Stem cell therapies for systemic lupus erythematosus: current progress and established evidence

Optimizing outcome in SLE: treating-to-target and definition of treatment goals

(2014) Andrea Doria et al.   AUTOIMMUNITY REVIEWS

Allogeneic mesenchymal stem cell transplantation for lupus nephritis patients refractory to conventional therapy

(2014) Fei Gu et al.   CLINICAL RHEUMATOLOGY

Systemic lupus erythematosus

(2014) Larissa Lisnevskaia et al.   LANCET

High level of reactive oxygen species impaired mesenchymal stem cell migration via overpolymerization of F-actin cytoskeleton in systemic lupus erythematosus

(2014) D. Shi et al.   PATHOLOGIE BIOLOGIE

Hydroxychloroquine: A multifaceted treatment in lupus

(2014) Nathalie Costedoat-Chalumeau et al.   PRESSE MEDICALE

Umbilical cord mesenchymal stem cell transplantation in active and refractory systemic lupus erythematosus: a multicenter clinical study

(2014) Dandan Wang et al.   ARTHRITIS RESEARCH & THERAPY

A CD8 T Cell/Indoleamine 2,3-Dioxygenase Axis Is Required for Mesenchymal Stem Cell Suppression of Human Systemic Lupus Erythematosus

(2014) Dandan Wang et al.   Arthritis & Rheumatology

Restored Immunosuppressive Effect of Mesenchymal Stem Cells on B Cells After Olfactory 1/Early B Cell Factor-Associated Zinc-Finger Protein Down-Regulation in Patients With Systemic Lupus Erythematosus

(2014) Xuebing Feng et al.   Arthritis & Rheumatology

Efficacy and safety of epratuzumab in patients with moderate/severe active systemic lupus erythematosus: results from EMBLEM, a phase IIb, randomised, double-blind, placebo-controlled, multicentre study

(2013) Daniel J Wallace et al.   ANNALS OF THE RHEUMATIC DISEASES

Sifalimumab, a Human Anti-Interferon-α Monoclonal Antibody, in Systemic Lupus Erythematosus: A Phase I Randomized, Controlled, Dose-Escalation Study

(2013) Michelle Petri et al.   ARTHRITIS AND RHEUMATISM

The function of hematopoietic stem cells is altered by both genetic and inflammatory factors in lupus mice

(2013) H. Niu et al.   BLOOD

Systematic Analysis of Donor and Isolation Factor's Impact on Human Islet Yield and Size Distribution

(2013) Y. Wang et al.   CELL TRANSPLANTATION

Allogenic Mesenchymal Stem Cell Transplantation Ameliorates Nephritis in Lupus Mice via Inhibition of B-Cell Activation

(2013) Xiaolei Ma et al.   CELL TRANSPLANTATION

Mesenchymal Stem Cell Transplantation Inhibits Abnormal Activation of Akt/GSK3� Signaling Pathway in T Cells from Systemic Lupus Erythematosus Mice

(2013) Suyun Ji et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Long-term follow-up of autologous stem cell transplantation for severe paediatric systemic lupus erythematosus

(2013) Gaixiu Su et al.   CLINICAL RHEUMATOLOGY

Wnt/β-catenin signaling mediates the senescence of bone marrow-mesenchymal stem cells from systemic lupus erythematosus patients through the p53/p21 pathway

(2013) Zhifeng Gu et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Mesenchymal stem cell treatments in rheumatology—a glass half full?

(2013) Alan Tyndall   Nature Reviews Rheumatology

Real-world costs of autologous and allogeneic stem cell transplantations for haematological diseases: a multicentre study

(2012) H. M. Blommestein et al.   ANNALS OF HEMATOLOGY

Stem cells in autoimmune diseases: Implications for pathogenesis and future trends in therapy

(2012) Paola Cipriani et al.   AUTOIMMUNITY REVIEWS

Emerging and critical issues in the pathogenesis of lupus

(2012) Mariele Gatto et al.   AUTOIMMUNITY REVIEWS

Mesenchymal SCT ameliorates refractory cytopenia in patients with systemic lupus erythematosus

(2012) X Li et al.   BONE MARROW TRANSPLANTATION

Gene Expression Profile Reveals Abnormalities of Multiple Signaling Pathways in Mesenchymal Stem Cell Derived from Patients with Systemic Lupus Erythematosus

(2012) Yu Tang et al.   Clinical & Developmental Immunology

Differential effect of allogeneic versus syngeneic mesenchymal stem cell transplantation in MRL/lpr and (NZB/NZW)F1 mice

(2012) Fei Gu et al.   CLINICAL IMMUNOLOGY

Allogeneic transplantation of umbilical cord-derived mesenchymal stem cells for diffuse alveolar hemorrhage in systemic lupus erythematosus

(2012) Dongyan Shi et al.   CLINICAL RHEUMATOLOGY

Autologous haematopoietic stem cell transplantation for systemic lupus erythematosus: data from the European Group for Blood and Marrow Transplantation registry

(2012) B Alchi et al.   LUPUS

Enhanced Apoptosis and Senescence of Bone-Marrow-Derived Mesenchymal Stem Cells in Patients with Systemic Lupus Erythematosus

(2012) Xia Li et al.   STEM CELLS AND DEVELOPMENT

Activated NF-κB in Bone Marrow Mesenchymal Stem Cells from Systemic Lupus Erythematosus Patients Inhibits Osteogenic Differentiation Through Downregulating Smad Signaling

(2012) Yu Tang et al.   STEM CELLS AND DEVELOPMENT

Reversal of serologic, immunologic, and histologic dysfunction in mice with systemic lupus erythematosus by long-term serial adipose tissue-derived mesenchymal stem cell transplantation

(2011) Eun Wha Choi et al.   ARTHRITIS AND RHEUMATISM

Immune recovery after autologous PBSC transplantation without in vitro graft manipulation for refractory systemic lupus erythematosus

(2011) H Wada et al.   BONE MARROW TRANSPLANTATION

Autologous haemopoietic stem cell transplantation for autoimmune diseases

(2011) Margit Zeher et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Efficacy and safety of belimumab in patients with active systemic lupus erythematosus: a randomised, placebo-controlled, phase 3 trial

(2011) Sandra V Navarra et al.   LANCET

Hematopoietic stem cell transplant for systemic lupus erythematosus: Interferon regulatory factor 7 activation correlates with the IFN signature and recurrent disease

(2011) SE Sweeney   LUPUS

Allogenic mesenchymal stem cells transplantation in refractory systemic lupus erythematosus: a pilot clinical study

(2010) J. Liang et al.   ANNALS OF THE RHEUMATIC DISEASES

Azathioprine versus mycophenolate mofetil for long-term immunosuppression in lupus nephritis: results from the MAINTAIN Nephritis Trial

(2010) F. A. Houssiau et al.   ANNALS OF THE RHEUMATIC DISEASES

Interferon-γ-dependent inhibition of B cell activation by bone marrow-derived mesenchymal stem cells in a murine model of systemic lupus erythematosus

(2010) Francesca Schena et al.   ARTHRITIS AND RHEUMATISM

Umbilical cord mesenchymal stem cell transplantation in severe and refractory systemic lupus erythematosus

(2010) Lingyun Sun et al.   ARTHRITIS AND RHEUMATISM

Therapeutic Effects of Umbilical Cord Blood-Derived Mesenchymal Stem Cell Transplantation in Experimental Lupus Nephritis

(2010) Jei-Wen Chang et al.   CELL TRANSPLANTATION

Transplantation of Human Bone Marrow Mesenchymal Stem Cell Ameliorates the Autoimmune Pathogenesis in MRL/lpr Mice

(2010) Kangxing Zhou et al.   Cellular & Molecular Immunology

Stem cell transplantation: progress in Asia

(2010) L. Sun   LUPUS

Transplantation of umbilical cord mesenchymal stem cells alleviates lupus nephritis in MRL/lpr mice

(2010) Z. Gu et al.   LUPUS

Defective phenotype of mesenchymal stem cells in patients with systemic lupus erythematosus

(2010) Y. Nie et al.   LUPUS

Nonrenal disease activity following mycophenolate mofetil or intravenous cyclophosphamide as induction treatment for lupus nephritis: Findings in a multicenter, prospective, randomized, open-label, parallel-group clinical trial

(2009) Ellen M. Ginzler et al.   ARTHRITIS AND RHEUMATISM

Allogeneic hematopoietic SCT for patients with autoimmune diseases

(2009) T Daikeler et al.   BONE MARROW TRANSPLANTATION

Regulatory T Cell (Treg) Subsets Return in Patients with Refractory Lupus following Stem Cell Transplantation, and TGF- -Producing CD8+ Treg Cells Are Associated with Immunological Remission of Lupus

(2009) L. Zhang et al.   JOURNAL OF IMMUNOLOGY

Autologous mesenchymal stem cell treatment increased T regulatory cells with no effect on disease activity in two systemic lupus erythematosus patients

(2009) F. Carrion et al.   LUPUS

Mesenchymal Stem Cell Transplantation Reverses Multiorgan Dysfunction in Systemic Lupus Erythematosus Mice and Humans

(2009) Lingyun Sun et al.   STEM CELLS

Not a Process of Simple Vicariousness, the Differentiation of Human Adipose-Derived Mesenchymal Stem Cells to Renal Tubular Epithelial Cells Plays an Important Role in Acute Kidney Injury Repairing

(2009) Kanghua Li et al.   STEM CELLS AND DEVELOPMENT

Depletion of autoreactive immunologic memory followed by autologous hematopoietic stem cell transplantation in patients with refractory SLE induces long-term remission through de novo generation of a juvenile and tolerant immune system

(2008) T. Alexander et al.   BLOOD