Article
Chemistry, Physical
Jialong Shen, Yue Yuan, Sonja Salmon
Summary: This study presents a high-performance CO2 capture technology using textile structured packings with covalently immobilized carbonic anhydrase (CA) as catalysts. The results show that these packings have excellent CO2 absorption efficiency in various conditions, demonstrating their durability and stability.
Article
Biotechnology & Applied Microbiology
S. Fabbricino, S. Del Prete, M. E. Russo, C. Capasso, A. Marzocchella, P. Salatino
Summary: The study focuses on using a thermostable CA-based biocatalyst for CO2 absorption, with results showing the positive impact of reusability and equilibration with alkaline buffer on the performance of the catalyst. Further studies on optimizing enzyme loading and handling in CO2 absorption reactors are encouraged.
JOURNAL OF BIOTECHNOLOGY
(2021)
Article
Chemistry, Multidisciplinary
Jialong Shen, Yue Yuan, Sonja Salmon
Summary: In this study, high efficiency biocatalytic textile-based gas-liquid contactors were designed, fabricated, and tested for CO2 capture. The immobilized carbonic anhydrase (CA) enzyme accelerated CO2 absorption into benign, low-energy solvents, offering new possibilities for CO2 capture and direct air capture with high efficiency and longevity.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2022)
Article
Engineering, Chemical
Kaven Nguyen, Ion Iliuta, Francis Bougie, Louis-Cesar Pasquier, Maria C. Iliuta
Summary: A novel enzymatic CO2 capture process was evaluated and found to significantly reduce energy consumption, capital cost, and operating expenses compared to the benchmark MEA process. This technology is green, energy-efficient, non-toxic, and low-cost, showing promise for industrial applications.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Engineering, Chemical
Hannaneh Rasouli, Ion Iliuta, Francis Bougie, Alain Garnier, Maria C. Iliuta
Summary: A hybrid enzymatic CO2 absorption process using immobilized enzymes on a membrane and dispersed in a liquid phase was proposed. This process can achieve high absorption rates even if one component of the enzymatic system does not work properly.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Review
Environmental Sciences
Xing Zhu, Chenxi Du, Bo Gao, Bin He
Summary: High carbon dioxide concentration in the atmosphere calls for eco-friendly mitigation strategies. Carbonic anhydrase (CA) immobilization can enhance its stability and enzyme recycling, but there is limited mass transfer between gaseous CO2 and the active center of immobilized CA. This review focuses on improving the mass transfer process to increase the efficiency of enzymatic CO2 capture for industrial applications.
JOURNAL OF ENVIRONMENTAL MANAGEMENT
(2023)
Article
Engineering, Environmental
Ion Iliuta, Hannaneh Rasouli, Maria C. Iliuta
Summary: This study proposes an intensified CO2 capture method using an immobilized enzyme in a packed-bed microreactor. Experimental and theoretical analysis shows that the microreactor enhances mass transfer and improves CO2 conversion. Low enzyme loadings and specific buffer conditions favor CO2 capture. The performance of the microreactor surpasses that of traditional fixed-bed reactors and is suitable for green CO2 capture in various sectors.
CHEMICAL ENGINEERING JOURNAL
(2023)
Article
Engineering, Environmental
Hannaneh Rasouli, Ion Iliuta, Francis Bougie, Alain Garnier, Maria C. Iliuta
Summary: A novel enzymatic process using immobilized enzyme and magnetic nanoparticles in a packed-bed column bioreactor has been proposed to enhance CO2 absorption performance. The results demonstrated that the immobilized enzyme on the packing surface and magnetic nanoparticles exhibited high storage stability and could overcome the diffusion limitation of the enzyme on the packing surface. Overall, this technology design shows great potential for application.
