Suppressing aberrant GluN3A expression rescues synaptic and behavioral impairments in Huntington's disease models

The NMDA receptor subunit GluN3A protects against 3-nitroproprionic-induced striatal lesions via inhibition of calpain activation

(2012) Rebeca Martínez-Turrillas et al.   NEUROBIOLOGY OF DISEASE

Conditional BDNF release under pathological conditions improves Huntington's disease pathology by delaying neuronal dysfunction

(2011) Albert Giralt et al.   Molecular Neurodegeneration

Identification of anti-inflammatory targets for Huntington's disease using a brain slice-based screening assay

(2011) Peter H. Reinhart et al.   NEUROBIOLOGY OF DISEASE

Alterations in Striatal Synaptic Transmission are Consistent across Genetic Mouse Models of Huntington's Disease

(2010) Damian M Cummings et al.   ASN Neuro

Phenylbutyrate rescues dendritic spine loss associated with memory deficits in a mouse model of Alzheimer disease

(2010) Ana Ricobaraza et al.   HIPPOCAMPUS

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Early Increase in Extrasynaptic NMDA Receptor Signaling and Expression Contributes to Phenotype Onset in Huntington's Disease Mice

(2010) Austen J. Milnerwood et al.   NEURON

Influence of the NR3A subunit on NMDA receptor functions

(2010) Maile A. Henson et al.   PROGRESS IN NEUROBIOLOGY

Differential Susceptibility to Excitotoxic Stress in YAC128 Mouse Models of Huntington Disease between Initiation and Progression of Disease

(2009) R. K. Graham et al.   JOURNAL OF NEUROSCIENCE

Neuroprotection by the NR3A Subunit of the NMDA Receptor

(2009) N. Nakanishi et al.   JOURNAL OF NEUROSCIENCE

Mutant Huntingtin Impairs Vesicle Formation from Recycling Endosomes by Interfering with Rab11 Activity

(2009) X. Li et al.   MOLECULAR AND CELLULAR BIOLOGY

Balance between synaptic versus extrasynaptic NMDA receptor activity influences inclusions and neurotoxicity of mutant huntingtin

(2009) Shu-ichi Okamoto et al.   NATURE MEDICINE

Downregulation of NR3A-Containing NMDARs Is Required for Synapse Maturation and Memory Consolidation

(2009) Adam C. Roberts et al.   NEURON

A Comparison of Huntington Disease and Huntington Disease-Like 2 Neuropathology

(2008) Dobrila D. Rudnicki et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Opposing effects of polyglutamine expansion on native protein complexes contribute to SCA1

(2008) Janghoo Lim et al.   NATURE