Inhibition of FOXO1 transcription factor in primary human adipocytes mimics the insulin-resistant state of type 2 diabetes

Systems-wide Experimental and Modeling Analysis of Insulin Signaling through Forkhead Box Protein O1 (FOXO1) in Human Adipocytes, Normally and in Type 2 Diabetes

(2016) Meenu Rohini Rajan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Targeting FoxO1 with AS1842856 Suppresses Adipogenesis

(2014) Peng Zou et al.   CELL CYCLE

A Single Mechanism Can Explain Network-wide Insulin Resistance in Adipocytes from Obese Patients with Type 2 Diabetes

(2014) Elin Nyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Increased Adipogenesis of Human Adipose-Derived Stem Cells on Polycaprolactone Fiber Matrices

(2014) Cecilia Brännmark et al.   PLoS One

Integrated control of hepatic lipogenesis versus glucose production requires FoxO transcription factors

(2014) Rebecca A. Haeusler et al.   Nature Communications

FOXO1 inhibition yields functional insulin-producing cells in human gut organoid cultures

(2014) Ryotaro Bouchi et al.   Nature Communications

Insulin Signaling in Type 2 Diabetes

(2013) Cecilia Brännmark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphorylation of IRS1 at Serine 307 in Response to Insulin in Human Adipocytes Is Not Likely to be Catalyzed by p70 Ribosomal S6 Kinase

(2013) Meenu Rohini Rajan et al.   PLoS One

Mechanisms Regulating GLUT4 Transcription in Skeletal Muscle Cells Are Highly Conserved across Vertebrates

(2013) Rubén Marín-Juez et al.   PLoS One

Novel repressor regulates insulin sensitivity through interaction with Foxo1

(2012) Jun Nakae et al.   EMBO JOURNAL

mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes

(2012) Maria J. Pereira et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

A Modified Protocol to Maximize Differentiation of Human Preadipocytes and Improve Metabolic Phenotypes

(2012) Mi-Jeong Lee et al.   Obesity

Parallel Down-Regulation of FOXO1, PPAR? and Adiponectin mRNA Expression in Visceral Adipose Tissue of Class III Obese Individuals

(2012) Thais Ortiz Hammes et al.   Obesity Facts

A Hierarchical Whole-body Modeling Approach Elucidates the Link betweenin VitroInsulin Signaling andin VivoGlucose Homeostasis

(2011) Elin Nyman et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mass and Information Feedbacks through Receptor Endocytosis Govern Insulin Signaling as Revealed Using a Parameter-free Modeling Framework

(2010) Cecilia Brännmark et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hepatic FoxO1 Ablation Exacerbates Lipid Abnormalities during Hyperglycemia

(2010) Rebecca A. Haeusler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FoxOs Function Synergistically to Promote Glucose Production

(2010) Rebecca A. Haeusler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

FOXO1 Transrepresses Peroxisome Proliferator-activated Receptor γ Transactivation, Coordinating an Insulin-induced Feed-forward Response in Adipocytes

(2009) WuQiang Fan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Density functional computational studies on (E)-2-[(2-Hydroxy-5-nitrophenyl)-iminiomethyl]-4-nitrophenolate

(2009) Hasan Tanak et al.   JOURNAL OF MOLECULAR MODELING

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(2009) Anna Danielsson et al.   MOLECULAR MEDICINE

Inactivation of Hepatic Foxo1 by Insulin Signaling Is Required for Adaptive Nutrient Homeostasis and Endocrine Growth Regulation

(2008) Xiaocheng C. Dong et al.   Cell Metabolism