Synthesis, cytotoxicity and anti-metastatic properties of new pyridyl-thiazole arene ruthenium(II) complexes

Discovery of a series of ruthenium(II) derivatives with α -dicarbonylmonoxime as novel inhibitors of cancer cells invasion and metastasis

(2017) Yihui He et al.   JOURNAL OF ORGANOMETALLIC CHEMISTRY

Microwave-assisted synthesis of polypyridyl ruthenium(ii) complexes as potential tumor-targeting inhibitors against the migration and invasion of Hela cells through G2/M phase arrest

(2017) Jieqiong Cao et al.   RSC Advances

Arene Ruthenium(II) Complexes as Low-Toxicity Inhibitor against the Proliferation, Migration, and Invasion of MDA-MB-231 Cells through Binding and Stabilizing c-myc G-Quadruplex DNA

(2016) Qiong Wu et al.   ORGANOMETALLICS

Cisplatin resistance and opportunities for precision medicine

(2016) Lauren Amable   PHARMACOLOGICAL RESEARCH

Cell cycle arrest is not senescence

(2016) Mikhail V. Blagosklonny   Aging-US

Induction of Cytotoxicity in Pyridine Analogues of the Anti-metastatic Ru(III) Complex NAMI-A by Ferrocene Functionalization

(2015) Changhua Mu et al.   INORGANIC CHEMISTRY

Synthesis, Anticancer Activity, and Genome Profiling of Thiazolo Arene Ruthenium Complexes

(2015) Adriana Grozav et al.   JOURNAL OF MEDICINAL CHEMISTRY

Water-Soluble Ruthenium(II) Complexes with Chiral 4-(2,3-Dihydroxypropyl)-formamide Oxoaporphine (FOA): In Vitro and in Vivo Anticancer Activity by Stabilization of G-Quadruplex DNA, Inhibition of Telomerase Activity, and Induction of Tumor Cell Apoptosis

(2015) Zhen-Feng Chen et al.   JOURNAL OF MEDICINAL CHEMISTRY

Cisplatin in cancer therapy: Molecular mechanisms of action

(2014) Shaloam Dasari et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The Synthesis and Antiproliferative Activities of New Arylidene-Hydrazinyl-Thiazole Derivatives

(2014) Adriana Grozav et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Modification and Biological Evaluation of Thiazole Derivatives as Novel Inhibitors of Metastatic Cancer Cell Migration and Invasion

(2014) Shilong Zheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

Discovery and Investigation of Anticancer Ruthenium–Arene Schiff-Base Complexes via Water-Promoted Combinatorial Three-Component Assembly

(2014) Mun Juinn Chow et al.   JOURNAL OF MEDICINAL CHEMISTRY

In Vitro and in Vivo Evaluation of Water-Soluble Iminophosphorane Ruthenium(II) Compounds. A Potential Chemotherapeutic Agent for Triple Negative Breast Cancer

(2014) Malgorzata Frik et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthesis and biological evaluation of 2-aminothiazole derivatives as antimycobacterial and antiplasmodial agents

(2013) Faith Mjambili et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Discovery of Potent and Selective Benzothiazole Hydrazone Inhibitors of Bcl-XL

(2013) Brad E. Sleebs et al.   JOURNAL OF MEDICINAL CHEMISTRY

The Contrasting Activity of Iodido versus Chlorido Ruthenium and Osmium Arene Azo- and Imino-pyridine Anticancer Complexes: Control of Cell Selectivity, Cross-Resistance, p53 Dependence, and Apoptosis Pathway

(2013) Isolda Romero-Canelón et al.   JOURNAL OF MEDICINAL CHEMISTRY

Heterocycles 27. Microwave Assisted Synthesis and Antitumour Activity of Novel Phenothiazinyl-Thiazolyl-Hydrazine Derivatives

(2012) Adriana Ignat et al.   ARCHIV DER PHARMAZIE

Virtual Screening and Optimization Yield Low-Nanomolar Inhibitors of the Tautomerase Activity of Plasmodium falciparum Macrophage Migration Inhibitory Factor

(2012) Markus K. Dahlgren et al.   JOURNAL OF MEDICINAL CHEMISTRY

Metal-based antitumour drugs in the post-genomic era: what comes next?

(2011) Gianni Sava et al.   DALTON TRANSACTIONS

Ruthenium-based chemotherapeutics: are they ready for prime time?

(2010) Emmanuel S. Antonarakis et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

The anti-cancer properties of gold(III) compounds with dianionic porphyrin and tetradentate ligands

(2009) Raymond Wai-Yin Sun et al.   COORDINATION CHEMISTRY REVIEWS

Metal Complexes, their Cellular Targets and Potential for Cancer Therapy

(2009) Di Chen et al.   CURRENT PHARMACEUTICAL DESIGN

KP1019, A New Redox-Active Anticancer Agent - Preclinical Development and Results of a Clinical Phase I Study in Tumor Patients

(2008) Christian G. Hartinger et al.   CHEMISTRY & BIODIVERSITY

p53: A Guide to Apoptosis

(2008) Erik Meulmeester et al.   CURRENT CANCER DRUG TARGETS

New trends for metal complexes with anticancer activity

(2008) Pieter CA Bruijnincx et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

The ruthenium(II)–arene compound RAPTA-C induces apoptosis in EAC cells through mitochondrial and p53–JNK pathways

(2008) Soumya Chatterjee et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

New Antitumor Imidazo[2,1-b]thiazole Guanylhydrazones and Analogues1

(2008) Aldo Andreani et al.   JOURNAL OF MEDICINAL CHEMISTRY