A ubiquitin-binding CUE domain in presenilin-1 enables interaction with K63-linked polyubiquitin chains

The γ-secretase complex: from structure to function

(2014) Xian Zhang et al.   Frontiers in Cellular Neuroscience

Involvement of presenilin holoprotein upregulation in calcium dyshomeostasis of Alzheimer's disease

(2013) Kamran Honarnejad et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

Presenilins: Role in calcium homeostasis

(2012) Kamran Honarnejad et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

The dysregulation of intracellular calcium in Alzheimer disease

(2010) Charlene Supnet et al.   CELL CALCIUM

Presenilin and γ -Secretase Activity: A Viable Therapeutic Target for Alzheimers Disease?

(2010) Run Yan et al.   Current Signal Transduction Therapy

Ubiquitin Regulates GGA3-mediated Degradation of BACE1

(2010) Eugene L. Kang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Presenilins in Neuronal Calcium Homeostasis

(2010) H. Zhang et al.   JOURNAL OF NEUROSCIENCE

The Diversity of Ubiquitin Recognition: Hot Spots and Varied Specificity

(2010) Jason M. Winget et al.   MOLECULAR CELL

TRAF6 promotes ubiquitination and regulated intramembrane proteolysis of IL-1R1

(2009) Ciara Twomey et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The emerging complexity of protein ubiquitination

(2009) David Komander   BIOCHEMICAL SOCIETY TRANSACTIONS

Ubiquitin ligase complexes: from substrate selectivity to conjugational specificity

(2009) Vanja Nagy et al.   BIOLOGICAL CHEMISTRY

Presenilin-dependent regulated intramembrane proteolysis and γ-secretase activity

(2009) J. V. McCarthy et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Functional Roles of Ubiquitin-Like Domain (ULD) and Ubiquitin-Binding Domain (UBD) Containing Proteins

(2009) Caroline Grabbe et al.   CHEMICAL REVIEWS

Nonproteolytic Functions of Ubiquitin in Cell Signaling

(2009) Zhijian J. Chen et al.   MOLECULAR CELL

Ubiquitin linkages make a difference

(2009) Ivan Dikic et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Two-sided ubiquitin binding explains specificity of the TAB2 NZF domain

(2009) Yogesh Kulathu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Atypical ubiquitin chains: new molecular signals. ‘Protein Modifications: Beyond the Usual Suspects’ Review Series

(2008) Fumiyo Ikeda et al.   EMBO REPORTS

Interleukin-1 Receptor Type 1 Is a Substrate for γ-Secretase-dependent Regulated Intramembrane Proteolysis

(2008) Baukje M. Elzinga et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association between Presenilin-1 and TRAF6 modulates regulated intramembrane proteolysis of the p75NTRneurotrophin receptor

(2008) James C. Powell et al.   JOURNAL OF NEUROCHEMISTRY

The Jpred 3 secondary structure prediction server

(2008) C. Cole et al.   NUCLEIC ACIDS RESEARCH