Plectasin, First Animal Toxin-Like Fungal Defensin Blocking Potassium Channels through Recognizing Channel Pore Region

Sequence diversity and evolution of antimicrobial peptides in invertebrates

(2015) Anchalee Tassanakajon et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Insect antimicrobial peptides and their applications

(2014) Hui-Yu Yi et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Unusual binding mode of scorpion toxin BmKTX onto potassium channels relies on its distribution of acidic residues

(2014) Zongyun Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endogenous animal toxin-like human β-defensin 2 inhibits own K+ channels through interaction with channel extracellular pore region

(2014) Weishan Yang et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Free Energy Simulations of Binding of HsTx1 Toxin to Kv1 Potassium Channels: the Basis of Kv1.3/Kv1.1 Selectivity

(2014) M. Harunur Rashid et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Physiological Role of Kv1.3 Channel in T Lymphocyte Cell Investigated Quantitatively by Kinetic Modeling

(2014) Panpan Hou et al.   PLoS One

Antimicrobial Activity of Defensins and Defensin-Like Peptides with Special Emphasis on those from Fungi and Invertebrate Animals

(2013) Tzi Ng et al.   CURRENT PROTEIN & PEPTIDE SCIENCE

Two Conserved Arginine Residues from the SK3 Potassium Channel Outer Vestibule Control Selectivity of Recognition by Scorpion Toxins

(2013) Jing Feng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structure of a pore-blocking toxin in complex with a eukaryotic voltage-dependent K+ channel

(2013) Anirban Banerjee et al.   eLife

Engineering a Potent and Specific Blocker of Voltage-Gated Potassium Channel Kv1.3, a Target for Autoimmune Diseases

(2012) Rong Chen et al.   BIOCHEMISTRY

Hg1, Novel Peptide Inhibitor Specific for Kv1.3 Channels from First Scorpion Kunitz-type Potassium Channel Toxin Family

(2012) Zong-Yun Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Selective Inhibition of CCR7−Effector Memory T Cell Activation by a Novel Peptide Targeting Kv1.3 Channel in a Rat Experimental Autoimmune Encephalomyelitis Model

(2012) Zhi Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Affinity and Selectivity of ShK Toxin for the Kv1 Potassium Channels from Free Energy Simulations

(2012) M. Harunur Rashid et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Modeling the Binding of Three Toxins to the Voltage-Gated Potassium Channel (Kv1.3)

(2011) Rong Chen et al.   BIOPHYSICAL JOURNAL

Development of a sea anemone toxin as an immunomodulator for therapy of autoimmune diseases

(2011) Victor Chi et al.   TOXICON

Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

(2010) T. Schneider et al.   SCIENCE

Plectasin Shows Intracellular Activity against Staphylococcus aureus in Human THP-1 Monocytes and in a Mouse Peritonitis Model

(2009) K. S. Brinch et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Molecular Information of Charybdotoxin Blockade in the Large Conductance Calcium-activated Potassium Channel

(2009) Su Qiu et al.   Journal of Chemical Information and Modeling

Animal Toxins Acting on Voltage-Gated Potassium Channels

(2008) Stephanie Mouhat et al.   CURRENT PHARMACEUTICAL DESIGN

Structural Basis for Toxin Resistance of β4-Associated Calcium-activated Potassium (BK) Channels

(2008) Geliang Gan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis of a Potent Peptide Inhibitor Designed for Kv1.3 Channel, a Therapeutic Target of Autoimmune Disease

(2008) Song Han et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Different Residues in Channel Turret Determining the Selectivity of ADWX-1 Inhibitor Peptide between Kv1.1 and Kv1.3 Channels

(2008) Shi-Jin Yin et al.   JOURNAL OF PROTEOME RESEARCH