Tamoxifen Never Ceases to Amaze: New Findings on Non-Estrogen Receptor Molecular Targets and Mediated Effects

Tamoxifen Suppresses the Growth of Malignant Pleural Mesothelioma Cells

(2016) CORMAC J JENNINGS et al.   ANTICANCER RESEARCH

Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia

(2016) Samy A. F. Morad et al.   JOURNAL OF LIPID RESEARCH

Tamoxifen Induces Apoptosis of Leishmania major Promastigotes in Vitro

(2016) Masoud Doroodgar et al.   KOREAN JOURNAL OF PARASITOLOGY

Prognostic role of sex steroid receptors in pancreatic adenocarcinoma

(2016) Despoina Georgiadou et al.   PATHOLOGY RESEARCH AND PRACTICE

Tamoxifen in combination with temozolomide induce a synergistic inhibition of PKC-pan in GBM cell lines

(2015) Joana Balça-Silva et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Tamoxifen regulation of sphingolipid metabolism—Therapeutic implications

(2015) Samy A.F. Morad et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Inhibition of angiogenesis by selective estrogen receptor modulators through blockade of cholesterol trafficking rather than estrogen receptor antagonism

(2015) Joong Sup Shim et al.   CANCER LETTERS

Anti-Mycobacterial Activity of Tamoxifen Against Drug-Resistant and Intra-Macrophage Mycobacterium tuberculosis

(2015) Woong Sik Jang et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

A phase II trial of tamoxifen and bortezomib in patients with recurrent malignant gliomas

(2015) Yazmín Odia et al.   JOURNAL OF NEURO-ONCOLOGY

Tamoxifen as a new therapeutic tool for neutrophilic lung inflammation

(2015) Barbara Perez et al.   RESPIROLOGY

Radiosensitization of human glioma cells by tamoxifen is associated with the inhibition of PKC-ι activity in vitro

(2015) LEI YANG et al.   Oncology Letters

In VitroandIn VivoEffects of Tamoxifen against Larval Stage Echinococcus granulosus

(2014) María Celeste Nicolao et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Tamoxifen as the first targeted long-term adjuvant therapy for breast cancer

(2014) V Craig Jordan   ENDOCRINE-RELATED CANCER

Beneficial role of tamoxifen in experimentally induced cardiac hypertrophy

(2014) Bhoomika M. Patel et al.   Pharmacological Reports

Tamoxifen use for the management of mania: a review of current preclinical evidence

(2014) Fernanda Armani et al.   PSYCHOPHARMACOLOGY

Mitochondria: The gateway for tamoxifen-induced liver injury

(2014) Mariana P.C. Ribeiro et al.   TOXICOLOGY

Estrogen Receptor Antagonists Are Anti-Cryptococcal Agents That Directly Bind EF Hand Proteins and Synergize with Fluconazole In Vivo

(2014) A. Butts et al.   mBio

Tamoxifen enhances the anticancer effect of cantharidin and norcantharidin in pancreatic cancer cell lines through inhibition of the protein kinase C signaling pathway

(2014) XIN XIE et al.   Oncology Letters

CB1 and CB2 receptors are novel molecular targets for Tamoxifen and 4OH-Tamoxifen

(2013) Paul L. Prather et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Tamoxifen magnifies therapeutic impact of ceramide in human colorectal cancer cells independent of p53

(2013) Samy A.F. Morad et al.   BIOCHEMICAL PHARMACOLOGY

Tamoxifen reduces P-gp-mediated multidrug resistance via inhibiting the PI3K/Akt signaling pathway in ER-negative human gastric cancer cells

(2013) Zonglei Mao et al.   BIOMEDICINE & PHARMACOTHERAPY

4-Hydroxytamoxifen Induces Autophagic Death through K-Ras Degradation

(2013) L. Kohli et al.   CANCER RESEARCH

The combination of the antiestrogen endoxifen with all-trans-retinoic acid has anti-proliferative and anti-migration effects on melanoma cells without inducing significant toxicity in non-neoplasic cells

(2013) Mariana P.C. Ribeiro et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Apoptotic effects of tamoxifen on leukocytes from horse peripheral blood and bronchoalveolar lavage fluid

(2013) J. Sarmiento et al.   VETERINARY RESEARCH COMMUNICATIONS

Protein Kinase C and Oxidative Stress in an Animal Model of Mania

(2012) Amanda Valnier Steckert et al.   CURRENT NEUROVASCULAR RESEARCH

Tamoxifen inhibits migration of estrogen receptor-negative hepatocellular carcinoma cells by blocking the swelling-activated chloride current

(2012) Jianwen Mao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Tamoxifen induces apoptosis of mouse microglia cell line BV-2 cells via both mitochondrial and death receptor pathways

(2012) Zhengwei Li et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Selective estrogen receptor modulators inhibit hepatitis C virus infection at multiple steps of the virus life cycle

(2012) Yuko Murakami et al.   MICROBES AND INFECTION

Role of PKC-ERK signaling in tamoxifen-induced apoptosis and tamoxifen resistance in human breast cancer cells

(2012) Fukang Xie   ONCOLOGY REPORTS

Tamoxifen enhances therapeutic effects of gemcitabine on cholangiocarcinoma tumorigenesis

(2011) Gu Jing et al.   LABORATORY INVESTIGATION

Progress in endocrine approaches to the treatment and prevention of breast cancer

(2011) Ifeyinwa Obiorah et al.   MATURITAS

Tamoxifen depresses glutamate release through inhibition of voltage-dependent Ca2+ entry and protein kinase Cα in rat cerebral cortex nerve terminals

(2011) Jinn-Rung Kuo et al.   NEUROCHEMISTRY INTERNATIONAL

Zinc(II) ion mediates tamoxifen-induced autophagy and cell death in MCF-7 breast cancer cell line

(2010) Jung Jin Hwang et al.   BIOMETALS

Potent inhibition of rhabdoid tumor cells by combination of flavopiridol and 4OH-tamoxifen

(2010) Velasco Cimica et al.   BMC CANCER

Tamoxifen and raloxifene suppress the proliferation of estrogen receptor-negative cells through inhibition of glutamine uptake

(2010) Valentina K. Todorova et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Voltage-dependent anion channel as a resident protein of lipid rafts: post-transductional regulation by estrogens and involvement in neuronal preservation against Alzheimer’s disease

(2010) Jose Luis Herrera et al.   JOURNAL OF NEUROCHEMISTRY

Molecular Mechanisms of Tamoxifen Therapy for Cholangiocarcinoma: Role of Calmodulin

(2009) P. Pawar et al.   CLINICAL CANCER RESEARCH

Tamoxifen as a potential antileishmanial agent: efficacy in the treatment of Leishmania braziliensis and Leishmania chagasi infections

(2008) D. C. Miguel et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Tamoxifen: Catalyst for the change to targeted therapy

(2007) V. Craig Jordan   EUROPEAN JOURNAL OF CANCER