Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution
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Title
Novel computational method for predicting polytherapy switching strategies to overcome tumor heterogeneity and evolution
Authors
Keywords
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Journal
Scientific Reports
Volume 7, Issue 1, Pages -
Publisher
Springer Nature
Online
2017-03-13
DOI
10.1038/srep44206
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- (2013) Kristian Cibulskis et al. NATURE BIOTECHNOLOGY
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- Evolutionary dynamics of cancer in response to targeted combination therapy
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- (2012) Zhenfeng Zhang et al. NATURE GENETICS
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- (2008) S. Chareyron et al. JOURNAL OF THEORETICAL BIOLOGY
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