Protease signaling in animal and plant-regulated cell death

The Paracaspase MALT1

(2016) Janna Hachmann et al.   BIOCHIMIE

Comparative structural analysis of the caspase family with other clan CD cysteine peptidases

(2015) Karen McLuskey et al.   BIOCHEMICAL JOURNAL

Substrate Specificity and Possible Heterologous Targets of Phytaspase, a Plant Cell Death Protease

(2015) Raisa A. Galiullina et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling

(2015) Nobuhiko Kayagaki et al.   NATURE

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Eaten alive: novel insights into autophagy from multicellular model systems

(2015) Hong Zhang et al.   TRENDS IN CELL BIOLOGY

Only in dying, life: programmed cell death during plant development

(2015) Tom Van Hautegem et al.   TRENDS IN PLANT SCIENCE

Design of a Selective Substrate and Activity Based Probe for Human Neutrophil Serine Protease 4

(2015) Paulina Kasperkiewicz et al.   PLoS One

The plant metacaspase AtMC1 in pathogen-triggered programmed cell death and aging: functional linkage with autophagy

(2014) N S Coll et al.   CELL DEATH AND DIFFERENTIATION

The death of plant cells: from proteases to field applications

(2014) S Stael et al.   CELL DEATH AND DIFFERENTIATION

Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

(2014) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Programmed Cell Death Controlled by ANAC033/SOMBRERO Determines Root Cap Organ Size in Arabidopsis

(2014) Matyáš Fendrych et al.   CURRENT BIOLOGY

Mutation of a Self-Processing Site in Caspase-8 Compromises Its Apoptotic but Not Its Nonapoptotic Functions in Bacterial Artificial Chromosome-Transgenic Mice

(2014) T.-B. Kang et al.   JOURNAL OF IMMUNOLOGY

Stat3 controls cell death during mammary gland involution by regulating uptake of milk fat globules and lysosomal membrane permeabilization

(2014) Timothy J. Sargeant et al.   NATURE CELL BIOLOGY

Regulated necrosis: the expanding network of non-apoptotic cell death pathways

(2014) Tom Vanden Berghe et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Caspase-2: the reinvented enzyme

(2014) M Olsson et al.   ONCOGENE

The Cysteine Protease CEP1, a Key Executor Involved in Tapetal Programmed Cell Death, Regulates Pollen Development inArabidopsis

(2014) Dandan Zhang et al.   PLANT CELL

Design of ultrasensitive probes for human neutrophil elastase through hybrid combinatorial substrate library profiling

(2014) P. Kasperkiewicz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Life-span extension by a metacaspase in the yeast Saccharomyces cerevisiae

(2014) S. M. Hill et al.   SCIENCE

Functions of caspase 8: The identified and the mysterious

(2014) Guy S. Salvesen et al.   SEMINARS IN IMMUNOLOGY

A Natural Genetic Variant of Granzyme B Confers Lethality to a Common Viral Infection

(2014) Christopher E. Andoniou et al.   PLoS Pathogens

Mouse granzyme A induces a novel death with writhing morphology that is mechanistically distinct from granzyme B-induced apoptosis

(2013) O Susanto et al.   CELL DEATH AND DIFFERENTIATION

Caspase-2 as a tumour suppressor

(2013) J Puccini et al.   CELL DEATH AND DIFFERENTIATION

Autophagy and metacaspase determine the mode of cell death in plants

(2013) Elena A. Minina et al.   JOURNAL OF CELL BIOLOGY

Caspase-2 at a glance

(2013) L. L. Fava et al.   JOURNAL OF CELL SCIENCE

Lysosomal cell death at a glance

(2013) S. Aits et al.   JOURNAL OF CELL SCIENCE

Antiinflammatory effects of apoptotic cells

(2013) Peter M. Henson et al.   JOURNAL OF CLINICAL INVESTIGATION

Post mortemfunction of AtMC9 in xylem vessel elements

(2013) Benjamin Bollhöner et al.   NEW PHYTOLOGIST

The Arabidopsis METACASPASE9 Degradome

(2013) L. Tsiatsiani et al.   PLANT CELL

Set-point control of RD21 protease activity by AtSerpin1 controls cell death in Arabidopsis

(2013) Nardy Lampl et al.   PLANT JOURNAL

Combined Inhibition of Autophagy and Caspases Fails to Prevent Developmental Nurse Cell Death in the Drosophila melanogaster Ovary

