The whole transcriptome effects of the PPARα agonist fenofibrate on livers of hepatocyte humanized mice

Insights into the role of hepatocyte PPARα activity in response to fasting

(2018) Marion Régnier et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Genomewide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR and PPARα in primary human hepatocytes

(2016) Benjamin A. Kandel et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

PPARs in obesity-induced T2DM, dyslipidaemia and NAFLD

(2016) Barbara Gross et al.   Nature Reviews Endocrinology

Enrichr: a comprehensive gene set enrichment analysis web server 2016 update

(2016) Maxim V. Kuleshov et al.   NUCLEIC ACIDS RESEARCH

The impact of PPARα activation on whole genome gene expression in human precision cut liver slices

(2015) Aafke W.F. Janssen et al.   BMC GENOMICS

Transcriptomic signatures of peroxisome proliferator-activated receptor α (PPARα) in different mouse liver models identify novel aspects of its biology

(2015) Ewa Szalowska et al.   BMC GENOMICS

Generation of Novel Chimeric Mice with Humanized Livers by Using Hemizygous cDNA-uPA/SCID Mice

(2015) Chise Tateno et al.   PLoS One

Chimeric Mice with Hepatocyte-humanized Liver as an Appropriate Model to Study Human Peroxisome Proliferator–activated Receptor-α

(2014) Chise Tateno et al.   TOXICOLOGIC PATHOLOGY

Integrated physiology and systems biology of PPARα

(2014) Sander Kersten   Molecular Metabolism

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool

(2013) Edward Y Chen et al.   BMC BIOINFORMATICS

DNA Methylation Analysis in Nonalcoholic Fatty Liver Disease Suggests Distinct Disease-Specific and Remodeling Signatures after Bariatric Surgery

(2013) Markus Ahrens et al.   Cell Metabolism

Mode of action framework analysis for receptor-mediated toxicity: The peroxisome proliferator-activated receptor alpha (PPARα) as a case study

(2013) J. Christopher Corton et al.   CRITICAL REVIEWS IN TOXICOLOGY

Plasma mannose-binding lectin is stimulated by PPARα in humans

(2012) Maryam Rakhshandehroo et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Mechanisms of Gene Regulation by Fatty Acids

(2012) Anastasia Georgiadi et al.   Advances in Nutrition

PPARs are a unique set of fatty acid regulated transcription factors controlling both lipid metabolism and inflammation

(2011) Tamas Varga et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Growth Hormone-Dependent Pathogenesis of Human Hepatic Steatosis in a Novel Mouse Model Bearing a Human Hepatocyte-Repopulated Liver

(2011) Chise Tateno et al.   ENDOCRINOLOGY

Comparative transcriptomic and metabolomic analysis of fenofibrate and fish oil treatments in mice

(2011) Yingchang Lu et al.   PHYSIOLOGICAL GENOMICS

Profiling of promoter occupancy by PPARα in human hepatoma cells via ChIP-chip analysis

(2010) David L. M. van der Meer et al.   NUCLEIC ACIDS RESEARCH

Caloric Restriction and Exercise Increase Plasma ANGPTL4 Levels in Humans via Elevated Free Fatty Acids

(2009) Sander Kersten et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Comparative Analysis of Gene Regulation by the Transcription Factor PPARα between Mouse and Human

(2009) Maryam Rakhshandehroo et al.   PLoS One