CHEMICAL ENGINEERING JOURNAL
(2022)
Review
Biotechnology & Applied Microbiology
Maria Elena Russo, Clemente Capasso, Antonio Marzocchella, Piero Salatino
Summary: Carbonic anhydrase (CA) is a promising biocatalyst for the capture and utilization of CO2. Efficient immobilization methods have made it increasingly attractive for continuous bioreactors and industrial applications. This mini-review discusses various CA immobilization techniques and their advantages and disadvantages in CO2 capture and utilization processes. It also highlights the criteria for selecting the optimal CA-biocatalyst and designing CO2 absorption units, as well as presents potential applications of CA in enzymatic CO2 absorption processes.
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
(2022)
Article
Engineering, Chemical
Ion Iliuta, Hannaneh Rasouli, Maria C. Iliuta
Summary: An intensified enzymatic CO2 capture process was studied in a wall-coated enzyme-immobilized microreactor. The flow and mass transfer were improved to enhance the absorption rate of CO2. It was found that low enzyme concentrations, buffers with higher pKa2 constant, and higher buffer concentrations can improve enzymatic activity and stimulate the absorption process.
SEPARATION AND PURIFICATION TECHNOLOGY
(2023)
Article
Engineering, Environmental
Hannaneh Rasouli, Ion Iliuta, Francis Bougie, Alain Garnier, Maria C. Iliuta
Summary: The development of a biocatalytic flat sheet membrane for CO2 capture in membrane contactors shows promising performance and stability in industrial applications, highlighting its potential as an environmentally friendly approach in the field.
CHEMICAL ENGINEERING JOURNAL
(2021)
Article
Polymer Science
Jialong Shen, Sen Zhang, Xiaomeng Fang, Sonja Salmon
Summary: This study demonstrates the feasibility of using rapid UV-crosslinking to form interpenetrating polymer network hydrogels for enzyme immobilization and CO2 capture applications. The IPNH filaments and grids exhibited good mechanical properties and were suitable for further processing. The immobilized carbonic anhydrase showed high activity retention and long-term performance stability. This system has potential applications in 3D printing inks and biocatalytic reactors.
Article
Engineering, Chemical
Min Xiao, Jesse Thompson, Jialong Shen, Sonja Salmon, Kunlei Liu
Summary: Immobilizing carbonic anhydrase (CA) in textile structured packing (CATSP-2) modules improves CO2 separation performance and increases CO2 loading in the rich solvent, while maintaining good CA activity. The use of CATSP-2 could potentially reduce packing height and absorber column size, resulting in a lower cost per amount of CO2 captured.
Article
Engineering, Chemical
Bin Liu, Zhe Cui, Wende Tian
Summary: Tertiary amines are used as alternative absorbents for carbon capture, but their slow absorption rate increases costs and limits large-scale application. Carbonic anhydrase as a homogeneous catalyst can accelerate CO2 absorption in aqueous tertiary amines, significantly improving the reaction rate.
Review
Engineering, Chemical
Hannaneh Rasouli, Kaven Nguyen, Maria C. Iliuta
Summary: Currently, immobilization of the enzyme carbonic anhydrase (CA) is considered a promising approach to enhance the activity, stability, and reusability of CA for CO2 capture. Different immobilization strategies and supports have been developed to improve the performance and efficiency of large-scale applications. This state-of-the-art review analyzes the scientific literature on immobilization of CA and carbon capture technologies using immobilized CA, highlighting the benefits, issues, and limitations. Modelling approaches and techno-economic analyses are also presented to assess the feasibility of enzymatic capture processes in an industrial context.
SEPARATION AND PURIFICATION TECHNOLOGY
(2022)
Article
Chemistry, Medicinal
Francesca Mancuso, Andrea Angeli, Viviana De Luca, Federica Bucolo, Laura De Luca, Clemente Capasso, Claudiu T. Supuran, Rosaria Gitto
Summary: This study reports on the screening process of inhibitors targeting carbonic anhydrases expressed in bacteria. By studying the inhibitory effects and selectivity of newly synthesized analogs, it was found that simple structural modifications can have a significant impact on inhibition and selectivity. Although the best active inhibitors showed high activity against bacterial carbonic anhydrases, they demonstrated a loss of selectivity towards human isozymes, highlighting the need for further development of more promising inhibitors.
ARCHIV DER PHARMAZIE
(2022)
Article
Biochemistry & Molecular Biology
Giulia Nannini, Viviana De Luca, Chiara D'Ambrosio, Andrea Scaloni, Antonio Taddei, Maria Novella Ringressi, Fabio Cianchi, Fabio Staderini, Clemente Capasso, Amedeo Amedei, Claudiu T. Supuran
Summary: This study investigated the expression of carbonic anhydrase isoforms in tumour-infiltrating lymphocytes (TILs) in colorectal cancer. The results showed that T lymphocytes isolated from healthy surrounding mucosa had higher carbonic anhydrase activity compared to those in tumour and peripheral blood in the same patients, suggesting a dysregulation of the local immune response and a loss of effective anticancer mechanisms mediated by carbonic anhydrase in CRC tissues.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
(2022)
Article
Engineering, Chemical
Piero Salatino, Roberto Chirone, Roland Clift
Summary: Climate change and resource scarcity require radical socio-economic change for sustainability. Chemical engineering provides a unique skill-set that can contribute to this transition by offering a system-level understanding of economic activities from the perspective of industrial ecology.
CANADIAN JOURNAL OF CHEMICAL ENGINEERING
(2023)
Article
Engineering, Chemical
Maurizio Troiano, Valeria Ianzito, Roberto Solimene, Elvis Tinashe Ganda, Piero Salatino
Summary: A one-dimensional model of a fluidized bed pyrolytic converter for biomass is presented in this paper. The fate of biomass and resulting char is modelled by considering elutriation, attrition, and bed drain/regeneration. The study focuses on the role of heterogeneous volatile-char secondary reactions and their importance in controlling char loading in the bed. The results highlight the significance of these reactions in reactor performance and provide guidelines for optimal design and control of fluidized bed pyrolyzers.
CANADIAN JOURNAL OF CHEMICAL ENGINEERING
(2023)
Article
Chemistry, Medicinal
Morteza Abdoli, Viviana De Luca, Clemente Capasso, Claudiu T. T. Supuran, Raivis Zalubovskis
Summary: Two novel sulfaguanidine series were synthesized by desulfidative amination of dimethyl arylsulfonylcarbonimidodithioates. These compounds were tested for their inhibition of human carbonic anhydrase isozymes. The N-(N-alkyl/benzyl-carbamimidoyl) benzenesulfonamide derivatives showed higher inhibitory activity than the N-(N,N'-dialkyl/dibenzyl-carbamimidoyl) benzenesulfonamide derivatives.
Article
Biochemistry & Molecular Biology
Andrea Angeli, Anthi Petrou, Victor Kartsev, Boris Lichitsky, Andrey Komogortsev, Clemente Capasso, Athina Geronikaki, Claudiu T. Supuran
Summary: Carbonic anhydrases play a crucial role in the CO2 hydration reaction in all living organisms and have potential as antiinfective targets. Griseofulvin and usnic acid sulfonamides were synthesized and evaluated as potential CA inhibitors. These compounds showed interesting inhibitory activity against various isoforms of CA, as well as a fungal enzyme. Computational studies were performed to understand the binding mode of these compounds in the active site of human CAs.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Simone Giovannuzzi, Viviana De Luca, Clemente Capasso, Claudiu T. Supuran
Summary: The gamma-carbonic anhydrase (CA, EC 4.2.1.1) from Mammaliicoccus (Staphylococcus) sciuri (MscCA gamma) was studied for its inhibition by various (in)organic anions. Peroxydisulfate and trithiocarbonate were the most effective inhibitors, while other anions showed weaker inhibitory effects. Finding more effective MscCA gamma inhibitors could help combat antibiotic resistance.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
(2023)
Article
Biochemistry & Molecular Biology
Morteza Abdoli, Viviana De Luca, Clemente Capasso, Claudiu T. T. Supuran, Raivis Zalubovskis
Summary: A library of novel thiazolone-benzenesulphonamides was synthesized and evaluated for their inhibitory activity against human cytosolic carbonic anhydrases and bacterial carbonic anhydrases. The prepared compounds 4a-4j showed low nanomolar range inhibition against all investigated hCAs. Compound 4d exhibited strong inhibition against bacterial MscCA beta with a K-I of 73.6 nM, much better than AAZ. The tested compounds showed medium inhibitory potency against StCA1 compared to the standard drug, while poorly inhibited StCA2.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
(2023)
Review
Infectious Diseases
Alessio Nocentini, Clemente Capasso, Claudiu T. Supuran
Summary: Resistance to antibiotic treatment occurs when microorganisms resist clinically approved antibiotics. Medication repurposing/repositioning is a strategy that can help find new antibiotics. Among them, Zn2+ ion binders, such as sulfonamides and their bioisosteres, are considered promising compounds for obtaining novel antibacterials.
Review
Chemistry, Medicinal
Clemente Capasso, Claudiu T. Supuran
Summary: This article discusses 12 protozoan genera that cause zoonotic diseases in humans and animals, with a focus on Babesia spp and Entamoeba histolytica, and mentions Toxoplasma gondii, Trypanosoma cruzi, and Leishmania spp. Despite a deep understanding of the complex life cycles of pathogenic protozoa, this has not led to the discovery of new drugs. The current clinical armamentarium for treating protozoan diseases is limited and often ineffective, necessitating innovative approaches to address these challenges.
EXPERT OPINION ON THERAPEUTIC PATENTS
(2023)
Article
Chemistry, Medicinal
Morteza Abdoli, Viviana De Luca, Clemente Capasso, Claudiu T. Supuran, Raivis Zalubovskis
Summary: This study identifies novel sulfonamide-based compounds as selective inhibitors of hCA IX and XII, suggesting their potential for cancer treatment.
FUTURE MEDICINAL CHEMISTRY
(2023)
Editorial Material
Biochemistry & Molecular Biology
Clemente Capasso
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Valentina Puca, Gabriele Turacchio, Beatrice Marinacci, Claudiu T. Supuran, Clemente Capasso, Pamela Di Giovanni, Ilaria D'Agostino, Simone Carradori, Rossella Grande
Summary: The World Health Organization has identified Helicobacter pylori as a high-priority pathogen requiring updated antibacterial treatments. This study investigated the potential of combining a CA inhibitor, carvacrol (CAR), amoxicillin (AMX), and a urease inhibitor (SHA) to develop a multiple-targeted anti-H. pylori therapy. The combinations of these compounds showed strong inhibition of H. pylori growth and biofilm formation, with CAR-AMX and CAR-SHA combinations demonstrating additive effects and AMX-SHA combination showing indifferent effects.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Simone Carradori, Andrea Angeli, Patrick S. Sfragano, Xheila Yzeiri, Massimo Calamante, Damiano Tanini, Antonella Capperucci, Hannah Kunstek, Mihayl Varbanov, Clemente Capasso, Claudiu T. Supuran
Summary: In this study, new heptamethine-based compounds decorated with a sulfonamide moiety were synthesized for selectively inhibiting bacterial carbonic anhydrases (CAs) and being photoactivated by specific wavelengths. The compounds showed potent CA inhibition and a slight preference for bacterial isoforms. They also exhibited promising effects against S. epidermidis under irradiation, while being non-cytotoxic to human red blood cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
(2023)
Article
Biochemistry & Molecular Biology
Marialuigia Fantacuzzi, Ilaria D'Agostino, Simone Carradori, Francesco Liguori, Fabrizio Carta, Mariangela Agamennone, Andrea Angeli, Filomena Sannio, Jean-Denis Docquier, Clemente Capasso, Claudiu T. Supuran
Summary: Vibrio cholerae, a pathogen responsible for life-threatening infections in low-income countries, has developed resistance to antibacterial drugs. Researchers have identified carbonic anhydrases (CAs) encoded by V. cholerae as potential pharmacological targets. They have developed a large library of CAs inhibitors with different flexibility degrees and found compounds with strong inhibition against Vch alpha CA. Computational studies have provided insights into the inhibitory activity and isoform selectivity of these compounds.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY
(2023)
Article
Biotechnology & Applied Microbiology
Yiran Qu, Innocent Bekard, Ben Hunt, Jamie Black, Louis Fabri, Sally L. Gras, Sandra. E. Kentish
Summary: This study compares the performance of a nanofiber device and a resin column for antibody capture. The nanofiber device has a larger housing volume and lower binding capacity, but comparable eluate purity to the resin column. It shows high stability, can be used for multiple cycles, and maintains consistent eluate quality when scaled up. The use of a single nanofiber device can significantly reduce costs compared to a resin column, especially when the number of batches is limited.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Brandon Moore, Christos Georgakis, Chris Antoniou, Sarwat Khattak
