In Vitro and In Vivo Activities of DS86760016, a Novel Leucyl-tRNA Synthetase Inhibitor for Gram-Negative Pathogens

Discovery of Novel Oral Protein Synthesis Inhibitors of Mycobacterium tuberculosis That Target Leucyl-tRNA Synthetase

(2016) Andrés Palencia et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Benzoxaborole Antimalarial Agents. Part 4. Discovery of Potent 6-(2-(Alkoxycarbonyl)pyrazinyl-5-oxy)-1,3-dihydro-1-hydroxy-2,1-benzoxaboroles

(2015) Yong-Kang Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Mechanisms of antimicrobial resistance in Gram-negative bacilli

(2015) Étienne Ruppé et al.   Annals of Intensive Care

Bacterial Resistance to Leucyl-tRNA Synthetase Inhibitor GSK2251052 Develops during Treatment of Complicated Urinary Tract Infections

(2014) Karen O'Dwyer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discovery of a Novel Class of Boron-Based Antibacterials with Activity against Gram-Negative Bacteria

(2013) Vincent Hernandez et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Discovery of a potent benzoxaborole-based anti-pneumococcal agent targeting leucyl-tRNA synthetase

(2013) Qing-Hua Hu et al.   Scientific Reports

Aminoacyl-tRNA synthetase inhibitors as potential antibiotics

(2011) Gaston H.M. Vondenhoff et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

SCYX-7158, an Orally-Active Benzoxaborole for the Treatment of Stage 2 Human African Trypanosomiasis

(2011) Robert T. Jacobs et al.   PLoS Neglected Tropical Diseases

Hospital-Acquired Infections Due to Gram-Negative Bacteria

(2010) Anton Y. Peleg et al.   NEW ENGLAND JOURNAL OF MEDICINE

Discovery of Novel Benzoxaborole-Based Potent Antitrypanosomal Agents

(2010) Dazhong Ding et al.   ACS Medicinal Chemistry Letters

Economic burden of healthcare-associated infections: an American perspective

(2009) Patricia W Stone   Expert Review of Pharmacoeconomics & Outcomes Research