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Title
Disialoganglioside GD2 as a therapeutic target for human diseases
Authors
Keywords
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Journal
EXPERT OPINION ON THERAPEUTIC TARGETS
Volume 19, Issue 3, Pages 349-362
Publisher
Informa Healthcare
Online
2015-01-21
DOI
10.1517/14728222.2014.986459
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- (2014) Brian H. Kushner et al. CLINICAL CANCER RESEARCH
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- (2014) Ming Cheng et al. INTERNATIONAL JOURNAL OF CANCER
- Key role for myeloid cells: Phase II results of anti-GD2antibody 3F8 plus granulocyte-macrophage colony-stimulating factor for chemoresistant osteomedullary neuroblastoma
- (2014) Nai-Kong V. Cheung et al. INTERNATIONAL JOURNAL OF CANCER
- Phase I Trial of a Novel Anti-GD2 Monoclonal Antibody, Hu14.18K322A, Designed to Decrease Toxicity in Children With Refractory or Recurrent Neuroblastoma
- (2014) Fariba Navid et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2014) Ling Yao et al. Journal of Translational Medicine
- Preclinical Evaluation of Multistep Targeting of Diasialoganglioside GD2 Using an IgG-scFv Bispecific Antibody with High Affinity for GD2 and DOTA Metal Complex
- (2014) S. M. Cheal et al. MOLECULAR CANCER THERAPEUTICS
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- (2014) Mickaël Terme et al. PLoS One
- Endothelin A Receptor Antagonism Enhances Inhibitory Effects of Anti-Ganglioside GD2 Monoclonal Antibody on Invasiveness and Viability of Human Osteosarcoma Cells
- (2014) Bo Liu et al. PLoS One
- GD2-Targeted Immunotherapy and Radioimmunotherapy
- (2014) Konstantin Dobrenkov et al. SEMINARS IN ONCOLOGY
- Structure Based Refinement of a Humanized Monoclonal Antibody That Targets Tumor Antigen Disialoganglioside GD2
- (2014) Mahiuddin Ahmed et al. Frontiers in Immunology
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- (2014) Bryan D Choi et al. OncoImmunology
- Vaccination with anti-idiotype antibody ganglidiomab mediates a GD2-specific anti-neuroblastoma immune response
- (2013) Holger N. Lode et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
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- (2013) Mahiuddin Ahmed et al. FEBS LETTERS
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- (2013) Marie Vincent et al. INTERNATIONAL JOURNAL OF CANCER
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- (2013) Mahiuddin Ahmed et al. PLoS One
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- (2013) Shobhit Saxena et al. PLoS One
- An MRI-Visible Non-Viral Vector Bearing GD2 Single Chain Antibody for Targeted Gene Delivery to Human Bone Marrow Mesenchymal Stem Cells
- (2013) Pengfei Pang et al. PLoS One
- Differential expression profiles of glycosphingolipids in human breast cancer stem cells vs. cancer non-stem cells
- (2013) Y.-J. Liang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2013) Sylvain Julien et al. Cells
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- (2012) S Kailayangiri et al. BRITISH JOURNAL OF CANCER
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- (2012) Mark R. Albertini et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Enhancement of malignant properties of human osteosarcoma cells with disialyl gangliosides GD2/GD3
- (2012) Hidenobu Shibuya et al. CANCER SCIENCE
- Disialyl gangliosides enhance tumor phenotypes with differential modalities
- (2012) Koichi Furukawa et al. GLYCOCONJUGATE JOURNAL
- Unlicensed NK cells target neuroblastoma following anti-GD2 antibody treatment
- (2012) Nidale Tarek et al. JOURNAL OF CLINICAL INVESTIGATION
- Ganglioside GD2 identifies breast cancer stem cells and promotes tumorigenesis
- (2012) Venkata Lokesh Battula et al. JOURNAL OF CLINICAL INVESTIGATION
