Human α-defensins are immune-related Kv1.3 channel inhibitors: new support for their roles in adaptive immunity

Plectasin, First Animal Toxin-Like Fungal Defensin Blocking Potassium Channels through Recognizing Channel Pore Region

(2015) Fang Xiang et al.   Toxins

TCF-1-mediated Wnt signaling regulates Paneth cell innate immune defense effectors HD-5 and -6: implications for Crohn's disease

(2014) Julia Beisner et al.   AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY

Unusual binding mode of scorpion toxin BmKTX onto potassium channels relies on its distribution of acidic residues

(2014) Zongyun Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endogenous animal toxin-like human β-defensin 2 inhibits own K+ channels through interaction with channel extracellular pore region

(2014) Weishan Yang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Two Conserved Arginine Residues from the SK3 Potassium Channel Outer Vestibule Control Selectivity of Recognition by Scorpion Toxins

(2013) Jing Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Anti-HIV Activity of Human Defensin 5 in Primary CD4+ T Cells under Serum-Deprived Conditions Is a Consequence of Defensin-Mediated Cytotoxicity

(2013) Jian Ding et al.   PLoS One

hERG Potassium Channel Blockage by Scorpion Toxin BmKKx2 Enhances Erythroid Differentiation of Human Leukemia Cells K562

(2013) Jian Ma et al.   PLoS One

Hg1, Novel Peptide Inhibitor Specific for Kv1.3 Channels from First Scorpion Kunitz-type Potassium Channel Toxin Family

(2012) Zong-Yun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Inhibition of CCR7−Effector Memory T Cell Activation by a Novel Peptide Targeting Kv1.3 Channel in a Rat Experimental Autoimmune Encephalomyelitis Model

(2012) Zhi Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural and Functional Diversity of Acidic Scorpion Potassium Channel Toxins

(2012) Zong-Yun Chen et al.   PLoS One

Inhibition of HIV-1 Infection by Human α-Defensin-5, a Natural Antimicrobial Peptide Expressed in the Genital and Intestinal Mucosae

(2012) Lucinda Furci et al.   PLoS One

Human β-defensin-2 enhances IFN-γ and IL-10 production and suppresses IL-17 production in T cells

(2011) Naoko Kanda et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

(2011) Victor Chi et al.   TOXICON

Long‐Term Antibiotic Treatment for Crohn's Disease: Systematic Review and Meta‐Analysis of Placebo‐Controlled Trials

(2010) Martin Feller et al.   CLINICAL INFECTIOUS DISEASES

The functional network of ion channels in T lymphocytes

(2009) Michael D. Cahalan et al.   IMMUNOLOGICAL REVIEWS

Developmental Switch of the Expression of Ion Channels in Human Dendritic Cells

(2009) E. Zsiros et al.   JOURNAL OF IMMUNOLOGY

Animal Toxins Acting on Voltage-Gated Potassium Channels

(2008) Stephanie Mouhat et al.   CURRENT PHARMACEUTICAL DESIGN

Optimization of the Oxidative Folding Reaction and Disulfide Structure Determination of Human α-Defensin 1, 2, 3 and 5

(2008) Shigeru Kubo et al.   International Journal of Peptide Research and Therapeutics

Different Residues in Channel Turret Determining the Selectivity of ADWX-1 Inhibitor Peptide between Kv1.1 and Kv1.3 Channels

(2008) Shi-Jin Yin et al.   JOURNAL OF PROTEOME RESEARCH

Clofazimine Inhibits Human Kv1.3 Potassium Channel by Perturbing Calcium Oscillation in T Lymphocytes

(2008) Yunzhao R. Ren et al.   PLoS One