Melatonin Rescues Mesenchymal Stem Cells from Senescence Induced by the Uremic Toxin p-Cresol via Inhibiting mTOR-Dependent Autophagy

Salmonella Typhimurium disrupts Sirt1/AMPK checkpoint control of mTOR to impair autophagy

(2017) Raja Ganesan et al.   PLoS Pathogens

Melatonin ameliorates myocardial ischemia/reperfusion injury in type 1 diabetic rats by preserving mitochondrial function: role of AMPK-PGC-1α-SIRT3 signaling

(2017) Liming Yu et al.   Scientific Reports

Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways

(2016) Lisa A. Lesniewski et al.   AGING CELL

Zika Virus NS4A and NS4B Proteins Deregulate Akt-mTOR Signaling in Human Fetal Neural Stem Cells to Inhibit Neurogenesis and Induce Autophagy

(2016) Qiming Liang et al.   Cell Stem Cell

Endothelial Microparticles From Acute Coronary Syndrome Patients Induce Premature Coronary Artery Endothelial Cell Aging and ThrombogenicityClinical Perspective

(2016) Malak Abbas et al.   CIRCULATION

The cardioprotective effect of melatonin and exendin-4 treatment in a rat model of cardiorenal syndrome

(2016) Sarah Chua et al.   JOURNAL OF PINEAL RESEARCH

p-Cresyl sulfate affects the oxidative burst, phagocytosis process, and antigen presentation of monocyte-derived macrophages

(2016) M.L.V. Azevedo et al.   TOXICOLOGY LETTERS

Celecoxib inhibits proliferation and survival of chronic myelogeous leukemia (CML) cells via AMPK-dependent regulation of β-catenin and mTORC1/2

(2016) Beatrice Riva et al.   Oncotarget

Anabolism-Associated Mitochondrial Stasis Driving Lymphocyte Differentiation over Self-Renewal

(2016) William C. Adams et al.   Cell Reports

Non-Thermal Atmospheric Pressure Plasma Efficiently Promotes the Proliferation of Adipose Tissue-Derived Stem Cells by Activating NO-Response Pathways

(2016) Jeongyeon Park et al.   Scientific Reports

Slow intestinal transit contributes to elevate urinaryp-cresol level in Italian autistic children

(2015) Stefano Gabriele et al.   Autism Research

Targeting molecules to medicine with mTOR, autophagy and neurodegenerative disorders

(2015) Kenneth Maiese   BRITISH JOURNAL OF CLINICAL PHARMACOLOGY

Melatonin and endoplasmic reticulum stress: relation to autophagy and apoptosis

(2015) Anna Fernández et al.   JOURNAL OF PINEAL RESEARCH

p-Cresol mediates autophagic cell death in renal proximal tubular cells

(2015) Hsin-Hung Lin et al.   TOXICOLOGY LETTERS

Targeting AMPK for cancer prevention and treatment

(2015) Weidong Li et al.   Oncotarget

Cytotoxic Effects ofp-Cresol in Renal Epithelial Tubular Cells

(2014) Alessandra Brocca et al.   BLOOD PURIFICATION

Extrapineal melatonin: sources, regulation, and potential functions

(2014) Darío Acuña-Castroviejo et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Melatonin Inhibits mTOR-Dependent Autophagy during Liver Ischemia/Reperfusion

(2014) Jung-Woo Kang et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Involvement of autophagy in melatonin-induced cytotoxicity in glioma-initiating cells

(2014) Vanesa Martín et al.   JOURNAL OF PINEAL RESEARCH

Melatonin enhances the human mesenchymal stem cells motility via melatonin receptor 2 coupling with Gαq in skin wound healing

(2014) Sei-Jung Lee et al.   JOURNAL OF PINEAL RESEARCH

p-Cresol Affects Reactive Oxygen Species Generation, Cell Cycle Arrest, Cytotoxicity and Inflammation/Atherosclerosis-Related Modulators Production in Endothelial Cells and Mononuclear Cells

(2014) Mei-Chi Chang et al.   PLoS One

Uremic Toxin p-Cresol Induces Akt-Pathway-Selective Insulin Resistance in Bone Marrow-Derived Mesenchymal Stem Cells

(2014) Hyunjin Noh et al.   STEM CELLS

p -Cresyl sulfate causes renal tubular cell damage by inducing oxidative stress by activation of NADPH oxidase

(2013) Hiroshi Watanabe et al.   KIDNEY INTERNATIONAL

An update on uremic toxins

(2012) N. Neirynck et al.   INTERNATIONAL UROLOGY AND NEPHROLOGY

Melatonin-induced autophagy is associated with degradation of MyoD protein in C2C12 myoblast cells

(2012) Chi Hyun Kim et al.   JOURNAL OF PINEAL RESEARCH

mTOR-regulated senescence and autophagy during reprogramming of somatic cells to pluripotency: A roadmap from energy metabolism to stem cell renewal and aging

(2011) Javier A. Menendez et al.   CELL CYCLE

Melatonin promotes proliferation and differentiation of neural stem cells subjected to hypoxia in vitro

(2011) Jie Fu et al.   JOURNAL OF PINEAL RESEARCH

The Role of Autophagy in Cancer: Therapeutic Implications

(2011) Z. J. Yang et al.   MOLECULAR CANCER THERAPEUTICS

p-Cresol and Cardiovascular Risk in Mild-to-Moderate Kidney Disease

(2010) B. K. I. Meijers et al.   Clinical Journal of the American Society of Nephrology

Pathophysiological significance of senescence marker protein-30

(2010) Naoki Maruyama et al.   Geriatrics & Gerontology International

Melatonin protects against apoptotic and autophagic cell death in C2C12 murine myoblast cells

(2010) Chi Hyun Kim et al.   JOURNAL OF PINEAL RESEARCH

Melatonin inhibits adipogenesis and enhances osteogenesis of human mesenchymal stem cells by suppressing PPARγ expression and enhancing Runx2 expression

(2010) Liangming Zhang et al.   JOURNAL OF PINEAL RESEARCH

Association of reactive oxygen species levels and radioresistance in cancer stem cells

(2009) Maximilian Diehn et al.   NATURE

Role of HIF-1α and VEGF in human mesenchymal stem cell proliferation by 17β-estradiol: involvement of PKC, PI3K/Akt, and MAPKs

(2008) Seung Pil Yun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Human mesenchymal stem cells isolated from the umbilical cord

(2007) C QIAO et al.   CELL BIOLOGY INTERNATIONAL

Cytochrome c-mediated oxidation of hydroethidine and mito-hydroethidine in mitochondria: Identification of homo- and heterodimers

(2007) Jacek Zielonka et al.   FREE RADICAL BIOLOGY AND MEDICINE