- Murine Anti-GD2 Monoclonal Antibody 3F8 Combined With Granulocyte-Macrophage Colony-Stimulating Factor and 13-Cis-Retinoic Acid in High-Risk Patients With Stage 4 Neuroblastoma in First Remission
- (2012) Nai-Kong V. Cheung et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2012) H. C. Lee et al. JOURNAL OF IMMUNOLOGY
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- (2012) Anastasia Shibina et al. JOURNAL OF MOLECULAR MEDICINE-JMM
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- (2012) Yuhsuke Ohmi et al. NEUROCHEMICAL RESEARCH
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- (2012) Maxim Yankelevich et al. PEDIATRIC BLOOD & CANCER
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- (2012) Amanda Tivnan et al. PLoS One
- Humanizing murine IgG3 anti-GD2 antibody m3F8 substantially improves antibody-dependent cell-mediated cytotoxicity while retaining targeting in vivo
- (2012) Nai-Kong V. Cheung et al. OncoImmunology
- Expression of GD2 and GD3 Gangliosides in Human Embryonic Neural Stem Cells
- (2011) Makoto Yanagisawa et al. ASN Neuro
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- (2011) C. U. Louis et al. BLOOD
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- (2010) Suzanne Shusterman et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2010) Alice L. Yu et al. NEW ENGLAND JOURNAL OF MEDICINE
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- (2010) Valeria Sordi et al. STEM CELLS
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- (2009) L Li et al. CANCER GENE THERAPY
- Neural Ganglioside GD2 Identifies a Subpopulation of Mesenchymal Stem Cells in Umbilical Cord
- (2009) Jie Xu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Immunogenicity of the Hu14.18-IL2 Immunocytokine Molecule in Adults With Melanoma and Children With Neuroblastoma
- (2009) J. A. Hank et al. CLINICAL CANCER RESEARCH
- The Prioritization of Cancer Antigens: A National Cancer Institute Pilot Project for the Acceleration of Translational Research
- (2009) M. A. Cheever et al. CLINICAL CANCER RESEARCH
- Systematic amino acid substitutions improved efficiency of GD2-peptide mimotope vaccination against neuroblastoma
- (2009) Matthias Bleeke et al. EUROPEAN JOURNAL OF CANCER
- Long-Term Results for Children With High-Risk Neuroblastoma Treated on a Randomized Trial of Myeloablative Therapy Followed by 13-cis-Retinoic Acid: A Children's Oncology Group Study
- (2009) Katherine K. Matthay et al. JOURNAL OF CLINICAL ONCOLOGY
- Reducing Epitope Spread during Affinity Maturation of an Anti-Ganglioside GD2 Antibody
- (2009) J. Hu et al. JOURNAL OF IMMUNOLOGY
- Elevated Levels of Select Gangliosides in T Cells from Renal Cell Carcinoma Patients Is Associated with T Cell Dysfunction
- (2009) S. Biswas et al. JOURNAL OF IMMUNOLOGY
- Compartmental intrathecal radioimmunotherapy: results for treatment for metastatic CNS neuroblastoma
- (2009) Kim Kramer et al. JOURNAL OF NEURO-ONCOLOGY
- High-dose rapid and standard induction chemotherapy for patients aged over 1 year with stage 4 neuroblastoma: a randomised trial
- (2008) Andrew DJ Pearson et al. LANCET ONCOLOGY
- Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
- (2008) Martin A Pule et al. NATURE MEDICINE
- The therapeutic potential of bone marrow-derived mesenchymal stem cells on hepatic cirrhosis
- (2008) Long-Jun Dai et al. Stem Cell Research
- Functional role of glycosphingolipids and gangliosides in control of cell adhesion, motility, and growth, through glycosynaptic microdomains
- (2007) Adriane Regina Todeschini et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Polysialic acid in the plasticity of the developing and adult vertebrate nervous system
- (2007) Urs Rutishauser NATURE REVIEWS NEUROSCIENCE
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