Cytoreductive conditioning for severe combined immunodeficiency – help or hindrance?

In utero depletion of fetal hematopoietic stem cells improves engraftment after neonatal transplantation in mice

(2014) S. C. Derderian et al.   BLOOD

Newborn Screening for Severe Combined Immunodeficiency in 11 Screening Programs in the United States

(2014) Antonia Kwan et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Comparison of outcomes of hematopoietic stem cell transplantation without chemotherapy conditioning by using matched sibling and unrelated donors for treatment of severe combined immunodeficiency

(2014) Christopher C. Dvorak et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Host natural killer immunity is a key indicator of permissiveness for donor cell engraftment in patients with severe combined immunodeficiency

(2014) Amel Hassan et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Transplantation Outcomes for Severe Combined Immunodeficiency, 2000–2009

(2014) Sung-Yun Pai et al.   NEW ENGLAND JOURNAL OF MEDICINE

A trial of alemtuzumab adjunctive therapy in allogeneic hematopoietic cell transplantation with minimal conditioning for severe combined immunodeficiency

(2014) Christopher C. Dvorak et al.   PEDIATRIC TRANSPLANTATION

SCID patients with ARTEMIS vs RAG deficiencies following HCT: increased risk of late toxicity in ARTEMIS-deficient SCID

(2013) C. Schuetz et al.   BLOOD

B-cell reconstitution for SCID: Should a conditioning regimen be used in SCID treatment?

(2013) Elie Haddad et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

Reduced-intensity conditioning and HLA-matched haemopoietic stem-cell transplantation in patients with chronic granulomatous disease: a prospective multicentre study

(2013) Tayfun Güngör et al.   LANCET

Outcome of hematopoietic stem cell transplantation for adenosine deaminase-deficient severe combined immunodeficiency

(2012) A. Hassan et al.   BLOOD

Treosulfan-based conditioning regimens for hematopoietic stem cell transplantation in children with primary immunodeficiency: United Kingdom experience

(2011) M. A. Slatter et al.   BLOOD

IL-21 is the primary common   chain-binding cytokine required for human B-cell differentiation in vivo

(2011) M. Recher et al.   BLOOD

Neonatal diagnosis of severe combined immunodeficiency leads to significantly improved survival outcome: the case for newborn screening

(2011) L. Brown et al.   BLOOD

Educational paper

(2011) Mirjam van der Burg et al.   EUROPEAN JOURNAL OF PEDIATRICS

Long-term Clinical Outcome of Patients with Severe Combined Immunodeficiency Who Received Related Donor Bone Marrow Transplants without Pretransplant Chemotherapy or Post-transplant GVHD Prophylaxis

(2009) Mary Dell Railey et al.   JOURNAL OF PEDIATRICS

Haemopoietic stem-cell transplantation with antibody-based minimal-intensity conditioning: a phase 1/2 study

(2009) Karin C Straathof et al.   LANCET