New mechanistic insights on the metabolic-disruptor role of chlorpyrifos in apoE mice: a focus on insulin- and leptin-signalling pathways

Exposure to DDT and diabetic nephropathy among Mexican Americans in the 1999–2004 National Health and Nutrition Examination Survey

(2017) Charles J. Everett et al.   ENVIRONMENTAL POLLUTION

Associations between persistent organic pollutants, type 2 diabetes, diabetic nephropathy and mortality

(2017) Brian A Grice et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Retinoic acid exacerbates chlorpyrifos action in ensuing adipogenic differentiation of C3H10T½ cells in a GSK3β dependent pathway

(2017) Harkirat Singh Sandhu et al.   PLoS One

Polyvinyl pyrrolidone-coated silver nanoparticles in a human lung cancer cells: time- and dose-dependent influence over p53 and caspase-3 protein expression and epigenetic effects

(2016) Jordi Blanco et al.   ARCHIVES OF TOXICOLOGY

Naturally Occurring Genetic Variants of Human Acetylcholinesterase and Butyrylcholinesterase and Their Potential Impact on the Risk of Toxicity from Cholinesterase Inhibitors

(2016) Oksana Lockridge et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Paraoxonases-1, -2 and -3: What are their functions?

(2016) Clement E. Furlong et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The occurrence of pesticides and persistent organic pollutants in Italian organic honeys from different productive areas in relation to potential environmental pollution

(2016) L.M. Chiesa et al.   CHEMOSPHERE

Diabetes Prevalence in Relation to Serum Concentrations of Polychlorinated Biphenyl (PCB) Congener Groups and Three Chlorinated Pesticides in a Native American Population

(2016) Zafar Aminov et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Downregulation of human paraoxonase 1 (PON1) by organophosphate pesticides in HepG2 cells

(2016) Irma Martha Medina-Díaz et al.   ENVIRONMENTAL TOXICOLOGY

Apolipoprotein E (APOE) genotype and the pesticide chlorpyrifos modulate attention, motivation and impulsivity in female mice in the 5-choice serial reaction time task

(2016) Fiona Peris-Sampedro et al.   FOOD AND CHEMICAL TOXICOLOGY

Carnosic Acid Affords Mitochondrial Protection in Chlorpyrifos-Treated Sh-Sy5y Cells

(2016) Marcos Roberto de Oliveira et al.   NEUROTOXICITY RESEARCH

Spatio-temporal patterns of pesticide residues in the Turia and Júcar Rivers (Spain)

(2016) Alexander Ccanccapa et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Exposure to chlorpyrifos increases neutral lipid accumulation with accompanying increased de novo lipogenesis and decreased triglyceride secretion in McArdle-RH7777 hepatoma cells

(2016) George Eli Howell III et al.   TOXICOLOGY IN VITRO

Inulin Supplementation Lowered the Metabolic Defects of Prolonged Exposure to Chlorpyrifos from Gestation to Young Adult Stage in Offspring Rats

(2016) Julie Reygner et al.   PLoS One

Azinphos-methyl and chlorpyrifos, alone or in a binary mixture, produce oxidative stress and lipid peroxidation in the freshwater gastropod Planorbarius corneus

(2015) Luis C. Cacciatore et al.   AQUATIC TOXICOLOGY

The role of vitamin C as antioxidant in protection of biochemical and haematological stress induced by chlorpyrifos in freshwater fish Clarias batrachus

(2015) Madhusudan Reddy Narra et al.   CHEMOSPHERE

Endocrine disruptors: New players in the pathophysiology of type 2 diabetes?

(2015) N. Chevalier et al.   DIABETES & METABOLISM

Persistent organic pollutants in young adults and changes in glucose related metabolism over a 23-year follow-up

(2015) Jose R. Suarez-Lopez et al.   ENVIRONMENTAL RESEARCH

Adulthood dietary exposure to a common pesticide leads to an obese-like phenotype and a diabetic profile in apoE3 mice

(2015) Fiona Peris-Sampedro et al.   ENVIRONMENTAL RESEARCH

PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis

(2015) Diana M. Shih et al.   FASEB JOURNAL

Chronic exposure to chlorpyrifos triggered body weight increase and memory impairment depending on human apoE polymorphisms in a targeted replacement mouse model

(2015) Fiona Peris-Sampedro et al.   PHYSIOLOGY & BEHAVIOR

Attentional performance, impulsivity, and related neurotransmitter systems in apoE2, apoE3, and apoE4 female transgenic mice

(2015) Ingrid Reverte et al.   PSYCHOPHARMACOLOGY

Modifying Effects of Vitamin E on Chlorpyrifos Toxicity in Atlantic Salmon

(2015) Pål A. Olsvik et al.   PLoS One

Exposure to Persistent Organic Pollutants: Relationship With Abnormal Glucose Metabolism and Visceral Adiposity

(2014) Eveline L. Dirinck et al.   DIABETES CARE

Biomonitoring exposure assessment to contemporary pesticides in a school children population of Spain

(2014) Marta Roca et al.   ENVIRONMENTAL RESEARCH

Apolipoprotein E (APOE) genotype regulates body weight and fatty acid utilization-Studies in gene-targeted replacement mice

(2014) Patricia Huebbe et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Nuclear NF-κB contributes to chlorpyrifos-induced apoptosis through p53 signaling in human neural precursor cells

(2014) Jeong Eun Lee et al.   NEUROTOXICOLOGY

Neurodevelopmental effects of decabromodiphenyl ether (BDE-209) in APOE transgenic mice

(2014) Ingrid Reverte et al.   NEUROTOXICOLOGY AND TERATOLOGY

Pesticide use and incident diabetes among wives of farmers in the Agricultural Health Study

(2014) Anne P Starling et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Thyroid hormones and fear learning but not anxiety are affected in adult apoE transgenic mice exposed postnatally to decabromodiphenyl ether (BDE-209)

(2014) Ingrid Reverte et al.   PHYSIOLOGY & BEHAVIOR

Repeated Gestational Exposure of Mice to Chlorpyrifos Oxon Is Associated with Paraoxonase 1 (PON1) Modulated Effects in Maternal and Fetal Tissues

(2014) Toby B. Cole et al.   TOXICOLOGICAL SCIENCES

A review on the molecular mechanisms involved in insulin resistance induced by organophosphorus pesticides

(2014) Mohamed Montassar Lasram et al.   TOXICOLOGY

Protective role of Nigella sativa oil against reproductive toxicity, hormonal alterations, and oxidative damage induced by chlorpyrifos in male rats

(2014) Rachid Mosbah et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Inactivation of SOCS3 in leptin receptor-expressing cells protects mice from diet-induced insulin resistance but does not prevent obesity

(2014) João A.B. Pedroso et al.   Molecular Metabolism

Influence of organophosphate poisoning on human dendritic cells

(2013) Marina Schäfer et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Low level chlorpyrifos exposure increases anandamide accumulation in juvenile rat brain in the absence of brain cholinesterase inhibition

(2013) Russell L. Carr et al.   NEUROTOXICOLOGY

Long term effects of murine postnatal exposure to decabromodiphenyl ether (BDE-209) on learning and memory are dependent upon APOE polymorphism and age

(2013) Ingrid Reverte et al.   NEUROTOXICOLOGY AND TERATOLOGY

Perinatal exposure to BDE-99 causes learning disorders and decreases serum thyroid hormone levels and BDNF gene expression in hippocampus in rat offspring

(2013) Jordi Blanco et al.   TOXICOLOGY

Interactions of neuropathy inducers and potentiators/promoters with soluble esterases

(2012) Jorge Estévez et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Chlorpyrifos acute exposure induces hyperglycemia and hyperlipidemia in rats

(2012) Carmine Inês Acker et al.   CHEMOSPHERE

Total diet study on pesticide residues in France: Levels in food as consumed and chronic dietary risk to consumers

(2012) Alexandre Nougadère et al.   ENVIRONMENT INTERNATIONAL

Chlorpyrifos and neurodevelopmental effects: a literature review and expert elicitation on research and policy

(2012) Margaret Saunders et al.   Environmental Health

Role of Environmental Chemicals in Diabetes and Obesity: A National Toxicology Program Workshop Review

(2012) Kristina A. Thayer et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Sub-chronic exposure to chlorpyrifos induces hematological, metabolic disorders and oxidative stress in rat: Attenuation by glutathione

(2012) Eman E. Elsharkawy et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Behavioral phenotype and BDNF differences related to apoE isoforms and sex in young transgenic mice

(2012) Ingrid Reverte et al.   EXPERIMENTAL NEUROLOGY

Gestational Exposure to BDE-99 Produces Toxicity Through Upregulation of CYP Isoforms and ROS Production in the Fetal Rat Liver

(2012) Jordi Blanco et al.   TOXICOLOGICAL SCIENCES

Effect of CYP2B6*6 and CYP2C19*2 genotype on chlorpyrifos metabolism

(2012) Alice L. Crane et al.   TOXICOLOGY

Chlorpyrifos and its metabolites alter gene expression at non-cytotoxic concentrations in D3 mouse embryonic stem cells under in vitro differentiation: Considerations for embryotoxic risk assessment

(2012) Carmen Estevan et al.   TOXICOLOGY LETTERS

Amyloid β Peptide Levels Increase in Brain of AβPP Swedish Mice after Exposure to Chlorpyrifos

(2011) Jose G. Salazar et al.   Current Alzheimer Research

Effects of sub-lethal neurite outgrowth inhibitory concentrations of chlorpyrifos oxon on cytoskeletal proteins and acetylcholinesterase in differentiating N2a cells

(2011) J. Flaskos et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxon

(2011) J. Allen Crow et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Serum albumins and detoxication of anti-cholinesterase agents

(2010) Miguel A. Sogorb et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Correlating neurobehavioral performance with biomarkers of organophosphorous pesticide exposure

(2010) Diane S. Rohlman et al.   NEUROTOXICOLOGY

Does early-life exposure to organophosphate insecticides lead to prediabetes and obesity?

(2010) Theodore A. Slotkin   REPRODUCTIVE TOXICOLOGY

Incident Diabetes and Pesticide Exposure among Licensed Pesticide Applicators: Agricultural Health Study, 1993-2003

(2008) M. P. Montgomery et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Subtoxic chlorpyrifos treatment resulted in differential expression of genes implicated in neurological functions and development

(2008) Andrea R. Stapleton et al.   ARCHIVES OF TOXICOLOGY

Review of the Toxicology of Chlorpyrifos With an Emphasis on Human Exposure and Neurodevelopment

(2008) David L. Eaton et al.   CRITICAL REVIEWS IN TOXICOLOGY

Apolipoprotein E predisposes to obesity and related metabolic dysfunctions in mice

(2008) Iordanes Karagiannides et al.   FEBS Journal

Differential modulation of diet-induced obesity and adipocyte functionality by human apolipoprotein E3 and E4 in mice

(2008) J M Arbones-Mainar et al.   INTERNATIONAL JOURNAL OF OBESITY

GSK-3β down-regulates the transcription factor Nrf2 after oxidant damage: relevance to exposure of neuronal cells to oxidative stress

(2008) Ana I. Rojo et al.   JOURNAL OF NEUROCHEMISTRY

Rats gain excess weight after developmental exposure to the organophosphorothionate pesticide, chlorpyrifos

(2007) T. Leon Lassiter et al.   NEUROTOXICOLOGY AND TERATOLOGY