Aquaporin-1 retards renal cyst development in polycystic kidney disease by inhibition of Wnt signaling

The Aquaporin 1 C-Terminal Tail Is Required for Migration and Growth of Pulmonary Arterial Myocytes

(2014) Ning Lai et al.   AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY

Impaired glomerulogenesis and endothelial cell migration in Pkd1-deficient renal organ cultures

(2014) Isaline Rowe et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Polycystin-1 regulates actin cytoskeleton organization and directional cell migration through a novel PC1-Pacsin 2-N-Wasp complex

(2014) G. Yao et al.   HUMAN MOLECULAR GENETICS

Aquaporins: important but elusive drug targets

(2014) Alan S. Verkman et al.   NATURE REVIEWS DRUG DISCOVERY

Pranlukast inhibits renal epithelial cyst progression via activation of AMP-activated protein kinase

(2013) Nutthapoom Pathomthongtaweechai et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

β-Arrestin Promotes Wnt-induced Low Density Lipoprotein Receptor-related Protein 6 (Lrp6) Phosphorylation via Increased Membrane Recruitment of Amer1 Protein

(2013) Vítězslav Kříž et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Type of PKD1 Mutation Influences Renal Outcome in ADPKD

(2013) E. Cornec-Le Gall et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst–forming epithelial cells

(2013) Bjoern Buchholz et al.   KIDNEY INTERNATIONAL

Aquaporin water channels in the nervous system

(2013) Marios C. Papadopoulos et al.   NATURE REVIEWS NEUROSCIENCE

Ex Vivo Modeling of Chemical Synergy in Prenatal Kidney Cystogenesis

(2013) Corina Anders et al.   PLoS One

Wnt Stabilization of  -Catenin Reveals Principles for Morphogen Receptor-Scaffold Assemblies

(2013) S.-E. Kim et al.   SCIENCE

Aqp1 Enhances Migration of Bone Marrow Mesenchymal Stem Cells Through Regulation of FAK and β-Catenin

(2013) Fanbiao Meng et al.   STEM CELLS AND DEVELOPMENT

Wnt Signaling through Inhibition of β-Catenin Degradation in an Intact Axin1 Complex

(2012) Vivian S.W. Li et al.   CELL

GSK3b-inhibitor lithium chloride enhances activation of Wnt canonical signaling and osteoblast differentiation on hydrophilic titanium surfaces

(2012) C. Galli et al.   CLINICAL ORAL IMPLANTS RESEARCH

Wnt signalling in kidney diseases: dual roles in renal injury and repair

(2012) Takahisa Kawakami et al.   JOURNAL OF PATHOLOGY

Aquaporin-1 Translocation and Degradation Mediates the Water Transportation Mechanism of Acetazolamide

(2012) Jianzhao Zhang et al.   PLoS One

Aquaporins at a glance

(2011) A. S. Verkman   JOURNAL OF CELL SCIENCE

WNT/β-catenin signaling in polycystic kidney disease

(2011) Anne Wuebken et al.   KIDNEY INTERNATIONAL

Distinct roles of cadherin-6 and E-cadherin in tubulogenesis and lumen formation

(2011) Liwei Jia et al.   MOLECULAR BIOLOGY OF THE CELL

Deconstructing the ßcatenin destruction complex: mechanistic roles for the tumor suppressor APC in regulating Wnt signaling

(2011) David M. Roberts et al.   MOLECULAR BIOLOGY OF THE CELL

Wnt Signaling Requires Sequestration of Glycogen Synthase Kinase 3 inside Multivesicular Endosomes

(2010) Vincent F. Taelman et al.   CELL

Loss of Bicc1 impairs tubulomorphogenesis of cultured IMCD cells by disrupting E-cadherin-based cell-cell adhesion

(2010) Yulong Fu et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

The expression of E-cadherin-catenin complex in patients with advanced gastric cancer: role in formation of metastasis.

(2010) Jolanta Czyzewska et al.   FOLIA HISTOCHEMICA ET CYTOBIOLOGICA

αE-catenin regulates actin dynamics independently of cadherin-mediated cell–cell adhesion

(2010) Jacqueline M. Benjamin et al.   JOURNAL OF CELL BIOLOGY

Cyclic AMP Suppresses Matrix Metalloproteinase-1 Expression through Inhibition of MAPK and GSK-3β

(2010) Chi-Hyun Park et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Genetic Variation of DKK3 May Modify Renal Disease Severity in ADPKD

(2010) M. Liu et al.   JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY

Aquaporins in kidney pathophysiology

(2010) Yumi Noda et al.   Nature Reviews Nephrology

Cystic kidney disease: the role of Wnt signaling

(2010) Madeline A. Lancaster et al.   TRENDS IN MOLECULAR MEDICINE

AQP1 is not only a water channel

(2010) Caterina La Porta   Cell Adhesion & Migration

Autosomal dominant polycystic kidney disease: the last 3 years

(2009) Vicente E. Torres et al.   KIDNEY INTERNATIONAL

Tankyrase inhibition stabilizes axin and antagonizes Wnt signalling

(2009) Shih-Min A. Huang et al.   NATURE

Inhibition of GSK3 Phosphorylation of β-Catenin via Phosphorylated PPPSPXS Motifs of Wnt Coreceptor LRP6

(2009) Geng Wu et al.   PLoS One

AQP1 Is Not Only a Water Channel: It Contributes to Cell Migration through Lin7/Beta-Catenin

(2009) Elena Monzani et al.   PLoS One

Polycystic Kidney Disease

(2008) Peter C. Harris et al.   Annual Review of Medicine

Acute kidney injury and aberrant planar cell polarity induce cyst formation in mice lacking renal cilia

(2008) Vishal Patel et al.   HUMAN MOLECULAR GENETICS

Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1

(2008) Sekiya Shibazaki et al.   HUMAN MOLECULAR GENETICS

Polycystin-1 C-terminal tail associates with β-catenin and inhibits canonical Wnt signaling

(2008) Mark Lal et al.   HUMAN MOLECULAR GENETICS

Dissecting the Roles of Aquaporins in Renal Pathophysiology Using Transgenic Mice

(2008) A.S. Verkman   SEMINARS IN NEPHROLOGY