Summary: Fed-batch cell culture processes are commonly used in biomanufacturing due to their simplicity and applicability in cGMP environments. However, the challenge lies in the changing physiochemical conditions within the bioreactor as the cell density changes. Traditional response surface models (RSMs) are commonly used for optimization but are limited by their use of time-invariant factors. Dynamic RSM (DRSM) models can predict the time-dependent impact of process inputs, allowing for optimization of process operations that change over time.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Lin Li, Yunfan Bai, Chuhua Qi, Yile Du, Xiaoxiao Ma, Yutong Li, Pingping Wu, Shuangli Chen, Sijing Zhang
Summary: A succinic anhydride-modified apple pomace (SAMAP) was synthesized to address environmental issues caused by the accumulation of apple pomace and effectively treat heavy metal ions. SAMAP exhibited high adsorption capacity for Cu(II) and Pb(II), suggesting its potential application in wastewater treatment.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Peter Satzer
Summary: Water for injection (WFI) production in the biopharmaceutical industry consumes excessive amounts of water and energy. Recycling buffers can potentially save up to 90% of resources, but achieving the full theoretical potential is impossible when a risk-aware design is used. Universal risk-based assessment is important for regulatory authorities to consider the implementation of such a strategy.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Gaoya Sun, Lingkai Jin, Guangxue Wang, Xiaoge Wang, Jin Huang
Summary: In this study, heterologous expression and homologous overexpression of ABC transporter proteins AatA and MdlB were found to improve butyric acid production in C. tyrobutyricum. The overexpression of these proteins upregulated the expression levels of key enzymes in the acetate synthesis pathway and promoted the synthesis and secretion of acetic acid. Additionally, the increase in ATPase activity facilitated sugar utilization, induced extracellular secretion of acetate, and shortened fermentation periods.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Taiki Okamura, Rina Aritomi, Takuya Matsumoto, Ryosuke Yamada, Hidehiko Hirakawa, Hiroyasu Ogino
Summary: In this study, proline was introduced to improve the stability of putidaredoxin reductase (PdR) in the Pseudomonas putida cytochrome P450 system. It was found that PdR_T221P had a longer half-life at high temperatures compared to wild-type PdR, but a shorter half-life in the presence of methanol. Molecular dynamics simulations supported these findings.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Yuying Hu, Xiaofan Wang, Shihao Zhang, Zimu Liu, Tengfang Hu, Xin Wang, Xiaoming Peng, Hongling Dai, Jing Wu, Fengping Hu
Summary: This study investigates the effect of iron-carbon micro-electrolysis (ICME) materials on high-solid anaerobic digestion (HSAD). The results show that ICME materials promote methane production in HSAD by increasing the attachment area of microorganisms and facilitating symbiotic metabolism of certain bacterial species. This study provides new insights into microbial mechanisms and enhances our understanding of ICME material enhancement in HSAD.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Jibao Liu, Yufeng Xu, Yuansong Wei
Summary: This study investigated the role of sludge rheology in anaerobic digestion (AD) and found that rheological properties increased with the increase of solid content, resulting in a negative effect on methane production. An extended ADM1 model revealed that enhanced sludge rheological properties increased mass diffusion resistance and reduced uptake rate of acetate.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Xiaoyan Liu, Zongze Chen, Dewen Kong, Xinying Zhang, Chuanhua Wang, Yongqi Wang
Summary: This study explored the role of intracellular and extracellular enzymes of Acinetobacter baumannii and Talaromyces sp. in the degradation of crude oil. The extracellular enzymes of Talaromyces sp. were more effective in degrading n-alkanes, while those of Acinetobacter baumannii had a better effect on aromatic hydrocarbons. The degradation enzyme systems of both bacteria and fungi complemented each other, improving the overall degradation ability.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Jing Dong, Lingli Xu, Yuxiang Liu, Li Ren, Ke Yuan
Summary: The utilization of biochar-immobilized microorganisms is an effective method for eliminating phenol from water. The high susceptibility of bacteria to environmental factors is a challenge for practical implementation. In this study, biochar was used to reduce microbial susceptibility and enhance phenol removal. The addition of biochar altered the dominant species of phenol-degrading bacteria and response surface analysis indicated the significant influence of biochar pyrolysis temperature and experimental temperature on phenol removal rate.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Zibin Pan, Mengying Liu, Zuliang Chen
Summary: This study successfully removed metalloids and heavy metals from acid mine drainage (AMD) using bio-synthesized Fe/Cu nanoparticles (Fe/Cu NPs). The Fe/Cu NPs showed high removal capacities and the presence of organic substances contributed to their stability.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Guangbing Liu, Han Zhang, Jincan Huang, Lu Zhang, Teng Zhang, Xuemin Yu, Weijing Liu, Chunkai Huang
Summary: This study investigated the effect of Fenton pre-treatment on the treatment efficiency of printing and dyeing wastewater (PDW) using two anaerobic/aerobic-membrane bioreactors (A/O-MBRs). The results showed that Fenton pre-treatment significantly improved the removal efficiency of COD and AOX in PDW, and reduced membrane fouling. The Shannon indices and metagenomics analysis indicated that the microbial diversity in anaerobic flocs was higher than that in aerobic flocs, and EC3.1.1.45 and pcaI were identified as key functional genes.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Lidia Borgosz, Duygu Dikicioglu
Summary: The Industrial Internet of Things (IIoT) is a system that connects devices and provides real-time insight into industrial processes. However, the complexity and regulatory requirements of the biomanufacturing sector make it challenging to implement IIoT. There is a need for universal solutions to overcome this challenge and advance the field of biomanufacturing.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Yajie Li, Weikang Kong, Yuyao Zhang, Huarui Zhou, Hongbo Liu, Salma Tabassum
Summary: In this study, the iron-carbon multi-micro electric field coupling anaerobic co-digestion technique was used to treat coal gasification wastewater (CGW). The experimental results showed that under optimal operating conditions, this technique can significantly reduce the toxicity of the wastewater and achieve high removal efficiencies. Additionally, the analysis of microbial communities revealed that the coupling system promotes direct interspecies electron transfer.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)
Article
Biotechnology & Applied Microbiology
Aparecido Nivaldo Modenes, Debora Gozzi Fernandes, Daniela Estelita Goes Trigueros, Matheus Guilherme Amador, Fernando Rodolfo Espinoza-Quinones, Taysa de Souza Braniz, Adilson Ricken Schuelter, Glacy Jaqueline da Silva, Lucimar Pereira Bonett
Summary: This study aimed to systematically remove organic pollutants from raw dairy wastewater with high concentrations of COD, TOC, and TN using Poterioochromonas malhamensis algae strains. The results showed that the biomass yield rate using FP-PBRs was 10% higher than tubular PBRs, and the organic pollution in wastewater was significantly reduced with a decrease of about 98% in COD, 95% in TN, and 92% in TOC.
BIOCHEMICAL ENGINEERING JOURNAL
(2024)