Extending Causality Tests with Genetic Instruments: An Integration of Mendelian Randomization with the Classical Twin Design

Sensitivity Analyses for Robust Causal Inference from Mendelian Randomization Analyses with Multiple Genetic Variants

(2017) Stephen Burgess et al.   EPIDEMIOLOGY

Consistent Estimation in Mendelian Randomization with Some Invalid Instruments Using a Weighted Median Estimator

(2016) Jack Bowden et al.   GENETIC EPIDEMIOLOGY

A plethora of pleiotropy across complex traits

(2016) Peter M Visscher et al.   NATURE GENETICS

Detection and interpretation of shared genetic influences on 42 human traits

(2016) Joseph K Pickrell et al.   NATURE GENETICS

Mendelian Randomization: New Applications in the Coming Age of Hypothesis-Free Causality

(2015) David M. Evans et al.   Annual Review of Genomics and Human Genetics

Mendelian randomization with invalid instruments: effect estimation and bias detection through Egger regression

(2015) J. Bowden et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Effect of Naturally Random Allocation to Lower Low-Density Lipoprotein Cholesterol on the Risk of Coronary Heart Disease Mediated by Polymorphisms in NPC1L1, HMGCR, or Both

(2015) Brian A. Ference et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

OpenMx 2.0: Extended Structural Equation and Statistical Modeling

(2015) Michael C. Neale et al.   PSYCHOMETRIKA

Causal Effects of Body Mass Index on Cardiometabolic Traits and Events: A Mendelian Randomization Analysis

(2014) Michael V. Holmes et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Using Multivariable Mendelian Randomization to Disentangle the Causal Effects of Lipid Fractions

(2014) Stephen Burgess et al.   PLoS One

The many weak instruments problem and Mendelian randomization

(2014) Neil M. Davies et al.   STATISTICS IN MEDICINE

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data

(2014) M. V. Holmes et al.   BMJ-British Medical Journal

Genetic Predisposition to Increased Blood Cholesterol and Triglyceride Lipid Levels and Risk of Alzheimer Disease: A Mendelian Randomization Analysis

(2014) Petroula Proitsi et al.   PLOS MEDICINE

Genetic risk score analysis indicates migraine with and without comorbid depression are genetically different disorders

(2013) Lannie Ligthart et al.   HUMAN GENETICS

Calculating statistical power in Mendelian randomization studies

(2013) Marie-Jo A Brion et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Use of allele scores as instrumental variables for Mendelian randomization

(2013) Stephen Burgess et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Pleiotropy in complex traits: challenges and strategies

(2013) Nadia Solovieff et al.   NATURE REVIEWS GENETICS

The NHGRI GWAS Catalog, a curated resource of SNP-trait associations

(2013) Danielle Welter et al.   NUCLEIC ACIDS RESEARCH

Twin Registries Worldwide: An Important Resource for Scientific Research

(2013) Yoon-Mi Hur et al.   Twin Research and Human Genetics

The Finnish Twin Cohort Study: An Update

(2013) Jaakko Kaprio   Twin Research and Human Genetics

The Adult Netherlands Twin Register: Twenty-Five Years of Survey and Biological Data Collection

(2013) Gonneke Willemsen et al.   Twin Research and Human Genetics

Mining the Human Phenome Using Allelic Scores That Index Biological Intermediates

(2013) David M. Evans et al.   PLoS Genetics

Causal Relationship between Obesity and Vitamin D Status: Bi-Directional Mendelian Randomization Analysis of Multiple Cohorts

(2013) Karani S. Vimaleswaran et al.   PLOS MEDICINE

Five Years of GWAS Discovery

(2012) Peter M. Visscher et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Effect of Long-Term Exposure to Lower Low-Density Lipoprotein Cholesterol Beginning Early in Life on the Risk of Coronary Heart Disease

(2012) Brian A. Ference et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Causes of Comorbidity: Pleiotropy or Causality? Shared Genetic and Environmental Influences on Migraine and Neuroticism

(2012) Lannie Ligthart et al.   Twin Research and Human Genetics

The Danish Twin Registry: Linking Surveys, National Registers, and Biological Information

(2012) Axel Skytthe et al.   Twin Research and Human Genetics

The Young Netherlands Twin Register (YNTR): Longitudinal Twin and Family Studies in Over 70,000 Children

(2012) Catharina E. M. van Beijsterveldt et al.   Twin Research and Human Genetics

Abundant Pleiotropy in Human Complex Diseases and Traits

(2011) Shanya Sivakumaran et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Avoiding bias from weak instruments in Mendelian randomization studies

(2011) Stephen Burgess et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Using multiple genetic variants as instrumental variables for modifiable risk factors

(2011) Tom M Palmer et al.   STATISTICAL METHODS IN MEDICAL RESEARCH

Use of genetic markers and gene-diet interactions for interrogating population-level causal influences of diet on health

(2010) George Davey Smith   Genes and Nutrition

Power and instrument strength requirements for Mendelian randomization studies using multiple genetic variants

(2010) Brandon L Pierce et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Are Extended Twin Family Designs Worth the Trouble? A Comparison of the Bias, Precision, and Accuracy of Parameters Estimated in Four Twin Family Models

(2009) Matthew C. Keller et al.   BEHAVIOR GENETICS

Harnessing the information contained within genome-wide association studies to improve individual prediction of complex disease risk

(2009) David M. Evans et al.   HUMAN MOLECULAR GENETICS

Testing Causality in the Association Between Regular Exercise and Symptoms of Anxiety and Depression

(2008) Marleen H. M. De Moor et al.   ARCHIVES OF GENERAL PSYCHIATRY

Mendelian Randomisation and Causal Inference in Observational Epidemiology

(2008) Nuala A Sheehan et al.   PLOS MEDICINE