Increased expression of interleukin-17 pathway genes in nonlesional skin of moderate-to-severe psoriasis vulgaris

Guselkumab (an IL-23–specific mAb) demonstrates clinical and molecular response in patients with moderate-to-severe psoriasis

(2014) Howard Sofen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

IL-17 Induces Inflammation-Associated Gene Products in Blood Monocytes, and Treatment with Ixekizumab Reduces Their Expression in Psoriasis Patient Blood

(2014) Claire Q.F. Wang et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-17 Induces an Expanded Range of Downstream Genes in Reconstituted Human Epidermis Model

(2014) Andrea Chiricozzi et al.   PLoS One

GSVA: gene set variation analysis for microarray and RNA-Seq data

(2013) Sonja Hänzelmann et al.   BMC BIOINFORMATICS

Dissecting the psoriasis transcriptome: inflammatory- and cytokine-driven gene expression in lesions from 163 patients

(2013) William R Swindell et al.   BMC GENOMICS

The IL-23/T17 pathogenic axis in psoriasis is amplified by keratinocyte responses

(2013) Michelle A. Lowes et al.   TRENDS IN IMMUNOLOGY

A Role for Epigenetics in Psoriasis: Methylated Cytosine–Guanine Sites Differentiate Lesional from Nonlesional Skin and from Normal Skin

(2012) Johann E. Gudjonsson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Expanding the Psoriasis Disease Profile: Interrogation of the Skin and Serum of Patients with Moderate-to-Severe Psoriasis

(2012) Mayte Suárez-Fariñas et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

The Emerging Role of IL-17 in the Pathogenesis of Psoriasis: Preclinical and Clinical Findings

(2012) David A. Martin et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Meta-Analysis Derived (MAD) Transcriptome of Psoriasis Defines the “Core” Pathogenesis of Disease

(2012) Suyan Tian et al.   PLoS One

A Subset of Methylated CpG Sites Differentiate Psoriatic from Normal Skin

(2011) Elisha D.O. Roberson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Transcriptional Profiling of Psoriasis Using RNA-seq Reveals Previously Unidentified Differentially Expressed Genes

(2011) Ali Jabbari et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-23 and IL-17A, but Not IL-12 and IL-22, Are Required for Optimal Skin Host Defense against Candida albicans

(2010) S. Kagami et al.   JOURNAL OF IMMUNOLOGY

Psoriasis and Systemic Inflammatory Diseases: Potential Mechanistic Links between Skin Disease and Co-Morbid Conditions

(2010) Batya B. Davidovici et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Assessment of the Psoriatic Transcriptome in a Large Sample: Additional Regulated Genes and Comparisons with In Vitro Models

(2010) Johann E. Gudjonsson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Integrative Responses to IL-17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis

(2010) Andrea Chiricozzi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Evaluation of the Psoriasis Transcriptome across Different Studies by Gene Set Enrichment Analysis (GSEA)

(2010) Mayte Suárez-Fariñas et al.   PLoS One

Serum cytokines and growth factor levels in Japanese patients with psoriasis

(2009) H. Takahashi et al.   CLINICAL AND EXPERIMENTAL DERMATOLOGY

Cytokine-Producing Dendritic Cells in the Pathogenesis of Inflammatory Skin Diseases

(2009) Leanne M. Johnson-Huang et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Global Gene Expression Analysis Reveals Evidence for Decreased Lipid Biosynthesis and Increased Innate Immunity in Uninvolved Psoriatic Skin

(2009) Johann E. Gudjonsson et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Circulating Th17, Th22, and Th1 Cells Are Increased in Psoriasis

(2009) Shinji Kagami et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

IL-17-producing CD8+ T lymphocytes from psoriasis skin plaques are cytotoxic effector cells that secrete Th17-related cytokines

(2009) Consuelo Ortega et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Serum Levels of IL-17 and IL-22 Are Reduced by Etanercept, but not by Acitretin, in Patients with Psoriasis: a Randomized-Controlled Trial

(2008) M. Caproni et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Psoriasis Vulgaris Lesions Contain Discrete Populations of Th1 and Th17 T Cells

(2008) Michelle A. Lowes et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Resident and “Inflammatory” Dendritic Cells in Human Skin

(2008) Lisa C. Zaba et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Type I Interferon: Potential Therapeutic Target for Psoriasis?

(2008) Yihong Yao et al.   PLoS One