Transcriptomic signatures of peroxisome proliferator-activated receptor α (PPARα) in different mouse liver models identify novel aspects of its biology

Model Steatogenic Compounds (Amiodarone, Valproic Acid, and Tetracycline) Alter Lipid Metabolism by Different Mechanisms in Mouse Liver Slices

(2014) Ewa Szalowska et al.   PLoS One

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of hepatotoxicity, cell signaling and ADME

(2013) Patricio Godoy et al.   ARCHIVES OF TOXICOLOGY

Exosomes as new vesicular lipid transporters involved in cell–cell communication and various pathophysiologies

(2013) Michel Record et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS

Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis

(2013) Bart Staels et al.   HEPATOLOGY

Role of Angptl4 in vascular permeability and inflammation

(2013) Liang Guo et al.   INFLAMMATION RESEARCH

Nuclear receptor atlas of female mouse liver parenchymal, endothelial, and Kupffer cells

(2013) Zhaosha Li et al.   PHYSIOLOGICAL GENOMICS

Pathogenic role of diabetes-induced PPAR-  down-regulation in microvascular dysfunction

(2013) Y. Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immune cells and metabolic dysfunction

(2013) Ashley Eheim et al.   Seminars in Immunopathology

Endothelium as a gatekeeper of fatty acid transport

(2013) Devi Mehrotra et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

PPARα agonist Wy14643 suppresses cathepsin B in human endothelial cells via transcriptional, post-transcriptional and post-translational mechanisms

(2012) Gabi Reichenbach et al.   ANGIOGENESIS

Kupffer cells suppress perfluorononanoic acid-induced hepatic peroxisome proliferator-activated receptor α expression by releasing cytokines

(2012) Xuemei Fang et al.   ARCHIVES OF TOXICOLOGY

Inflammation and Lipid Signaling in the Etiology of Insulin Resistance

(2012) Christopher K. Glass et al.   Cell Metabolism

PPARβ/δ affects pancreatic β cell mass and insulin secretion in mice

(2012) José Iglesias et al.   JOURNAL OF CLINICAL INVESTIGATION

Vagus Nerve Stimulation Reduces Body Weight and Fat Mass in Rats

(2012) Sebastiano Banni et al.   PLoS One

PPARs at the crossroads of lipid signaling and inflammation

(2012) Walter Wahli et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays

(2010) Yi Qu et al.   BMC BIOINFORMATICS

Preparation and incubation of precision-cut liver and intestinal slices for application in drug metabolism and toxicity studies

(2010) Inge A M de Graaf et al.   Nature Protocols

Kupffer cells promote hepatic steatosis via interleukin-1β-dependent suppression of peroxisome proliferator-activated receptor α activity

(2009) Rinke Stienstra et al.   HEPATOLOGY

Comparative Analysis of Gene Regulation by the Transcription Factor PPARα between Mouse and Human

(2009) Maryam Rakhshandehroo et al.   PLoS One

Fatty acid transport and activation and the expression patterns of genes involved in fatty acid trafficking

(2008) Angel Sandoval et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

A comparison of meta-analysis methods for detecting differentially expressed genes in microarray experiments

(2008) Fangxin Hong et al.   BIOINFORMATICS

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH