Inhibition of FOXO1 transcription factor in primary human adipocytes mimics the insulin-resistant state of type 2 diabetes
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Title
Inhibition of FOXO1 transcription factor in primary human adipocytes mimics the insulin-resistant state of type 2 diabetes
Authors
Keywords
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Journal
BIOCHEMICAL JOURNAL
Volume 475, Issue 10, Pages 1807-1820
Publisher
Portland Press Ltd.
Online
2018-05-04
DOI
10.1042/bcj20180144
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Related references
Note: Only part of the references are listed.- Systems-wide Experimental and Modeling Analysis of Insulin Signaling through Forkhead Box Protein O1 (FOXO1) in Human Adipocytes, Normally and in Type 2 Diabetes
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- Targeting FoxO1 with AS1842856 Suppresses Adipogenesis
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- A Single Mechanism Can Explain Network-wide Insulin Resistance in Adipocytes from Obese Patients with Type 2 Diabetes
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- Increased Adipogenesis of Human Adipose-Derived Stem Cells on Polycaprolactone Fiber Matrices
- (2014) Cecilia Brännmark et al. PLoS One
- Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors
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- Phosphorylation of IRS1 at Serine 307 in Response to Insulin in Human Adipocytes Is Not Likely to be Catalyzed by p70 Ribosomal S6 Kinase
- (2013) Meenu Rohini Rajan et al. PLoS One
- Mechanisms Regulating GLUT4 Transcription in Skeletal Muscle Cells Are Highly Conserved across Vertebrates
- (2013) Rubén Marín-Juez et al. PLoS One
- Novel repressor regulates insulin sensitivity through interaction with Foxo1
- (2012) Jun Nakae et al. EMBO JOURNAL
- mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes
- (2012) Maria J. Pereira et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- A Modified Protocol to Maximize Differentiation of Human Preadipocytes and Improve Metabolic Phenotypes
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- (2012) Thais Ortiz Hammes et al. Obesity Facts
- A Hierarchical Whole-body Modeling Approach Elucidates the Link betweenin VitroInsulin Signaling andin VivoGlucose Homeostasis
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- (2010) Cecilia Brännmark et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hepatic FoxO1 Ablation Exacerbates Lipid Abnormalities during Hyperglycemia
- (2010) Rebecca A. Haeusler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- FoxOs Function Synergistically to Promote Glucose Production
- (2010) Rebecca A. Haeusler et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- FOXO1 Transrepresses Peroxisome Proliferator-activated Receptor γ Transactivation, Coordinating an Insulin-induced Feed-forward Response in Adipocytes
- (2009) WuQiang Fan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Density functional computational studies on (E)-2-[(2-Hydroxy-5-nitrophenyl)-iminiomethyl]-4-nitrophenolate
- (2009) Hasan Tanak et al. JOURNAL OF MOLECULAR MODELING
- Unknown
- (2009) Anna Danielsson et al. MOLECULAR MEDICINE
- Inactivation of Hepatic Foxo1 by Insulin Signaling Is Required for Adaptive Nutrient Homeostasis and Endocrine Growth Regulation
- (2008) Xiaocheng C. Dong et al. Cell Metabolism
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