Distinct patterns of gene expression in human cardiac fibroblasts exposed to rapamycin treatment or methionine restriction

Rapamycin transiently induces mitochondrial remodeling to reprogram energy metabolism in old hearts

(2016) Ying Ann Chiao et al.   Aging-US

CXCR4 signaling in health and disease

(2016) Tommaso Pozzobon et al.   IMMUNOLOGY LETTERS

The Living Scar – Cardiac Fibroblasts and the Injured Heart

(2016) Eva A. Rog-Zielinska et al.   TRENDS IN MOLECULAR MEDICINE

Emerging Strategies to Enhance Homing and Engraftment of Hematopoietic Stem Cells

(2015) Mariusz Z. Ratajczak et al.   Stem Cell Reviews and Reports

Similarities in Gene Expression Profiles duringIn VitroAging of Primary Human Embryonic Lung and Foreskin Fibroblasts

(2015) Shiva Marthandan et al.   Biomed Research International

Emerging Strategies to Enhance Homing and Engraftment of Hematopoietic Stem Cells

(2015) Mariusz Z. Ratajczak et al.   Stem Cell Reviews and Reports

A comparison of oncogene-induced senescence and replicative senescence: implications for tumor suppression and aging

(2014) David M. Nelson et al.   AGE

Growth hormone signaling is necessary for lifespan extension by dietary methionine

(2014) Holly M. Brown-Borg et al.   AGING CELL

Methionine restriction slows down senescence in human diploid fibroblasts

(2014) Rafał Kozieł et al.   AGING CELL

Autophagy is required for extension of yeast chronological life span by rapamycin

(2014) Ashley L. Alvers et al.   Autophagy

Methionine Restriction Activates the Retrograde Response and Confers Both Stress Tolerance and Lifespan Extension to Yeast, Mouse and Human Cells

(2014) Jay E. Johnson et al.   PLoS One

Lifespan Extension by Methionine Restriction Requires Autophagy-Dependent Vacuolar Acidification

(2014) Christoph Ruckenstuhl et al.   PLoS Genetics

Reduced mammalian target of rapamycin activity facilitates mitochondrial retrograde signaling and increases life span in normal human fibroblasts

(2013) Chad Lerner et al.   AGING CELL

Regulation of longevity and oxidative stress by nutritional interventions: Role of methionine restriction

(2013) Ines Sanchez-Roman et al.   EXPERIMENTAL GERONTOLOGY

Senescent Cardiac Fibroblast Is Critical for Cardiac Fibrosis after Myocardial Infarction

(2013) Fuli Zhu et al.   PLoS One

Aging, Cellular Senescence, and Cancer

(2012) Judith Campisi   Annual Review of Physiology

Rapamycin Reverses Elevated mTORC1 Signaling in Lamin A/C-Deficient Mice, Rescues Cardiac and Skeletal Muscle Function, and Extends Survival

(2012) F. J. Ramos et al.   Science Translational Medicine

The practical effect of batch on genomic prediction

(2012) Hilary S. Parker et al.   Statistical Applications in Genetics and Molecular Biology

VennDiagram: a package for the generation of highly-customizable Venn and Euler diagrams in R

(2011) Hanbo Chen et al.   BMC BIOINFORMATICS

Forty percent methionine restriction lowers DNA methylation, complex I ROS generation, and oxidative damage to mtDNA and mitochondrial proteins in rat heart

(2011) Ines Sanchez-Roman et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Four faces of cellular senescence

(2011) Francis Rodier et al.   JOURNAL OF CELL BIOLOGY

The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression

(2010) Jean-Philippe Coppé et al.   Annual Review of Pathology-Mechanisms of Disease

Mechanisms of Life Span Extension by Rapamycin in the Fruit Fly Drosophila melanogaster

(2010) Ivana Bjedov et al.   Cell Metabolism

Rapamycin, But Not Resveratrol or Simvastatin, Extends Life Span of Genetically Heterogeneous Mice

(2010) Richard A. Miller et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Myocardial Fibrosis as an Early Manifestation of Hypertrophic Cardiomyopathy

(2010) Carolyn Y. Ho et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Human-Like Senescence-Associated Secretory Phenotype Is Conserved in Mouse Cells Dependent on Physiological Oxygen

(2010) Jean-Philippe Coppé et al.   PLoS One

Long-Term IGF-I Exposure Decreases Autophagy and Cell Viability

(2010) Alessandro Bitto et al.   PLoS One

Cardiac Fibroblast

(2009) Colby A. Souders et al.   CIRCULATION RESEARCH

Rapamycin fed late in life extends lifespan in genetically heterogeneous mice

(2009) David E. Harrison et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor

(2008) Jean-Philippe Coppé et al.   PLOS BIOLOGY