Enalapril decreases rat plasma concentration of TMAO, a gut bacteria-derived cardiovascular marker

Trimethylamine N -oxide: A harmful, protective or diagnostic marker in lifestyle diseases?

(2018) Artur Nowiński et al.   NUTRITION

Indole and indoxyl sulfate, gut bacteria metabolites of tryptophan, change arterial blood pressure via peripheral and central mechanisms in rats

(2018) Tomasz Huć et al.   PHARMACOLOGICAL RESEARCH

Targeting of microbe-derived metabolites to improve human health: The next frontier for drug discovery

(2017) J. Mark Brown et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Involvement of Organic Cation Transporters in the Kinetics of Trimethylamine N-oxide

(2017) Takeshi Miyake et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

Microbiome perturbation by oral vancomycin reduces plasma concentration of two gut-derived uremic solutes, indoxyl sulfate and p-cresyl sulfate, in end-stage renal disease

(2017) Lama Nazzal et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

Renin angiotensin aldosterone inhibition in the treatment of cardiovascular disease

(2017) Carlos M. Ferrario et al.   PHARMACOLOGICAL RESEARCH

Hypertension in rats is associated with an increased permeability of the colon to TMA, a gut bacteria metabolite

(2017) Kinga Jaworska et al.   PLoS One

Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria

(2017) Marina Makrecka-Kuka et al.   TOXICOLOGY LETTERS

Increased Trimethylamine N- Oxide Portends High Mortality Risk Independent of Glycemic Control in Patients with Type 2 Diabetes Mellitus

(2016) W. H. Wilson Tang et al.   CLINICAL CHEMISTRY

Diabetes is Associated with Higher Trimethylamine N-oxide Plasma Levels

(2016) M. Dambrova et al.   EXPERIMENTAL AND CLINICAL ENDOCRINOLOGY & DIABETES

Intracolonic hydrogen sulfide lowers blood pressure in rats

(2016) Lenka Tomasova et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Repeated restraint stress produces acute and chronic changes in hemodynamic parameters in rats

(2016) Mariusz Sikora et al.   STRESS-THE INTERNATIONAL JOURNAL ON THE BIOLOGY OF STRESS

Intestinal Microbiota‐Generated Metabolite Trimethylamine‐N‐Oxide and 5‐Year Mortality Risk in Stable Coronary Artery Disease: The Contributory Role of Intestinal Microbiota in a COURAGE‐Like Patient Cohort

(2016) Vichai Senthong et al.   Journal of the American Heart Association

Trimethylamine N ‐Oxide and Mortality Risk in Patients With Peripheral Artery Disease

(2016) Vichai Senthong et al.   Journal of the American Heart Association

Gut Dysbiosis Is Linked to HypertensionNovelty and Significance

(2015) Tao Yang et al.   HYPERTENSION

Intestinal Microbiota Composition Modulates Choline Bioavailability from Diet and Accumulation of the Proatherogenic Metabolite Trimethylamine- N -Oxide

(2015) Kymberleigh A. Romano et al.   mBio

Trimethylamine-N-Oxide: A Carnitine-Derived Metabolite That Prolongs the Hypertensive Effect of Angiotensin II in Rats

(2014) Marcin Ufnal et al.   CANADIAN JOURNAL OF CARDIOLOGY

Plasma Choline Metabolites and Colorectal Cancer Risk in the Women's Health Initiative Observational Study

(2014) S. Bae et al.   CANCER RESEARCH

The Cardiovascular Effect of the Uremic Solute Indole-3 Acetic Acid

(2014) L. Dou et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Renin-Angiotensin-Aldosterone System Inhibition

(2014) Kelly Mercier et al.   PRIMARY CARE

Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis

(2013) Robert A Koeth et al.   NATURE MEDICINE

Microbial conversion of choline to trimethylamine requires a glycyl radical enzyme

(2012) S. Craciun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Does indoxyl sulfate, a uraemic toxin, have direct effects on cardiac fibroblasts and myocytes?

(2010) S. Lekawanvijit et al.   EUROPEAN HEART JOURNAL

QIIME allows analysis of high-throughput community sequencing data

(2010) J Gregory Caporaso et al.   NATURE METHODS

Serum Indoxyl Sulfate Is Associated with Vascular Disease and Mortality in Chronic Kidney Disease Patients

(2009) F. C. Barreto et al.   Clinical Journal of the American Society of Nephrology

Preoperative Angiotensin-Converting Enzyme Inhibitors and Acute Kidney Injury After Coronary Artery Bypass Grafting

(2008) Umberto Benedetto et al.   ANNALS OF THORACIC SURGERY