Dissecting the pathobiology of altered MRI signal in amyotrophic lateral sclerosis: A post mortem whole brain sampling strategy for the integration of ultra-high-field MRI and quantitative neuropathology

Evaluating fibre orientation dispersion in white matter: Comparison of diffusion MRI, histology and polarized light imaging

(2017) Jeroen Mollink et al.   NEUROIMAGE

Apparatus for Histological Validation of In Vivo and Ex Vivo Magnetic Resonance Imaging of the Human Prostate

(2017) Roger M. Bourne et al.   Frontiers in Oncology

Widespread temporo-occipital lobe dysfunction in amyotrophic lateral sclerosis

(2017) Kristian Loewe et al.   Scientific Reports

Occipital cortical gyrification reductions associate with decreased functional connectivity in amyotrophic lateral sclerosis

(2016) Yuanchao Zhang et al.   Brain Imaging and Behavior

Comprehensive cellular-resolution atlas of the adult human brain

(2016) Song-Lin Ding et al.   JOURNAL OF COMPARATIVE NEUROLOGY

A large-scale multicentre cerebral diffusion tensor imaging study in amyotrophic lateral sclerosis

(2016) Hans-Peter Müller et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

The frontotemporal dementia-motor neuron disease continuum

(2016) James R Burrell et al.   LANCET

A comprehensive numerical analysis of background phase correction with V-SHARP

(2016) Pinar Senay Özbay et al.   NMR IN BIOMEDICINE

Contributions to magnetic susceptibility of brain tissue

(2016) Jeff H. Duyn et al.   NMR IN BIOMEDICINE

Working Memory Network Changes in ALS: An fMRI Study

(2016) Anne-Katrin Vellage et al.   Frontiers in Neuroscience

Magnetic susceptibility in the deep layers of the primary motor cortex in Amyotrophic Lateral Sclerosis

(2016) M. Costagli et al.   NeuroImage-Clinical

Whole-brain ex-vivo quantitative MRI of the cuprizone mouse model

(2016) Tobias C. Wood et al.   PeerJ

Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sclerosis: Evidence for clinico-pathologic subtypes

(2016) Ryoko Takeuchi et al.   Acta Neuropathologica Communications

Functional connectivity changes resemble patterns of pTDP-43 pathology in amyotrophic lateral sclerosis

(2016) Ines Schulthess et al.   Scientific Reports

Quantitative Susceptibility Mapping of the Motor Cortex in Amyotrophic Lateral Sclerosis and Primary Lateral Sclerosis

(2015) Andrew D. Schweitzer et al.   AMERICAN JOURNAL OF ROENTGENOLOGY

TDP-43 proteinopathies: pathological identification of brain regions differentiating clinical phenotypes

(2015) Rachel H. Tan et al.   BRAIN

Dentatorubrothalamic tract localization with postmortem MR diffusion tractography compared to histological 3D reconstruction

(2015) J. Mollink et al.   Brain Structure & Function

Semi-Automated Digital Image Analysis of Pick’s Disease and TDP-43 Proteinopathy

(2015) David J. Irwin et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Spreading of pathology in neurodegenerative diseases: a focus on human studies

(2015) Johannes Brettschneider et al.   NATURE REVIEWS NEUROSCIENCE

Applicability of digital analysis and imaging technology in neuropathology assessment

(2015) William D. Dunn et al.   NEUROPATHOLOGY

Streaking artifact reduction for quantitative susceptibility mapping of sources with large dynamic range

(2015) Hongjiang Wei et al.   NMR IN BIOMEDICINE

Executive Dysfunctions and Event-Related Brain Potentials in Patients with Amyotrophic Lateral Sclerosis

(2015) Caroline Seer et al.   Frontiers in Aging Neuroscience

Syntactic processing as a marker for cognitive impairment in amyotrophic lateral sclerosis

(2015) Stella Tsermentseli et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Disease-related microglia heterogeneity in the hippocampus of Alzheimer’s disease, dementia with Lewy bodies, and hippocampal sclerosis of aging

(2015) Adam D Bachstetter et al.   Acta Neuropathologica Communications

Spread of pathology in amyotrophic lateral sclerosis: assessment of phosphorylated TDP-43 along axonal pathways

(2015) Manaal Fatima et al.   Acta Neuropathologica Communications

Sequential distribution of pTDP-43 pathology in behavioral variant frontotemporal dementia (bvFTD)

(2014) Johannes Brettschneider et al.   ACTA NEUROPATHOLOGICA

TDP-43 is a key player in the clinical features associated with Alzheimer’s disease

(2014) Keith A. Josephs et al.   ACTA NEUROPATHOLOGICA

TDP-43 pathology and neuronal loss in amyotrophic lateral sclerosis spinal cord

(2014) Johannes Brettschneider et al.   ACTA NEUROPATHOLOGICA

Magnetic resonance imaging and histology correlation in the neocortex in temporal lobe epilepsy

(2014) Maged Goubran et al.   ANNALS OF NEUROLOGY

Myelination of the Nervous System: Mechanisms and Functions

(2014) Klaus-Armin Nave et al.   Annual Review of Cell and Developmental Biology

Syntactic Comprehension in Patients with Amyotrophic Lateral Sclerosis

(2014) Kentarou Yoshizawa et al.   BEHAVIOURAL NEUROLOGY

Diffusion tensor imaging analysis of sequential spreading of disease in amyotrophic lateral sclerosis confirms patterns of TDP-43 pathology

(2014) J. Kassubek et al.   BRAIN

Widespread grey matter pathology dominates the longitudinal cerebral MRI and clinical landscape of amyotrophic lateral sclerosis

(2014) Ricarda A. L. Menke et al.   BRAIN

Profiles of white matter tract pathology in frontotemporal dementia

(2014) Colin J. Mahoney et al.   HUMAN BRAIN MAPPING

Histological-MRI correlation in the primary motor cortex of patients with amyotrophic lateral sclerosis

(2014) Mark D. Meadowcroft et al.   JOURNAL OF MAGNETIC RESONANCE IMAGING

Postmortem Magnetic Resonance Imaging to Guide the Pathologic Cut

(2014) Martina Absinta et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Quantitative susceptibility mapping (QSM) of white matter multiple sclerosis lesions: Interpreting positive susceptibility and the presence of iron

(2014) Cynthia Wisnieff et al.   MAGNETIC RESONANCE IN MEDICINE

Improving diffusion-weighted imaging of post-mortem human brains: SSFP at 7T

(2014) Sean Foxley et al.   NEUROIMAGE

Functional pattern of brain FDG-PET in amyotrophic lateral sclerosis

(2014) M. Pagani et al.   NEUROLOGY

Impact of daily high-dose caffeine exposure on developing white matter of the immature ovine brain

(2014) Anzari Atik et al.   PEDIATRIC RESEARCH

Histological Quantitation of Brain Injury Using Whole Slide Imaging: A Pilot Validation Study in Mice

(2014) Zhenzhou Chen et al.   PLoS One

White Matter Tract Damage in the Behavioral Variant of Frontotemporal and Corticobasal Dementia Syndromes

(2014) Fernanda Tovar-Moll et al.   PLoS One

Postmortem examination of patient H.M.’s brain based on histological sectioning and digital 3D reconstruction

(2014) Jacopo Annese et al.   Nature Communications

Stages of pTDP-43 pathology in amyotrophic lateral sclerosis

(2013) Johannes Brettschneider et al.   ANNALS OF NEUROLOGY

Diagnosis and Management of Behavioral Variant Frontotemporal Dementia

(2013) Peter S. Pressman et al.   BIOLOGICAL PSYCHIATRY

MRI measures of corpus callosum iron and myelin in early Huntington's disease

(2013) M. Di Paola et al.   HUMAN BRAIN MAPPING

Comparison of Histological Techniques to Visualize Iron in Paraffin-embedded Brain Tissue of Patients with Alzheimer’s Disease

(2013) Sara van Duijn et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

The p38  MAPK Regulates Microglial Responsiveness to Diffuse Traumatic Brain Injury

(2013) A. D. Bachstetter et al.   JOURNAL OF NEUROSCIENCE

Amyotrophic lateral sclerosis—a model of corticofugal axonal spread

(2013) Heiko Braak et al.   Nature Reviews Neurology

Iron metabolism in the CNS: implications for neurodegenerative diseases

(2013) Tracey A. Rouault   NATURE REVIEWS NEUROSCIENCE

Increased number of astrocytes and macrophages/microglial cells in the corpus callosum in amyotrophic lateral sclerosis

(2013) Mikiko Sugiyama et al.   NEUROPATHOLOGY

Accelerating Fibre Orientation Estimation from Diffusion Weighted Magnetic Resonance Imaging Using GPUs

(2013) Moisés Hernández et al.   PLoS One

Cortical Thinning and Clinical Heterogeneity in Amyotrophic Lateral Sclerosis

(2013) Domenico Maria Mezzapesa et al.   PLoS One

BigBrain: An Ultrahigh-Resolution 3D Human Brain Model

(2013) K. Amunts et al.   SCIENCE

Deciphering amyotrophic lateral sclerosis: What phenotype, neuropathology and genetics are telling us about pathogenesis

