Evaluation of differences between dual salt-pH gradient elution and mono gradient elution using a thermodynamic model: Simultaneous separation of six monoclonal antibody charge and size variants on preparative-scale ion exchange chromatographic resin

Modeling of dual gradient elution in ion exchange and mixed-mode chromatography

(2015) Yi Feng Lee et al.   JOURNAL OF CHROMATOGRAPHY A

Solvent modulated linear pH gradient elution for the purification of conventional and bispecific antibodies: Modeling and application

(2015) Simon Kluters et al.   JOURNAL OF CHROMATOGRAPHY A

Application of linear pH gradients for the modeling of ion exchange chromatography: Separation of monoclonal antibody monomer from aggregates

(2015) Simon Kluters et al.   JOURNAL OF SEPARATION SCIENCE

Assessment of chemical modifications of sites in the CDRs of recombinant antibodies

(2014) Markus Haberger et al.   mAbs

Biopharmaceutical benchmarks 2014

(2014) Gary Walsh   NATURE BIOTECHNOLOGY

Modeling of salt and pH gradient elution in ion-exchange chromatography

(2013) Michael Schmidt et al.   JOURNAL OF SEPARATION SCIENCE

Therapeutic application of monoclonal antibodies in cancer: advances and challenges

(2012) H. Modjtahedi et al.   BRITISH MEDICAL BULLETIN

N-terminal Glutamate to Pyroglutamate Conversionin Vivofor Human IgG2 Antibodies

(2011) Y. Diana Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Influence of protein and stationary phase properties on protein–matrix-interaction in cation exchange chromatography

(2011) Marina Urmann et al.   JOURNAL OF CHROMATOGRAPHY A

Fragmentation of monoclonal antibodies

(2011) Josef Vlasak et al.   mAbs

Analytical methods for physicochemical characterization of antibody drug conjugates

(2011) Aditya Wakankar et al.   mAbs

What's fueling the biotech engine—2010 to 2011

(2011) Saurabh Aggarwal   NATURE BIOTECHNOLOGY

Isoelectric point, electric charge, and nomenclature of the acid-base residues of proteins

(2010) Andrés A. Maldonado et al.   BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION

Recent advances in large-scale production of monoclonal antibodies and related proteins

(2010) Abhinav A. Shukla et al.   TRENDS IN BIOTECHNOLOGY

Multiproduct High-Resolution Monoclonal Antibody Charge Variant Separations by pH Gradient Ion-Exchange Chromatography

(2009) Dell Farnan et al.   ANALYTICAL CHEMISTRY

Quantitative analysis of monoclonal antibodies by cation-exchange chromatofocusing

(2009) Anna Rozhkova   JOURNAL OF CHROMATOGRAPHY A

A Review of the Thermodynamics of Protein Association to Ligands, Protein Adsorption, and Adsorption Isotherms

(2008) J. M. Mollerup   CHEMICAL ENGINEERING & TECHNOLOGY

Theory and applications of a novel ion exchange chromatographic technology using controlled pH gradients for separating proteins on anionic and cationic stationary phases

(2008) Latchezar I. Tsonev et al.   JOURNAL OF CHROMATOGRAPHY A