Somatic evolutionary timings of driver mutations

Functional variomics and network perturbation: connecting genotype to phenotype in cancer

(2017) Song Yi et al.   NATURE REVIEWS GENETICS

Reconstructing metastatic seeding patterns of human cancers

(2017) Johannes G. Reiter et al.   Nature Communications

Evaluation of three read-depth based CNV detection tools using whole-exome sequencing data

(2017) Ruen Yao et al.   Molecular Cytogenetics

The challenges of tumor genetic diversity

(2016) Edmund A. Mroz et al.   CANCER

Multiregion Whole-Exome Sequencing Uncovers the Genetic Evolution and Mutational Heterogeneity of Early-Stage Metastatic Melanoma

(2016) K. Harbst et al.   CANCER RESEARCH

Deciphering intratumor heterogeneity using cancer genome analysis

(2016) Daeun Ryu et al.   HUMAN GENETICS

Multiregion sequencing reveals the intratumor heterogeneity of driver mutations in TP53-driven non-small cell lung cancer

(2016) Le-Le Zhang et al.   INTERNATIONAL JOURNAL OF CANCER

The genomic landscape and evolution of endometrial carcinoma progression and abdominopelvic metastasis

(2016) William J Gibson et al.   NATURE GENETICS

Identification of neutral tumor evolution across cancer types

(2016) Marc J Williams et al.   NATURE GENETICS

Early and multiple origins of metastatic lineages within primary tumors

(2016) Zi-Ming Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Integrated Multiregional Analysis Proposing a New Model of Colorectal Cancer Evolution

(2016) Ryutaro Uchi et al.   PLoS Genetics

Tumor evolution and intratumor heterogeneity of an epithelial ovarian cancer investigated using next-generation sequencing

(2015) Jung-Yun Lee et al.   BMC CANCER

Biological and Therapeutic Impact of Intratumor Heterogeneity in Cancer Evolution

(2015) Nicholas McGranahan et al.   CANCER CELL

Inferring the Origin of Metastases from Cancer Phylogenies

(2015) W. S. Hong et al.   CANCER RESEARCH

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution

(2015) Hoon Kim et al.   GENOME RESEARCH

Clonally related uterine leiomyomas are common and display branched tumor evolution

(2015) Miika Mehine et al.   HUMAN MOLECULAR GENETICS

Intra-tumor genetic heterogeneity in rectal cancer

(2015) Karin M Hardiman et al.   LABORATORY INVESTIGATION

The evolutionary history of lethal metastatic prostate cancer

(2015) Gunes Gundem et al.   NATURE

Identifying recurrent mutations in cancer reveals widespread lineage diversity and mutational specificity

(2015) Matthew T Chang et al.   NATURE BIOTECHNOLOGY

Paired exome analysis of Barrett's esophagus and adenocarcinoma

(2015) Matthew D Stachler et al.   NATURE GENETICS

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

(2015) Lucy R Yates et al.   NATURE MEDICINE

Ensembl 2016

(2015) Andrew Yates et al.   NUCLEIC ACIDS RESEARCH

Clonal status of actionable driver events and the timing of mutational processes in cancer evolution

(2015) Nicholas McGranahan et al.   Science Translational Medicine

Clonal expansion and linear genome evolution through breast cancer progression from pre-invasive stages to asynchronous metastasis

(2015) Anne Bruun Krøigård et al.   Oncotarget

Clonality and Evolutionary History of Rhabdomyosarcoma

(2015) Li Chen et al.   PLoS Genetics

Multiple region whole-exome sequencing reveals dramatically evolving intratumor genomic heterogeneity in esophageal squamous cell carcinoma

(2015) W Cao et al.   Oncogenesis

Genomic architecture and evolution of clear cell renal cell carcinomas defined by multiregion sequencing

(2014) Marco Gerlinger et al.   NATURE GENETICS

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

(2014) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

Intratumor heterogeneity in localized lung adenocarcinomas delineated by multiregion sequencing

(2014) J. Zhang et al.   SCIENCE

Hierarchy in somatic mutations arising during genomic evolution and progression of follicular lymphoma

(2013) M. R. Green et al.   BLOOD

Genome evolution during progression to breast cancer

(2013) D. E. Newburger et al.   GENOME RESEARCH

Distinct evolutionary trajectories of primary high-grade serous ovarian cancers revealed through spatial mutational profiling

(2013) Ali Bashashati et al.   JOURNAL OF PATHOLOGY

The Cancer Genome Atlas Pan-Cancer analysis project

(2013) John N Weinstein et al.   NATURE GENETICS

IntOGen-mutations identifies cancer drivers across tumor types

(2013) Abel Gonzalez-Perez et al.   NATURE METHODS

Mutational Analysis Reveals the Origin and Therapy-Driven Evolution of Recurrent Glioma

(2013) B. E. Johnson et al.   SCIENCE

Estimating the order of mutations during tumorigenesis from tumor genome sequencing data

(2012) Ahrim Youn et al.   BIOINFORMATICS

The Life History of 21 Breast Cancers

(2012) Serena Nik-Zainal et al.   CELL

Whole-genome sequencing of liver cancers identifies etiological influences on mutation patterns and recurrent mutations in chromatin regulators

(2012) Akihiro Fujimoto et al.   NATURE GENETICS

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

Single-cell sequencing analysis characterizes common and cell-lineage-specific mutations in a muscle-invasive bladder cancer

(2012) Yingrui Li et al.   GigaScience

Distinguishing Driver and Passenger Mutations in an Evolutionary History Categorized by Interference

(2011) Christopher J. R. Illingworth et al.   GENETICS

The cancer genome

(2009) Michael R. Stratton et al.   NATURE

Subclonal phylogenetic structures in cancer revealed by ultra-deep sequencing

(2008) P. J. Campbell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA