Sustained high glucose exposure sensitizes macrophage responses to cytokine stimuli but reduces their phagocytic activity

Higher phagocytic activity of thioglycollate-elicited peritoneal macrophages is related to metabolic status of the cells

(2017) Sofia Pavlou et al.   Journal of Inflammation-London

Macrophage Immunometabolism: Where Are We (Going)?

(2017) Jan Van den Bossche et al.   TRENDS IN IMMUNOLOGY

Diabetic retinopathy and dysregulated innate immunity

(2017) Heping Xu et al.   VISION RESEARCH

Pyruvate Kinase M2 Regulates Hif-1α Activity and IL-1β Induction and Is a Critical Determinant of the Warburg Effect in LPS-Activated Macrophages

(2015) Eva M. Palsson-McDermott et al.   Cell Metabolism

Role of the receptor for advanced glycation endproducts (RAGE) in retinal vasodegenerative pathology during diabetes in mice

(2015) Carmel M. McVicar et al.   DIABETOLOGIA

Immunometabolism governs dendritic cell and macrophage function

(2015) Luke A.J. O’Neill et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Regulation of Inflammatory Phenotype in Macrophages by a Diabetes-Induced Long Noncoding RNA

(2014) M. A. Reddy et al.   DIABETES

Metabolic Reprogramming of Macrophages

(2014) Alex J. Freemerman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Modulation of Immune Response by RAGE and TLR4 Signalling in PBMCs of Diabetic and Non-Diabetic Patients

(2014) S. C. T. Frasnelli et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

Myeloid cell dysfunction and the pathogenesis of the diabetic chronic wound

(2014) Kate Wicks et al.   SEMINARS IN IMMUNOLOGY

Diabetes induces stable intrinsic changes to myeloid cells that contribute to chronic inflammation during wound healing in mice

(2013) P. Bannon et al.   Disease Models & Mechanisms

Accumulation of M1-like macrophages in type 2 diabetic islets is followed by a systemic shift in macrophage polarization

(2013) H. Cucak et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Metabolism of inflammation limited by AMPK and pseudo-starvation

(2013) Luke A. J. O'Neill et al.   NATURE

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

(2013) G. M. Tannahill et al.   NATURE

CD11b + Bone Marrow–Derived Monocytes Are the Major Leukocyte Subset Responsible for Retinal Capillary Leukostasis in Experimental Diabetes in Mouse and Express High Levels of CCR5 in the Circulation

(2012) Andreia M. Serra et al.   AMERICAN JOURNAL OF PATHOLOGY

Long-term type 1 diabetes influences haematopoietic stem cells by reducing vascular repair potential and increasing inflammatory monocyte generation in a murine model

(2012) S. Hazra et al.   DIABETOLOGIA

Expression of Complement Components and Regulators by Different Subtypes of Bone Marrow-Derived Macrophages

(2012) Chang Luo et al.   INFLAMMATION

High glucose stimulates TNFα and MCP-1 expression in rat microglia via ROS and NF-κB pathways

(2011) Yi Quan et al.   ACTA PHARMACOLOGICA SINICA

Dysregulation in Retinal Para-Inflammation and Age-Related Retinal Degeneration in CCL2 or CCR2 Deficient Mice

(2011) Mei Chen et al.   PLoS One

Inflammation in diabetic retinopathy

(2011) Johnny Tang et al.   PROGRESS IN RETINAL AND EYE RESEARCH

Natural therapeutic magnesium lithospermate B potently protects the endothelium from hyperglycaemia-induced dysfunction

(2010) So Hun Kim et al.   CARDIOVASCULAR RESEARCH

Diabetes Mellitus Induces Bone Marrow Microangiopathy

(2009) Atsuhiko Oikawa et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Mechanism of Oxidative DNA Damage in Diabetes: Tuberin Inactivation and Downregulation of DNA Repair Enzyme 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine-DNA Glycosylase

(2008) S. Simone et al.   DIABETES

A quantitative comparison of rates of phagocytosis and digestion of apoptotic cells by macrophages from normal (BALB/c) and diabetes-prone (NOD) mice

(2007) Athanasius F. M. Marée et al.   JOURNAL OF APPLIED PHYSIOLOGY