Impaired Langerhans cell migration in psoriasis is due to an altered keratinocyte phenotype induced by interleukin-17

Interleukin-17 and interleukin-23 regulate Langerhans cell migration

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IκBζ: A key protein in the pathogenesis of psoriasis

(2016) Claus Johansen   CYTOKINE

Increased expression of interleukin-17 pathway genes in nonlesional skin of moderate-to-severe psoriasis vulgaris

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IκBζ is a key driver in the development of psoriasis

(2015) Claus Johansen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cellular sources of IL-17 in psoriasis: a paradigm shift?

(2014) Romy R. M. C. Keijsers et al.   EXPERIMENTAL DERMATOLOGY

Low Expression of the IL-23/Th17 Pathway in Atopic Dermatitis Compared to Psoriasis

(2014) E. Guttman-Yassky et al.   JOURNAL OF IMMUNOLOGY

Secukinumab in Plaque Psoriasis — Results of Two Phase 3 Trials

(2014) Richard G. Langley et al.   NEW ENGLAND JOURNAL OF MEDICINE

IL-17 Induces an Expanded Range of Downstream Genes in Reconstituted Human Epidermis Model

(2014) Andrea Chiricozzi et al.   PLoS One

IL-17 targeted therapies for psoriasis

(2013) Andrea Chiricozzi et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Treatment-Related Restoration of Langerhans Cell Migration in Psoriasis

(2013) Frances L. Shaw et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells

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The Emerging Role of IL-17 in the Pathogenesis of Psoriasis: Preclinical and Clinical Findings

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No impairment of monocyte-derived Langerhans cell phenotype or function in early-onset psoriasis

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Langerhans cells: critical regulators of skin immunity?

(2010) Björn E Clausen et al.   IMMUNOLOGY AND CELL BIOLOGY

Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis

(2010) Andrea Chiricozzi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Isolation and cultivation of human keratinocytes from skin or plucked hair for the generation of induced pluripotent stem cells

(2010) Trond Aasen et al.   Nature Protocols

Th17 Cytokines Stimulate CCL20 Expression in Keratinocytes In Vitro and In Vivo: Implications for Psoriasis Pathogenesis

(2009) Erin G. Harper et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY