Genetically engineered fusion of MAP-1 and factor H domains 1–5 generates a potent dual upstream inhibitor of both the lectin and alternative complement pathways

Structural Insights into the Initiating Complex of the Lectin Pathway of Complement Activation

(2015) Troels R. Kjaer et al.   STRUCTURE

A novel CRIg-targeted complement inhibitor protects cells from complement damage

(2014) Qian Qiao et al.   FASEB JOURNAL

Essential Role for the Lectin Pathway in Collagen Antibody–Induced Arthritis Revealed through Use of Adenovirus Programming Complement Inhibitor MAp44 Expression

(2014) Nirmal K. Banda et al.   JOURNAL OF IMMUNOLOGY

Complement in paroxysmal nocturnal hemoglobinuria: exploiting our current knowledge to improve the treatment landscape

(2014) Dimitrios C Mastellos et al.   Expert Review of Hematology

Heteromeric Complexes of Native Collectin Kidney 1 and Collectin Liver 1 Are Found in the Circulation with MASPs and Activate the Complement System

(2013) M. L. Henriksen et al.   JOURNAL OF IMMUNOLOGY

Rational Engineering of a Minimized Immune Inhibitor with Unique Triple-Targeting Properties

(2013) C. Q. Schmidt et al.   JOURNAL OF IMMUNOLOGY

An Engineered Construct Combining Complement Regulatory and Surface-Recognition Domains Represents a Minimal-Size Functional Factor H

(2013) M. Hebecker et al.   JOURNAL OF IMMUNOLOGY

Complement in Immune and Inflammatory Disorders: Pathophysiological Mechanisms

(2013) D. Ricklin et al.   JOURNAL OF IMMUNOLOGY

Complement in Immune and Inflammatory Disorders: Therapeutic Interventions

(2013) D. Ricklin et al.   JOURNAL OF IMMUNOLOGY

Fusion protein linkers: Property, design and functionality

(2012) Xiaoying Chen et al.   ADVANCED DRUG DELIVERY REVIEWS

Endogenous and Natural Complement Inhibitor Attenuates Myocardial Injury and Arterial Thrombogenesis

(2012) Vasile I. Pavlov et al.   CIRCULATION

Complement dysregulation and disease: From genes and proteins to diagnostics and drugs

(2012) Santiago Rodriguez de Cordoba et al.   IMMUNOBIOLOGY

Crystal Structure and Functional Characterization of the Complement Regulator Mannose-binding Lectin (MBL)/Ficolin-associated Protein-1 (MAP-1)

(2012) Mikkel-Ole Skjoedt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Collectin-11/MASP Complex Formation Triggers Activation of the Lectin Complement Pathway - The Fifth Lectin Pathway Initiation Complex

(2012) Ying Jie Ma et al.   Journal of Innate Immunity

Revised mechanism of complement lectin-pathway activation revealing the role of serine protease MASP-1 as the exclusive activator of MASP-2

(2012) D. Heja et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and development of TT30, a novel C3d-targeted C3/C5 convertase inhibitor for treatment of human complement alternative pathway-mediated diseases

(2011) M. Fridkis-Hareli et al.   BLOOD

Complement and glomerular disease: new insights

(2011) Matthew Pickering et al.   CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION

Serum concentration and interaction properties of MBL/ficolin associated protein-1

(2010) Mikkel-Ole Skjoedt et al.   IMMUNOBIOLOGY

A Novel Mannose-binding Lectin/Ficolin-associated Protein Is Highly Expressed in Heart and Skeletal Muscle Tissues and Inhibits Complement Activation

(2010) Mikkel-Ole Skjoedt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Complement control protein factor H: The good, the bad, and the inadequate

(2010) Viviana P. Ferreira et al.   MOLECULAR IMMUNOLOGY

Complement: a key system for immune surveillance and homeostasis

(2010) Daniel Ricklin et al.   NATURE IMMUNOLOGY

Functional Analysis of Ficolin-3 Mediated Complement Activation

(2010) Estrid Hein et al.   PLoS One

MBL-associated serine protease-3 circulates in high serum concentrations predominantly in complex with Ficolin-3 and regulates Ficolin-3 mediated complement activation

(2009) Mikkel-Ole Skjoedt et al.   IMMUNOBIOLOGY

MAp44, a Human Protein Associated with Pattern Recognition Molecules of the Complement System and Regulating the Lectin Pathway of Complement Activation

(2009) S. E. Degn et al.   JOURNAL OF IMMUNOLOGY

MBL2, FCN1, FCN2 and FCN3—The genes behind the initiation of the lectin pathway of complement

(2009) Peter Garred et al.   MOLECULAR IMMUNOLOGY

Immunodeficiency Associated withFCN3Mutation and Ficolin-3 Deficiency

(2009) Lea Munthe-Fog et al.   NEW ENGLAND JOURNAL OF MEDICINE

Crystal Structure of the CUB1-EGF-CUB2Domain of Human MASP-1/3 and Identification of Its Interaction Sites with Mannan-binding Lectin and Ficolins

(2008) Florence Teillet et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The alternative complement pathway revisited

(2008) Morten Harboe et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Discrimination between host and pathogens by the complement system

(2008) Michael K. Pangburn et al.   VACCINE

Comparative study of the human ficolins reveals unique features of Ficolin-3 (Hakata antigen)

(2007) Tina Hummelshoj et al.   MOLECULAR IMMUNOLOGY