(2013) Jeanne S. Peterson et al.   PLoS One

The Endolysosomal System in Cell Death and Survival

(2013) U. Repnik et al.   Cold Spring Harbor Perspectives in Biology

Clearing the Dead: Apoptotic Cell Sensing, Recognition, Engulfment, and Digestion

(2013) A. Hochreiter-Hufford et al.   Cold Spring Harbor Perspectives in Biology

EAT1 promotes tapetal cell death by regulating aspartic proteases during male reproductive development in rice

(2013) Ningning Niu et al.   Nature Communications

Protective Roles for Caspase-8 and cFLIP in Adult Homeostasis

(2013) Ricardo Weinlich et al.   Cell Reports

A Bipartite Molecular Module Controls Cell Death Activation in the Basal Cell Lineage of Plant Embryos

(2013) Peng Zhao et al.   PLOS BIOLOGY

Cysteine cathepsins are not critical for TRAIL- and CD95-induced apoptosis in several human cancer cell lines

(2012) Aleš Špes et al.   BIOLOGICAL CHEMISTRY

The family of Deg/HtrA proteases in plants

(2012) Holger Schuhmann et al.   BMC PLANT BIOLOGY

Antagonic activities of Trypanosoma cruzi metacaspases affect the balance between cell proliferation, death and differentiation

(2012) M Laverrière et al.   CELL DEATH AND DIFFERENTIATION

Cathepsin D Primes Caspase-8 Activation by Multiple Intra-chain Proteolysis

(2012) Sébastien Conus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Requirements for NADPH oxidase and myeloperoxidase in neutrophil extracellular trap formation differ depending on the stimulus

(2012) Heather Parker et al.   JOURNAL OF LEUKOCYTE BIOLOGY

A Perspective on Mammalian Caspases as Positive and Negative Regulators of Inflammation

(2012) Seamus J. Martin et al.   MOLECULAR CELL

Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1

(2012) Petr Broz et al.   NATURE

The proteasome is responsible for caspase-3-like activity during xylem development

(2012) Jia-Jia Han et al.   PLANT JOURNAL

A Role in Immunity for Arabidopsis Cysteine Protease RD21, the Ortholog of the Tomato Immune Protease C14

(2012) Takayuki Shindo et al.   PLoS One

Mitochondrial pathway of apoptosis is ancestral in metazoans

(2012) C. E. Bender et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tricking the Guard: Exploiting Plant Defense for Disease Susceptibility

(2012) J. Lorang et al.   SCIENCE

Caspase Substrates and Cellular Remodeling

(2011) Emily D. Crawford et al.   Annual Review of Biochemistry

FLIPLinduces caspase 8 activity in the absence of interdomain caspase 8 cleavage and alters substrate specificity

(2011) Cristina Pop et al.   BIOCHEMICAL JOURNAL

Cysteine cathepsins: From structure, function and regulation to new frontiers

(2011) Vito Turk et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

A plant alternative to animal caspases: subtilisin-like proteases

(2011) A B Vartapetian et al.   CELL DEATH AND DIFFERENTIATION

Programmed cell death in the plant immune system

(2011) N S Coll et al.   CELL DEATH AND DIFFERENTIATION

Caspase-2: the orphan caspase

(2011) L Bouchier-Hayes et al.   CELL DEATH AND DIFFERENTIATION

Dying for a cause: NETosis, mechanisms behind an antimicrobial cell death modality

(2011) Q Remijsen et al.   CELL DEATH AND DIFFERENTIATION

Trypanosoma bruceiMetacaspase 4 Is a Pseudopeptidase and a Virulence Factor

(2011) William R. Proto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Classes of programmed cell death in plants, compared to those in animals

(2011) W. G. van Doorn   JOURNAL OF EXPERIMENTAL BOTANY

Catalytic activity of the caspase-8–FLIPL complex inhibits RIPK3-dependent necrosis

(2011) Andrew Oberst et al.   NATURE

Non-canonical inflammasome activation targets caspase-11

(2011) Nobuhiko Kayagaki et al.   NATURE

MYB80, a regulator of tapetal and pollen development, is functionally conserved in crops

(2011) Huy A. Phan et al.   PLANT MOLECULAR BIOLOGY

Enzymatically active single chain caspase-8 maintains T-cell survival during clonal expansion

(2010) S Leverrier et al.   CELL DEATH AND DIFFERENTIATION

Genetic control of necrosis—another type of programmed cell death

(2010) Kimberly McCall   CURRENT OPINION IN CELL BIOLOGY

Phytaspase, a relocalisable cell death promoting plant protease with caspase specificity

(2010) Nina V Chichkova et al.   EMBO JOURNAL

Neutrophil elastase and myeloperoxidase regulate the formation of neutrophil extracellular traps

(2010) Venizelos Papayannopoulos et al.   JOURNAL OF CELL BIOLOGY

Pannexin 1 channels mediate ‘find-me’ signal release and membrane permeability during apoptosis

(2010) Faraaz B. Chekeni et al.   NATURE

Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria

(2010) Edward A Miao et al.   NATURE IMMUNOLOGY

Emerging principles in protease-based drug discovery

(2010) Marcin Drag et al.   NATURE REVIEWS DRUG DISCOVERY

Metacaspase Yca1 is required for clearance of insoluble protein aggregates

(2010) R. E. C. Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MS-driven protease substrate degradomics

(2010) Francis Impens et al.   PROTEOMICS

Arabidopsis Type I Metacaspases Control Cell Death

(2010) N. S. Coll et al.   SCIENCE

Critical Role for Caspase-8 in Epidermal Growth Factor Signaling

(2009) D. Finlay et al.   CANCER RESEARCH

Autophagic Components Contribute to Hypersensitive Cell Death in Arabidopsis

(2009) Daniel Hofius et al.   CELL

The ubiquitin proteasome system and its involvement in cell death pathways

(2009) F Bernassola et al.   CELL DEATH AND DIFFERENTIATION

A novel membrane fusion-mediated plant immunity against bacterial pathogens

(2009) N. Hatsugai et al.   GENES & DEVELOPMENT

Mechanisms of interleukin-1β release

(2009) Claudia Eder   IMMUNOBIOLOGY

Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome

(2009) Jens F. Sundström et al.   NATURE CELL BIOLOGY

The inflammasome: a caspase-1-activation platform that regulates immune responses and disease pathogenesis

(2009) Luigi Franchi et al.   NATURE IMMUNOLOGY

The Death Effector Domains of Caspase-8 Induce Terminal Differentiation

(2009) Ainhoa Mielgo et al.   PLoS One

Non-apoptotic functions of caspase-8

(2008) Jonathan Maelfait et al.   BIOCHEMICAL PHARMACOLOGY

Global Mapping of the Topography and Magnitude of Proteolytic Events in Apoptosis

(2008) Melissa M. Dix et al.   CELL

Classification of cell death: recommendations of the Nomenclature Committee on Cell Death 2009

(2008) G Kroemer et al.   CELL DEATH AND DIFFERENTIATION

What happened to plant caspases?

(2008) Laurent Bonneau et al.   JOURNAL OF EXPERIMENTAL BOTANY

Caspase-8 is activated by cathepsin D initiating neutrophil apoptosis during the resolution of inflammation

(2008) Sébastien Conus et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The persisting challenge of selective and specific proteasome inhibition

(2008) Michael Groll et al.   JOURNAL OF PEPTIDE SCIENCE

Measuring elastase, proteinase 3 and cathepsin G activities at the surface of human neutrophils with fluorescence resonance energy transfer substrates

(2008) Brice Korkmaz et al.   Nature Protocols

Arabidopsis Protein Disulfide Isomerase-5 Inhibits Cysteine Proteases during Trafficking to Vacuoles before Programmed Cell Death of the Endothelium in Developing Seeds

(2008) C. Andeme Ondzighi et al.   PLANT CELL

Cysteine proteases XCP1 and XCP2 aid micro-autolysis within the intact central vacuole during xylogenesis in Arabidopsis roots

(2008) Utku Avci et al.   PLANT JOURNAL

A Non-Death Role of the Yeast Metacaspase: Yca1p Alters Cell Cycle Dynamics

(2008) Robin E. C. Lee et al.   PLoS One

Antigen-mediated T cell expansion regulated by parallel pathways of death

(2008) I. L. Ch'en et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FADD and caspase-8 control the outcome of autophagic signaling in proliferating T cells

(2008) B. D. Bell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA