EWS-FLI1 regulates a transcriptional program in cooperation with Foxq1 in mouse Ewing sarcoma

Tribbles in the 21st Century: The Evolving Roles of Tribbles Pseudokinases in Biology and Disease

(2017) Patrick A. Eyers et al.   TRENDS IN CELL BIOLOGY

C/EBPβ-1 promotes transformation and chemoresistance in Ewing sarcoma cells

(2017) Jamie D. Gardiner et al.   Oncotarget

Modeling Alveolar Soft Part Sarcoma Unveils Novel Mechanisms of Metastasis

(2016) Miwa Tanaka et al.   CANCER RESEARCH

Fox transcription factors: from development to disease

(2016) Maria L. Golson et al.   DEVELOPMENT

MEIS1-mediated transactivation of synaptotagmin-like 1 promotes CXCL12/CXCR4 signaling and leukemogenesis

(2016) Takashi Yokoyama et al.   JOURNAL OF CLINICAL INVESTIGATION

Combined experience of six independent laboratories attempting to create an Ewing sarcoma mouse model

(2016) Tsion Zewdu Minas et al.   Oncotarget

An EWS-FLI1 -Induced Osteosarcoma Model Unveiled a Crucial Role of Impaired Osteogenic Differentiation on Osteosarcoma Development

(2016) Shingo Komura et al.   Stem Cell Reports

Paracrine Effect of NRG1 and HGF Drives Resistance to MEK Inhibitors in Metastatic Uveal Melanoma

(2015) H. Cheng et al.   CANCER RESEARCH

CTCF-Mediated Human 3D Genome Architecture Reveals Chromatin Topology for Transcription

(2015) Zhonghui Tang et al.   CELL

Ewing Sarcoma: Current Management and Future Approaches Through Collaboration

(2015) Nathalie Gaspar et al.   JOURNAL OF CLINICAL ONCOLOGY

Chimeric EWSR1-FLI1 regulates the Ewing sarcoma susceptibility gene EGR2 via a GGAA microsatellite

(2015) Thomas G P Grünewald et al.   NATURE GENETICS

Combining lapatinib and pertuzumab to overcome lapatinib resistance due to NRG1-mediated signalling in HER2-amplified breast cancer

(2015) Wing-yin Leung et al.   Oncotarget

Epigenome Mapping Reveals Distinct Modes of Gene Regulation and Widespread Enhancer Reprogramming by the Oncogenic Fusion Protein EWS-FLI1

(2015) Eleni M. Tomazou et al.   Cell Reports

EWS/FLI1 Target Genes and Therapeutic Opportunities in Ewing Sarcoma

(2015) Florencia Cidre-Aranaz et al.   Frontiers in Oncology

Involvement of FoxQ1 in NSCLC through regulating EMT and increasing chemosensitivity

(2015) Jian Feng et al.   Oncotarget

Somatic chromosomal translocation between Ewsr1 and Fli1 loci leads to dilated cardiomyopathy in a mouse model

(2015) Miwa Tanaka et al.   Scientific Reports

EWS-FLI1 Utilizes Divergent Chromatin Remodeling Mechanisms to Directly Activate or Repress Enhancer Elements in Ewing Sarcoma

(2014) Nicolò Riggi et al.   CANCER CELL

PDGFR  and   Play Critical Roles in Mediating Foxq1-Driven Breast Cancer Stemness and Chemoresistance

(2014) F. Meng et al.   CANCER RESEARCH

Ewing’s sarcoma precursors are highly enriched in embryonic osteochondrogenic progenitors

(2014) Miwa Tanaka et al.   JOURNAL OF CLINICAL INVESTIGATION

Overexpression of NRG1 promotes progression of gastric cancer by regulating the self-renewal of cancer stem cells

(2014) Myoung-Eun Han et al.   JOURNAL OF GASTROENTEROLOGY

Neuregulin 1-activated ERBB4 interacts with YAP to induce Hippo pathway target genes and promote cell migration

(2014) J. W. Haskins et al.   Science Signaling

Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes

(2014) Saravana M. Dhanasekaran et al.   Nature Communications

The Genomic Landscape of Pediatric Ewing Sarcoma

(2014) B. D. Crompton et al.   Cancer Discovery

Genomic Landscape of Ewing Sarcoma Defines an Aggressive Subtype with Co-Association of STAG2 and TP53 Mutations

(2014) F. Tirode et al.   Cancer Discovery

The Genomic Landscape of the Ewing Sarcoma Family of Tumors Reveals Recurrent STAG2 Mutation

(2014) Andrew S. Brohl et al.   PLoS Genetics

COP1 targets C/EBP  for degradation and induces acute myeloid leukemia via Trib1

(2013) A. Yoshida et al.   BLOOD

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

(2013) Jakob Lovén et al.   CELL

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

Identification of TRIB1 R107L gain-of-function mutation in human acute megakaryocytic leukemia

(2012) T. Yokoyama et al.   BLOOD

Neuregulin in Cardiovascular Development and Disease

(2012) Oghenerukevwe Odiete et al.   CIRCULATION RESEARCH

Epithelial cell adhesion molecules and epithelial mesenchymal transition (EMT) markers in Ewing's sarcoma family of tumors (ESFTs). Do they offer any prognostic significance?

(2012) Isidro Machado et al.   VIRCHOWS ARCHIV

Tribbles in disease: Signaling pathways important for cellular function and neoplastic transformation

(2011) Takashi Yokoyama et al.   CANCER SCIENCE

Trib1 links the MEK1/ERK pathway in myeloid leukemogenesis

(2010) T. Yokoyama et al.   BLOOD

FOXQ1 Is Overexpressed in Colorectal Cancer and Enhances Tumorigenicity and Tumor Growth

(2010) H. Kaneda et al.   CANCER RESEARCH

Nrg1/ErbB signaling networks in Schwann cell development and myelination

(2010) Jason Newbern et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Ewing sarcoma demonstrates racial disparities in incidence-related and sex-related differences in outcome

(2009) Muhammad U. Jawad et al.   CANCER

Advances in Ewing's Sarcoma Research: Where Are We Now and What Lies Ahead?

(2009) J. L. Ordonez et al.   CANCER RESEARCH

The Oncogenic EWS-FLI1 Protein Binds In Vivo GGAA Microsatellite Sequences with Potential Transcriptional Activation Function

(2009) Noëlle Guillon et al.   PLoS One

EWS-FLI-1 Expression Triggers a Ewing's Sarcoma Initiation Program in Primary Human Mesenchymal Stem Cells

(2008) N. Riggi et al.   CANCER RESEARCH

Microsatellites as EWS/FLI response elements in Ewing's sarcoma

(2008) K. Gangwal et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA