Challenging the current model of early-onset myasthenia gravis pathogenesis in the light of the MGTX trial and histological heterogeneity of thymectomy specimens

From IPEX syndrome to FOXP3 mutation: a lesson on immune dysregulation

(2016) Rosa Bacchetta et al.   Annals of the New York Academy of Sciences

Review on Toll-Like Receptor Activation in Myasthenia Gravis: Application to the Development of New Experimental Models

(2016) Marieke Robinet et al.   CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY

Myasthenia gravis: subgroup classifications – Authors' reply

(2016) Nils Erik Gilhus et al.   LANCET NEUROLOGY

Myasthenia gravis — autoantibody characteristics and their implications for therapy

(2016) Nils Erik Gilhus et al.   Nature Reviews Neurology

Randomized Trial of Thymectomy in Myasthenia Gravis

(2016) Gil I. Wolfe et al.   NEW ENGLAND JOURNAL OF MEDICINE

Self-Antigen-Driven Thymic B Cell Class Switching Promotes T Cell Central Tolerance

(2016) Jason Perera et al.   Cell Reports

Complicating autoimmune diseases in myasthenia gravis: a review

(2015) Aliona Nacu et al.   AUTOIMMUNITY

Thymoma related myasthenia gravis in humans and potential animal models

(2015) Alexander Marx et al.   EXPERIMENTAL NEUROLOGY

Thymic B Cells Are Licensed to Present Self Antigens for Central T Cell Tolerance Induction

(2015) Tomoyoshi Yamano et al.   IMMUNITY

Foxn1 Protein Expression in the Developing, Aging, and Regenerating Thymus

(2015) Immanuel Rode et al.   JOURNAL OF IMMUNOLOGY

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(2015) Michael Seldin et al.   MOLECULAR MEDICINE

A Genome-Wide Association Study of Myasthenia Gravis

(2015) Alan E. Renton et al.   JAMA Neurology

Distinct Contributions of Aire and Antigen-Presenting-Cell Subsets to the Generation of Self-Tolerance in the Thymus

(2014) Justin S.A. Perry et al.   IMMUNITY

Late-onset myasthenia gravis – CTLA4low genotype association and low-for-age thymic output of naïve T cells

(2014) Wen-Yu Chuang et al.   JOURNAL OF AUTOIMMUNITY

Central role of interferon-beta in thymic events leading to myasthenia gravis

(2014) Perrine Cufi et al.   JOURNAL OF AUTOIMMUNITY

Myasthenia gravis: A comprehensive review of immune dysregulation and etiological mechanisms

(2014) Sonia Berrih-Aknin et al.   JOURNAL OF AUTOIMMUNITY

Meis1 Is Required for the Maintenance of Postnatal Thymic Epithelial Cells

(2014) Takehiro Hirayama et al.   PLoS One

The different roles of the thymus in the pathogenesis of the various myasthenia gravis subtypes

(2013) Alexander Marx et al.   AUTOIMMUNITY REVIEWS

Ectopic germinal centers, BAFF and anti-B-cell therapy in myasthenia gravis

(2013) Sonia Berrih-Aknin et al.   AUTOIMMUNITY REVIEWS

S1P lyase in thymic perivascular spaces promotes egress of mature thymocytes via up-regulation of S1P receptor 1

(2013) Yasuhiro Maeda et al.   INTERNATIONAL IMMUNOLOGY

Inactivation of the RB family prevents thymus involution and promotes thymic function by direct control of Foxn1 expression

(2013) Phillip M. Garfin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Autoreactive thymic B cells are efficient antigen-presenting cells of cognate self-antigens for T cell negative selection

(2013) J. Perera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Impact of Aging on Regulatory T-Cells

(2013) Johannes Fessler et al.   Frontiers in Immunology

Risk for myasthenia gravis maps to a151Pro→Ala change in TNIP1 and to human leukocyte antigen-B*08

(2012) Peter K. Gregersen et al.   ANNALS OF NEUROLOGY

Thymus pathology observed in the MGTX trial

(2012) Alexander Marx et al.   Annals of the New York Academy of Sciences

SDF-1/CXCL12 recruits B cells and antigen-presenting cells to the thymus of autoimmune myasthenia gravis patients

(2012) Julia Miriam Weiss et al.   IMMUNOBIOLOGY

Anti-MuSK- and anti-AChR-positive myasthenia gravis induced by d-penicillamine

(2012) Konstantinos Poulas et al.   JOURNAL OF NEUROIMMUNOLOGY

Late Onset Myasthenia Gravis Is Associated with HLA DRB1*15:01 in the Norwegian Population

(2012) Angelina H. Maniaol et al.   PLoS One

Epstein-barr virus in myasthenia gravis thymus: A matter of debate

(2011) Barbara Serafini et al.   ANNALS OF NEUROLOGY

Overexpression of Foxn1 attenuates age-associated thymic involution and prevents the expansion of peripheral CD4 memory T cells

(2011) E. C. Zook et al.   BLOOD

Proteasome Inhibition with Bortezomib Depletes Plasma Cells and Autoantibodies in Experimental Autoimmune Myasthenia Gravis

(2011) A. M. Gomez et al.   JOURNAL OF IMMUNOLOGY

Thymoma and paraneoplastic myasthenia gravis

(2010) A. Marx et al.   AUTOIMMUNITY

Aire, Master of Many Trades

(2010) Bruno Kyewski et al.   CELL

Thymic Stromal Lymphopoietin-Activated Plasmacytoid Dendritic Cells Induce the Generation of FOXP3+ Regulatory T Cells in Human Thymus

(2010) S. Hanabuchi et al.   JOURNAL OF IMMUNOLOGY

Lymphotoxin Signals from Positively Selected Thymocytes Regulate the Terminal Differentiation of Medullary Thymic Epithelial Cells

(2010) A. J. White et al.   JOURNAL OF IMMUNOLOGY

CCL21 overexpressed on lymphatic vessels drives thymic hyperplasia in myasthenia

(2009) Sonia Berrih-Aknin et al.   ANNALS OF NEUROLOGY

Autoimmunizing Mechanisms in Thymoma and Thymus

(2008) Nick Willcox et al.   Annals of the New York Academy of Sciences

Common Cellular and Diverse Genetic Basis of Thymoma-associated Myasthenia Gravis

(2008) Philipp Ströbel et al.   Annals of the New York Academy of Sciences

Foxn1 is required to maintain the postnatal thymic microenvironment in a dosage-sensitive manner

(2008) L. Chen et al.   BLOOD

Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance

(2008) Masashi Yano et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The ageing and myasthenic thymus: A morphometric study validating a standard procedure in the histological workup of thymic specimens

(2008) Philipp Ströbel et al.   JOURNAL OF NEUROIMMUNOLOGY