(2013) John Ravits et al.   Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration

Classification of FTLD-TDP cases into pathological subtypes using antibodies against phosphorylated and non-phosphorylated TDP43

(2013) Rachel H Tan et al.   Acta Neuropathologica Communications

In vivo and post-mortem memory circuit integrity in frontotemporal dementia and Alzheimer’s disease

(2012) Michael Hornberger et al.   BRAIN

A combined post-mortem magnetic resonance imaging and quantitative histological study of multiple sclerosis pathology

(2012) James Kolasinski et al.   BRAIN

Grey matter correlates of clinical variables in amyotrophic lateral sclerosis (ALS): a neuroimaging study of ALS motor phenotype heterogeneity and cortical focality

(2012) P. Bede et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

A Quantitative Postmortem MRI Design Sensitive to White Matter Hyperintensity Differences and Their Relationship With Underlying Pathology

(2012) Melissa E. Murray et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Early Stage Drug Treatment That Normalizes Proinflammatory Cytokine Production Attenuates Synaptic Dysfunction in a Mouse Model That Exhibits Age-Dependent Progression of Alzheimer's Disease-Related Pathology

(2012) A. D. Bachstetter et al.   JOURNAL OF NEUROSCIENCE

MIND: Modality independent neighbourhood descriptor for multi-modal deformable registration

(2012) Mattias P. Heinrich et al.   MEDICAL IMAGE ANALYSIS

Iron Accumulation in Deep Cortical Layers Accounts for MRI Signal Abnormalities in ALS: Correlating 7 Tesla MRI and Pathology

(2012) Justin Y. Kwan et al.   PLoS One

Microglial Activation Correlates with Disease Progression and Upper Motor Neuron Clinical Symptoms in Amyotrophic Lateral Sclerosis

(2012) Johannes Brettschneider et al.   PLoS One

The importance of combining MRI and large-scale digital histology in neuroimaging studies of brain connectivity and disease

(2012) Jacopo Annese   Frontiers in Neuroinformatics

Convergent grey and white matter evidence of orbitofrontal cortex changes related to disinhibition in behavioural variant frontotemporal dementia

(2011) Michael Hornberger et al.   BRAIN

Tracking iron in multiple sclerosis: a combined imaging and histopathological study at 7 Tesla

(2011) F. Bagnato et al.   BRAIN

The NumPy Array: A Structure for Efficient Numerical Computation

(2011) Stéfan van der Walt et al.   COMPUTING IN SCIENCE & ENGINEERING

Amyotrophic lateral sclerosis

(2011) Matthew C Kiernan et al.   LANCET

Diffusion tractography of post-mortem human brains: Optimization and comparison of spin echo and steady-state free precession techniques

(2011) Karla L. Miller et al.   NEUROIMAGE

FSL

(2011) Mark Jenkinson et al.   NEUROIMAGE

The contributions of myelin and axonal caliber to transverse relaxation time in shiverer and neurofilament-deficient mouse models

(2010) Victor V. Dyakin et al.   NEUROIMAGE

Corpus callosum involvement is a consistent feature of amyotrophic lateral sclerosis

(2010) N. Filippini et al.   NEUROLOGY

Steady-state diffusion-weighted imaging: theory, acquisition and analysis

(2010) Jennifer A. McNab et al.   NMR IN BIOMEDICINE

Distinct and Overlapping Functional Zones in the Cerebellum Defined by Resting State Functional Connectivity

(2009) Jill X. O'Reilly et al.   CEREBRAL CORTEX

Cellular Inflammatory Response to Flaviviruses in the Central Nervous System of a Primate Host

(2009) Olga A. Maximova et al.   JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY

Accurate and robust brain image alignment using boundary-based registration

(2009) Douglas N. Greve et al.   NEUROIMAGE

High resolution diffusion-weighted imaging in fixed human brain using diffusion-weighted steady state free precession

(2009) Jennifer A. McNab et al.   NEUROIMAGE

Evidence of Multisystem Disorder in Whole-Brain Map of Pathological TDP-43 in Amyotrophic Lateral Sclerosis

(2008) Felix Geser et al.   ARCHIVES OF NEUROLOGY

Signs of impaired selective attention in patients with amyotrophic lateral sclerosis

(2008) E. H. Pinkhardt et al.   JOURNAL OF NEUROLOGY