Optimal Therapy Scheduling Based on a Pair of Collaterally Sensitive Drugs

Tumor Evolution as a Therapeutic Target

(2017) Nabil Amirouchene-Angelozzi et al.   Cancer Discovery

Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution

(2017) Vanessa D. Jonsson et al.   Scientific Reports

Collateral sensitivity networks reveal evolutionary instability and novel treatment strategies in ALK mutated non-small cell lung cancer

(2017) Andrew Dhawan et al.   Scientific Reports

The Cancer Stem Cell Fraction in Hierarchically Organized Tumors Can Be Estimated Using Mathematical Modeling and Patient-Specific Treatment Trajectories

(2016) Benjamin Werner et al.   CANCER RESEARCH

Exploiting Temporal Collateral Sensitivity in Tumor Clonal Evolution

(2016) Boyang Zhao et al.   CELL

Spatial Metrics of Tumour Vascular Organisation Predict Radiation Efficacy in a Computational Model

(2016) Jacob G. Scott et al.   PLoS Computational Biology

Steering Evolution with Sequential Therapy to Prevent the Emergence of Bacterial Antibiotic Resistance

(2015) Daniel Nichol et al.   PLoS Computational Biology

Parameterizing the Logistic Model of Tumor Growth by DW-MRI and DCE-MRI Data to Predict Treatment Response and Changes in Breast Cancer Cellularity during Neoadjuvant Chemotherapy

(2014) Nkiruka C Atuegwu et al.   Translational Oncology

The Model Muddle: In Search of Tumor Growth Laws

(2013) P. Gerlee   CANCER RESEARCH

Optimal policies of non-cross-resistant chemotherapy on Goldie and Coldman’s cancer model

(2013) Jeng-Huei Chen et al.   MATHEMATICAL BIOSCIENCES

Use of Collateral Sensitivity Networks to Design Drug Cycling Protocols That Avoid Resistance Development

(2013) L. Imamovic et al.   Science Translational Medicine

Non-Darwinian dynamics in therapy-induced cancer drug resistance

(2013) Angela Oliveira Pisco et al.   Nature Communications

Quantifying the Role of Angiogenesis in Malignant Progression of Gliomas: In Silico Modeling Integrates Imaging and Histology

(2011) K. R. Swanson et al.   CANCER RESEARCH

Phenotypic plasticity and epithelial-mesenchymal transitions in cancer and normal stem cells?

(2011) Christina Scheel et al.   INTERNATIONAL JOURNAL OF CANCER

The influence of toxicity constraints in models of chemotherapeutic protocol escalation

(2011) E. A. J. Boston et al.   MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA

The Worst Drug Rule Revisited: Mathematical Modeling of Cyclic Cancer Treatments

(2010) Allen A. Katouli et al.   BULLETIN OF MATHEMATICAL BIOLOGY