapment, moisturizing ability, swelling, and mechanical properties. Additionally, various crosslinking methods and recent developments in stimuli-responsive hydrogels are discussed.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Anqi Xu, Nan Zhang, Shixing Su, Hongyu Shi, Daoqiang Lu, Xifeng Li, Xin Zhang, Xin Feng, Zhuohua Wen, Gengwu Ma, Mengshi Huang, Chi Huang, Yuqi Hu, Hao Yuan, Qinwen Liu, Daogang Guan, Jun Wang, Chuanzhi Duan
Summary: The study presents a one-pot radical polymerization method to fabricate a hydrogel with adhesive properties, which can effectively treat bacterial-infected diabetic wounds and accelerate wound healing.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Montarop Yamabhai, Munthipha Khamphio, Thae Thae Min, Chai Noy Soem, Nguyen Cao Cuong, Waheni Rizki Aprilia, Krisanai Luesukprasert, Karsidete Teeranitayatarn, Atthaphon Maneedaeng, Tina R. Tuveng, Silje B. Lorentzen, Simen Antonsen, Paiboon Jitprasertwong, Vincent G. H. Eijsink
Summary: The study investigates the bioconversion of chitosan into soluble anti-inflammatory chitosan oligosaccharides (CHOS) using an enzyme. The results show that the generated CHOS have anti-inflammatory activity, but the magnitude of the activity depends on the substrate and production process. Different methods of dissolving chitosan also affect the properties of CHOS. The study highlights the importance of quality assurance in CHOS preparations.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Wen Cao, Jiangping Wu, Xinya Zhao, Zixu Li, Jie Yu, Taili Shao, Xuefeng Hou, Lutan Zhou, Chunfei Wang, Guodong Wang, Jun Han
Summary: In this study, a water-soluble polysaccharide (PLP1) was successfully isolated and purified from Pueraria lobata. It was found that PLP1 was composed of specific glycosidic units and exhibited a better free radical-scavenging ability. Moreover, PLP1 effectively protected the liver against acute alcoholic liver disease (ALD) in mice.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ya Su, Yaqian Liu, Xueyan Hu, Yueqi Lu, Jinyuan Zhang, Wenbo Jin, Wang Liu, Yan Shu, Yuen Yee Cheng, Wenfang Li, Yi Nie, Bo Pan, Kedong Song
Summary: A 3D printed scaffold based on carbon dots-curcumin nano-drug release has been developed for drug delivery after breast cancer surgery. The scaffold showed effective inhibition of tumor growth, antibacterial activity, and promotion of wound healing, making it a promising approach for preventing tumor recurrence.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Ekaterina Sokolova, Diane Jouanneau, Antonin Chevenier, Murielle Jam, Nathalie Desban, Pierre Colas, Elizabeth Ficko-Blean, Gurvan Michel
Summary: Carrageenans, a compound synthesized in red algae, have various biological properties and are valuable in the pharmaceutical and cosmetic industries. Their fine structure affects wound healing, oxidative processes, hemostasis, and inflammation. Enzymatic modification of carrageenans produces oligosaccharides that bind to natural human serum antibodies and specific antibodies, showing potential for therapeutic applications.
CARBOHYDRATE POLYMERS
(2024)
Article
Chemistry, Applied
Yan Shi, Miao Yu, Kaijin Qiu, Tiantian Kong, Chunjing Guo, Wenxue Zhang, Daquan Chen, Ming Kong
Summary: In this study, functionalized transfersomes were developed to co-deliver doxorubicin and 1MT towards primary tumors and tumor draining lymph nodes via transdermal administration using microneedles. The results showed that the nano-complexed microneedles exhibited a stronger suppression in tumor growth compared to the intravenous group.
CARBOHYDRATE POLYMERS
(2024)
